DKTK Publikationen

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Machine Learning Predicts Hepatocellular Carcinoma Risk from Routine Clinical Data: A Large Population-Based Multicentric Study.
Cancer discovery 16(7), 1304 - 1322 () [10.1158/2159-8290.CD-25-1323]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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ADC Target Profiling in NSCLC: Generalizable AI Separates TROP-2 and cMET Phenotypes.
Clinical cancer research 32(13), 2765 - 2786 () [10.1158/1078-0432.CCR-25-4513]  GO BibTeX | EndNote: XML, Text | RIS

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Targeted Radiation, Unintended Evolution.
Clinical cancer research 32(13), 2527 - 2529 () [10.1158/1078-0432.CCR-26-0720]  GO BibTeX | EndNote: XML, Text | RIS

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Molecular changes during AT/RT progression associated with epithelial-mesenchymal transition and extracellular matrix changes.
Acta neuropathologica 152(1), 1 () [10.1007/s00401-026-03050-1]  GO BibTeX | EndNote: XML, Text | RIS

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A deep learning framework for efficient pathology image analysis.
Nature Communications 17(1), 5740 () [10.1038/s41467-026-74918-9]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Feasibility and safety of rapid glofitamab ramp-up.
Leukemia nn, nn () [10.1038/s41375-026-03003-3]  GO BibTeX | EndNote: XML, Text | RIS

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TROP2 targeting reveals therapy-driven cell state dynamics in colorectal cancer.
Nature nn, nn () [10.1038/s41586-026-10705-2]  GO BibTeX | EndNote: XML, Text | RIS

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IDH1-mutant vaccine in newly diagnosed astrocytoma: final analysis of the multicenter, single-arm, open-label, first-in-human phase 1 NOA16 trial.
Nature cancer nn, nn () [10.1038/s43018-026-01199-y]  GO BibTeX | EndNote: XML, Text | RIS

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Cold ischemia time exceeding 12 hours is a risk factor for delayed graft function and increased mortality in kidney transplant recipients within the eurotransplant senior program.
Transplant international 39, 15840 () [DOI:10.3389/ti.2026.15840]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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The HLH-Risk-Calculator is a machine learning-based tool to predict course & mortality of secondary hemophagocytic lymphohistiocytosis.
Intensive care medicine nn, nn () [10.1007/s00134-026-08515-1]  GO BibTeX | EndNote: XML, Text | RIS

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Genome-wide copy number analysis identifies AKT as a novel therapeutic target in pleural mesothelioma.
Lung cancer 218, 109512 () [10.1016/j.lungcan.2026.109512]  GO BibTeX | EndNote: XML, Text | RIS

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Lineage-restricted dependency on an oncofetal SNHG29-IGF2BP1 RNA axis in acute megakaryoblastic leukemia.
Leukemia nn, nn () [10.1038/s41375-026-03040-y]  GO BibTeX | EndNote: XML, Text | RIS

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AURORA A interacts with DICER and SETD2 to promote S-phase progression.
EMBO reports nn, nn () [10.1038/s44319-026-00850-0]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Clinical decision support in hematological malignancies using a case-grounded AI agent.
Nature medicine nn, nn () [10.1038/s41591-026-04494-4]  GO BibTeX | EndNote: XML, Text | RIS

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„First-in-human“-Studie mit dem Antikörper CC-1 beim CRPC
Aktuelle Urologie 57(03), 250 - 252 () [10.1055/a-2841-6607]  GO BibTeX | EndNote: XML, Text | RIS

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Therapy and biomarker dependent progression-free survival in infant sonic hedgehog medulloblastoma: a multi-national retrospective cohort study.
EClinicalMedicine 96, 103913 () [10.1016/j.eclinm.2026.103913]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Incidence and impact of intracranial complications in patients undergoing extracorporeal membrane oxygenation treatment.
Brain and spine 6, 106123 () [10.1016/j.bas.2026.106123]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Needle-track metastasis in diffuse intrinsic pontine glioma: Need for a standardized surgical strategy?
Neuro-oncology advances 8(1), vdag155 () [10.1093/noajnl/vdag155]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Recent survival trends in the most fatal cancers in the Nordic countries: gains in some but not in all.
Acta oncologica 65, 578 - 581 () [10.2340/1651-226X.2026.45868]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Efficacy and Safety Differences Between Abiraterone and Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Meta-analysis of Real-World Studies.
Targeted oncology nn, nn () [10.1007/s11523-026-01230-3]  GO BibTeX | EndNote: XML, Text | RIS

