Selected Publications
Cell-specific analysis of microglia following partial brain proton irradiation in mice.
Nexhipi S, Suckert T, Soltwedel J, Beyreuther E, Noßol M, Pecht L, Boucsein M, Schneider M, Horst F, Löck S, Krause M, Lühr A, Dietrich A. Clin Transl Radiat Oncol. 2025 Jun 27;54:101003. doi: 10.1016/j.ctro.2025.101003. eCollection 2025 Sep. PMID: 40687733 Free PMC article.
Type I conventional dendritic cells and CD8+ T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients.
Kirchner J, Plesca I, Rothe R, Resag A, Löck S, Benešová I, Rupp L, Linge A, Wehner R, Krause M, Schmitz M. Front Immunol. 2024 Jun 13;15:1414298. doi: 10.3389/fimmu.2024.1414298. eCollection 2024. PMID: 38938577 Free PMC article.
The value of subcutaneous xenografts for individualised radiotherapy in HNSCC: Robust gene signature correlates with radiotherapy outcome in patients and xenografts.
Linge A, Patil S, Grosser M, Lohaus F, Gurtner K, Kemper M, Gudziol V, Haim D, Nowak A, Tinhofer I, Zips D, Guberina M, Stuschke M, Balermpas P, Rödel C, Schäfer H, Grosu AL, Abdollahi A, Debus J, Ganswindt U, Belka C, Pigorsch S, Combs SE, Boeke S, Gani C, Jöhrens K, Baretton GB, Löck S, Baumann M, Krause M; DKTK-ROG. Radiother Oncol. 2024 Feb;191:110055. doi: 10.1016/j.radonc.2023.110055. Epub 2023 Dec 16. PMID: 38109944 Free article.
Prognostic biomarkers for the response to the radiosensitizer nimorazole combined with RCTx: a pre-clinical trial in HNSCC xenografts.
Koi L, Bitto V, Weise C, Möbius L, Linge A, Löck S, Yaromina A, Besso MJ, Valentini C, Pfeifer M, Overgaard J, Zips D, Kurth I, Krause M, Baumann M. J Transl Med. 2023 Aug 26;21(1):576. doi: 10.1186/s12967-023-04439-2. PMID: 37633930 Free PMC article.
Slice2Volume: Fusion of multimodal medical imaging and light microscopy data of irradiation-injured brain tissue in 3D.
Soltwedel J, Suckert T, Beyreuther E, Schneider M, Boucsein M, Bodenstein E, Nexhipi S, Stolz-Kieslich L, Krause M, von Neubeck C, Haase R, Lühr A, Dietrich A. Radiother Oncol. 2023 May;182:109591. doi: 10.1016/j.radonc.2023.109591. Epub 2023 Feb 28. PMID: 36858201 Free article.
Development and validation of a 6-gene signature for the prognosis of loco-regional control in patients with HPV-negative locally advanced HNSCC treated by postoperative radio(chemo)therapy.
Patil S, Linge A, Grosser M, Lohaus F, Gudziol V, Kemper M, Nowak A, Haim D, Tinhofer I, Budach V, Guberina M, Stuschke M, Balermpas P, Rödel C, Schäfer H, Grosu AL, Abdollahi A, Debus J, Ganswindt U, Belka C, Pigorsch S, Combs SE, Boeke S, Zips D, Baretton GB, Baumann M, Krause M, Löck S; DKTK-ROG. Radiother Oncol. 2022 Jun;171:91-100. doi: 10.1016/j.radonc.2022.04.006. Epub 2022 Apr 13. PMID: 35429503
Biomarker signatures for primary radiochemotherapy of locally advanced HNSCC - Hypothesis generation on a multicentre cohort of the DKTK-ROG.
Löck S, Linge A, Lohaus F, Ebert N, Gudziol V, Nowak A, Tinhofer I, Kalinauskaite G, Guberina M, Stuschke M, Balermpas P, von der Grün J, Grosu AL, Debus J, Ganswindt U, Belka C, Peeken JC, Combs SE, De-Colle C, Zips D, Baretton GB, Krause M, Baumann M; DKTK-ROG. Radiother Oncol. 2022 Apr;169:8-14. doi: 10.1016/j.radonc.2022.02.009. Epub 2022 Feb 16. PMID: 35182686
Analyses of molecular subtypes and their association to mechanisms of radioresistance in patients with HPV-negative HNSCC treated by postoperative radiochemotherapy.
Patil S, Tawk B, Grosser M, Lohaus F, Gudziol V, Kemper M, Nowak A, Haim D, Tinhofer I, Budach V, Guberina M, Stuschke M, Balermpas P, Rödel C, Schäfer H, Grosu AL, Abdollahi A, Debus J, Ganswindt U, Belka C, Pigorsch S, Combs SE, Boeke S, Zips D, Baretton GB, Baumann M, Krause M, Löck S, Linge A; DKTK-ROG. Radiother Oncol. 2022 Feb;167:300-307. doi: 10.1016/j.radonc.2021.12.049. Epub 2022 Jan 6. PMID: 34999136
Radiotherapy enhances uptake and efficacy of 90Y-cetuximab: A preclinical trial.
Dietrich A, Andreeff M, Koi L, Bergmann R, Schubert M, Schreiner L, Löck S, Sihver W, Freudenberg R, Hering S, Pietzsch HJ, Steinbach J, Kotzerke J, Baumann M, Krause M. Radiother Oncol. 2021 Feb;155:285-292. doi: 10.1016/j.radonc.2020.11.013. Epub 2020 Nov 21. PMID: 33227356 Free article.
Late Side Effects in Normal Mouse Brain Tissue After Proton Irradiation.
Suckert T, Beyreuther E, Müller J, Azadegan B, Meinhardt M, Raschke F, Bodenstein E, von Neubeck C, Lühr A, Krause M, Dietrich A. Front Oncol. 2021 Jan 11;10:598360. doi: 10.3389/fonc.2020.598360. eCollection 2020. PMID: 33520710 Free PMC article.
Final Results of the Prospective Biomarker Trial PETra: [11C]-MET-Accumulation in Postoperative PET/MRI Predicts Outcome after Radiochemotherapy in Glioblastoma.
Seidlitz A, Beuthien-Baumann B, Löck S, Jentsch C, Platzek I, Zöphel K, Linge A, Kotzerke J, Petr J, van den Hoff J, Steinbach J, Krex D, Schmitz-Schackert G, Falk M, Baumann M, Krause M. Clin Cancer Res. 2021 Mar 1;27(5):1351-1360. doi: 10.1158/1078-0432.CCR-20-1775. Epub 2020 Dec 29. PMID: 33376095