Selected Publications

Mayerhofer C, Li D, Kristiansen T, Mayerhofer E, Sharda A, Schiroli G, Gustafsson K, He L, Mazzola M, Keyes S, Kiem A, Crompton E, Xu Y, Korm S, Dou Z, Vidoudez C, Miller PG, van Gastel N, Graubert TA, Scadden DT. OGFOD1 enables AML
chemo- and nutrient stress resistance by regulating protein synthesis. Cell Metab. 2025 Oct 7;37(10):2014-2029.e9. doi: 10.1016/j.cmet.2025.08.008. Epub 2025 Sep 16. PMID: 40961937; PMCID: PMC12490346.

Mayerhofer C, Crompton E, Mayerhofer E, Kristiansen T, Fukushima T, Keyes S, Sharda A, Li D, Da Silva C, Shrestha D, Kiem A, Feuchtinger T, Scadden DT, Miller PG. Studying clonal heterogeneity of acute myeloid leukemia under nutrient and chemotherapy stress. Blood Adv. 2026 Feb 24;10(4):1272-1277. doi:10.1182/bloodadvances.2025016618. PMID: 41351481; PMCID: PMC12925107.

He L, Zhao T, Leong WZ, Sharda A, Mayerhofer C, Mei S, Bonilla GM, Menendez-Gonzalez JB, Gustafsson K, Fukushima T, Kristiansen TA, Lee JW, Xu Y, Chen L, Xia J, Orozco LA, Budnik B, Sadreyev R, Dou Z, Sykes DB, Scadden DT. PSTK inhibition activates cGAS-STING, precipitating ferroptotic cell death in leukemic stem cells. Blood. 2025 Apr 24;145(17):1903-1914. doi:10.1182/blood.2024026040. PMID: 39912669; PMCID: PMC13169314.

Mayerhofer C, Freedman RA, Parsons HA, Partridge AH, Miller PG. Clonal Hematopoiesis in Women With Breast Cancer. J Clin Oncol. 2025 Mar;43(7):861-867.doi: 10.1200/JCO-24-01848. Epub 2025 Jan 17. PMID: 39823557; PMCID: PMC11867839.

Miller PG, Sperling AS, Mayerhofer C, McConkey ME, Ellegast JM, Da Silva C, Cohen DN, Wang C, Sharda A, Yan N, Saha S, Schluter C, Schechter I, Słabicki M, Sandoval B, Kahn J, Boettcher S, Gibson CJ, Scadden DT, Stegmaier K, Bhatt S, Lindsley RC, Ebert BL. PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy. Blood. 2023 Dec 14;142(24):2079-2091. doi: 10.1182/blood.2023020331. PMID: 37595362; PMCID: PMC10733824.