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Menin-MLL inhibitors enhance JUND activity in MLLr leukemic cells contributing to tumorigenesis and therapy resistance.
Blood nn, nn () [10.1182/blood.2025032363]  GO BibTeX | EndNote: XML, Text | RIS

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Continuous multi-omics pathway enrichment analysis resolves hidden functional heterogeneity.
Briefings in bioinformatics 27(3), bbag328 () [10.1093/bib/bbag328]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Beyond the first dose: Systematic review on external beam radiotherapy for locoregional breast cancer recurrence.
The breast 88, 104847 () [10.1016/j.breast.2026.104847]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Dose escalation with intraoperative radiotherapy in newly diagnosed glioblastoma (INTRAGO-II): an open-label, multicentre, randomised, controlled, phase 3 trial.
The lancet / Oncology 27(7), 864 - 878 () [10.1016/S1470-2045(26)00235-4]  GO BibTeX | EndNote: XML, Text | RIS

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European guideline for imaging of primary paediatric and adult osteosarcoma and Ewing sarcoma: systematic review and joint statement by the FOSTER consortium, Euro Ewing Consortium, European Society of Paediatric Radiology, and the European Association of Nuclear Medicine.
The lancet / Oncology 27(7), e339 - e349 () [10.1016/S1470-2045(26)00141-5]  GO BibTeX | EndNote: XML, Text | RIS

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Imaging the hallmarks of cancer.
Nature reviews / Cancer nn, nn () [10.1038/s41568-026-00950-y]  GO BibTeX | EndNote: XML, Text | RIS

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The evolving role of cytokines for CAR-T cell manufacturing and beyond.
Nature biomedical engineering nn, nn () [10.1038/s41551-026-01703-w]  GO BibTeX | EndNote: XML, Text | RIS

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A retargeted recombinase for precise insertion of large DNA.
Nature biotechnology nn, nn () [10.1038/s41587-026-03198-x]  GO BibTeX | EndNote: XML, Text | RIS

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CircZBTB46, a promising therapeutic target in crizotinib resistant ALK-positive T lymphomas.
Leukemia nn, nn () [10.1038/s41375-026-03018-w]  GO BibTeX | EndNote: XML, Text | RIS

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Early neutrophil infiltration promotes TRIMELVax-induced antitumor immunity by linking local inflammation to tumor control.
OncoImmunology 15(1), 2680766 () [10.1080/2162402X.2026.2680766]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Long-term outcomes and late effects of surgery and radiotherapy in adult intracranial ependymoma patients.
Journal of neuro-oncology 178(3), 78 () [10.1007/s11060-026-05680-7]  GO BibTeX | EndNote: XML, Text | RIS

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Enhanced IGFL1 translation in response to IL-1β is controlled by distinct 3'UTR elements.
PLOS ONE 21(6), e0342288 - () [10.1371/journal.pone.0342288]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Donor Selection and Human Leukocyte Antigen Loss Leukemia Relapse After Hematopoietic Cell Transplantation.
Journal of clinical oncology nn, nn () [10.1200/JCO-26-00113]  GO BibTeX | EndNote: XML, Text | RIS

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SSTR-Targeted Radiotheranostics in Breast Cancer: A Comparison of [68Ga]Ga-DOTATOC and [68Ga]Ga-SSO120 with [18F]FDG PET.
Journal of nuclear medicine nn, nn () [10.2967/jnumed.126.272521]  GO BibTeX | EndNote: XML, Text | RIS

