Forscherdatenbank

243 Forscher gefunden.

Name Standort Programm E-Mail / Telefon
Prof. Dr. Carsten Müller-Tidow Heidelberg MDEB, MTT, CI carsten.mueller-tidow@med.uni-heidelberg.de Details
Prof. Dr. Gabriele Multhoff München ROI, CI gabriele.multhoff@tum.de Details
Dr. med. Il-Kang Na Berlin MTT il-kang.na@charite.de Details
Prof. Dr. Gabriele Niedermann Freiburg ROI gabriele.niedermann@uniklinik-freiburg.de Details
Prof. Dr. Charlotte Niemeyer Freiburg MDEB, MTT charlotte.niemeyer@uniklinik-freiburg.de Details
Prof. Dr. med. Konstantin Nikolaou Tübingen ROI konstantin.nikolaou@med.uni-tuebingen.de Details
Prof. Dr. Alfred Nordheim Tübingen EOM, MDEB alfred.nordheim@uni-tuebingen.de Details
Dr. Sebastian Ochsenreither Berlin MDEB, MTT, CI sebastian.ochsenreither@charite.de Details
Prof. Dr. Thomas Oellerich Frankfurt/Mainz MDEB, MTT thomas.oellerich@kgu.de Details
Prof. Dr. Rienk Offringa Heidelberg CI r.offringa@dkfz.de Details
Dr. Christiane Opitz Heidelberg MDEB, CI c.opitz@dkfz.de Details
Priv.-Doz. Dr. Annette Paschen Essen/Düsseldorf CI annette.paschen@uk-essen.de Details
Prof. Dr. Nisar Peter Malek Tübingen MTT nisar.malek@med.uni-tuebingen.de Details
Prof. Dr. Christoph Peters Freiburg EOM christoph.peters@mol-med.uni-freiburg.de Details
Prof. Dr. Stefan Pfister Heidelberg MDEB s.pfister@dkfz.de Details
Prof. Dr. Bernd Pichler Tübingen ROI bernd.pichler@med.uni-tuebingen.de Details
Prof. Dr. Christoph Plass Heidelberg EOM c.plass@dkfz-heidelberg.de Details
Prof. Dr. Karl-Heinz Plate Frankfurt/Mainz MDEB plate@em.uni-frankfurt.de Details
Prof. Dr. Michael Platten Heidelberg CI m.platten@dkfz.de Details
Prof. Dr. Uwe Platzbecker Dresden MTT uwe.platzbecker@uniklinikum-dresden.de Details
Prof. Dr. Tassula Proikas-Cezanne Tübingen EOM tassula.proikas-cezanne@uni-tuebingen.de Details
Prof. Dr. Eugen Proschak Frankfurt/Mainz MTT proschak@pharmchem.uni-frankfurt.de Details
Prof. Dr. Roland Rad München CGP, EOM, MDEB roland.rad@tum.de Details
Dr. med. Olga Radulova-Mauersberger Olga.Radulova-Mauersberger@uniklinikum-dresden.de Details
Prof. Dr. Nikolaus Rajewsky Berlin EOM nikolaus.rajewesky@charite.de Details

DKTK Junior Group Leader for Cancer Systems Biology

Single-cell approaches have not only revealed a wide variety of cell states, characterized by cells exhibiting striking differences in their transcriptional profile, but have also illuminated the mechanisms underlying state transitions in health and disease. Cellular plasticity and adaptive state changes have recently emerged as a basis for therapeutic resistance in cancer, and a better understanding of how cell state transitions are regulated is critical to develop therapeutic approaches that can overcome therapy resistance. 

Our research focuses on understanding the mechanisms driving non-genetic cellular heterogeneity and therapy resistance in malignancy. Using novel single-cell sequencing approaches, we seek to develop new experimental and computational strategies to define altered cell states in both, cancer and immune cells. Our aim is to leverage a data driven strategy combined with single cell genomics and systems biology to address the challenges posed by heterogeneity in cancer, and to develop new strategies to overcome it, with the aim of translating laboratory-based findings into the clinic.