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Teclistamab-based induction treatment in transplant-eligible, newly diagnosed multiple myeloma: a phase 2 trial.
Nature medicine nn, nn () [10.1038/s41591-026-04471-x]  GO BibTeX | EndNote: XML, Text | RIS

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Reduced DPP9 levels sensitize experimental breast tumors to combinatory treatment with irradiation and Olaparib.
Frontiers in oncology 16, 1845048 () [10.3389/fonc.2026.1845048]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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„First-in-human“-Studie mit dem Antikörper CC-3 beim Peniskarzinom
Aktuelle Urologie 57(03), 248 - 249 () [10.1055/a-2703-9949]  GO BibTeX | EndNote: XML, Text | RIS

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Integrity in Radiation Oncology Research: A Systematic Review of Retracted Studies, Retraction Notices, and Their Impact on the Field
Advances in radiation oncology 11(8), 102071 () [10.1016/j.adro.2026.102071]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Matched sampling reveals uncoupled phenotypic plasticity during metastasis formation in uveal melanoma
iScience 29(7), 116397 () [10.1016/j.isci.2026.116397]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Impact on Cost and Expert Time of Data-Efficient Deep Learning for Medical Image Segmentation.
Radiology: artificial intelligence nn, nn () [10.1148/ryai.250200]  GO BibTeX | EndNote: XML, Text | RIS

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Flawed translation triggers oncogenic B-T cell communication.
Journal of experimental medicine 223(8), e20260912 () [10.1084/jem.20260912]  GO BibTeX | EndNote: XML, Text | RIS

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Guidance for the Diagnosis and Treatment of Rare Embryonal and Sarcomatous Brain Tumors—a Report from the Central Nervous System-International Registry for Rare Embryonal and Sarcomatous Tumors German Society of Pediatric Oncology and Hematology Study Group. [Interdisziplinäre Empfehlungen zur Diagnostik und Therapie seltener embryonaler und sarkomatöser ZNS-Tumoren im Kindes- und Jugendalter].
Klinische Pädiatrie nn, nn () [10.1055/a-2889-3506]  GO BibTeX | EndNote: XML, Text | RIS

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Integrated transcriptomic and TCR profiling reveals local immune dysregulation of T cells in Gl aGvHD.
Bone marrow transplantation nn, nn () [10.1038/s41409-026-02942-w]  GO BibTeX | EndNote: XML, Text | RIS

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Varun Venkataramani: the rise of cancer neuroscience.
Nature reviews / Neurology nn, nn () [10.1038/s41582-026-01240-9]  GO BibTeX | EndNote: XML, Text | RIS

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Academic point-of-care anti-CD19 CAR T-cell therapy induces durable remission and transient paroxysmal nocturnal hemoglobinuria-type cell expansion in a patient with multi-refractory immune thrombocytopenia.
Haematologica nn, nn () [10.3324/haematol.2026.300887]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Comparative Analysis of the Prognostic Value of Simpson Grade Versus MRI-Based Extent of Resection Paradigms Across Meningioma Histomolecular Subgroups.
Neurosurgery nn, nn () [10.1227/neu.0000000000004140]  GO BibTeX | EndNote: XML, Text | RIS

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Hyperpolarization of [1-13C]Ketoisocaproate-d2 by Reversible Exchange with Parahydrogen Enables Profiling of Branched-Chain-Amino-Acid Metabolism in Cellulo and in Vivo.
Advanced science nn, nn () [10.1002/advs.76213]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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The role of capacitive hyperthermia as an adjunct treatment in oncology: a systematic review of randomized phase III trials.
International journal of hyperthermia and thermal therapies 43(1), 2678876 () [10.1080/02656736.2026.2678876]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Outcome after primary directed radiotherapy in predominantly PSMA-PET/CT-staged patients with metastatic prostate cancer.
EJNMMI Research 16(1), 100 () [10.1186/s13550-026-01473-1]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Host metabolism can produce many indoles and phenols independently of the microbiome.
Nature metabolism nn, nn () [10.1038/s42255-026-01550-8]  GO BibTeX | EndNote: XML, Text | RIS