2023
Li L, Mohanty V, Dou J, Huang Y, Banerjee PP, Miao Q, Lohr JG, Vijaykumar T, Frede J, Knoechel B, Muniz-Feliciano L, Laskowski TJ, Liang S, Moyes JS, Nandivada V, Basar R, Kaplan M, Daher M, Liu E, Li Y, Acharya S, Lin P, Shanley M, Rafei H, Marin D, Mielke S, Champlin RE, Shpall EJ, Chen K, Rezvani K. Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering. Sci Adv. 2023 Jul 28;9(30):eadd6997.
2022
Im NG, Guillaumet-Adkins A, Wal M, Rogers AJ, Frede J, Havig CC, Yang J, Anand P, Stegmann SK, Waldschmidt JM, Sotudeh N, Niu L, Voisine J, Schweiger MR, Grassberger C, Lohr JG, Knoechel B. Regulatory programs of B-cell activation and germinal center reaction allow B-ALL escape from CD19 CAR T-cell therapy. Cancer Immunol Res. 2022 Sep 1;10(9):1055-1068.
Waldschmidt JM, Yee AJ, Vijaykumar T, Rengifo RP, Frede J, Anand P, Guo G, Potdar S, Seifer C, Nair M, Kokkalis A, Kloeber JA, Shapiro S, Mann M, Friedman R, Lipe B, Campagnaro E, O'Donnell E, Zhang CZ, Laubach J, Munshi N, Richardson P, Anderson K, Raje N, Knoechel B, Lohr J. Cell-free DNA for the detection of emerging treatment failure in relapsed/ refractory multiple myeloma. Leukemia. 2022 Apr;36(4):1078-1087.
2021
Waldschmidt JM, Kloeber JA, Anand P, Frede J, Kokkalis A, Dimitrova V, Potdar S, Nair MS, Vijaykumar T, Im NG, Guillaumet-Adkins A, Guo G, Yee AJ, Laubach JP, Richardson PG, Anderson KC, Raje NS, Knoechel B, Lohr JG. Transcriptional adaption and enhancer rewiring promote metabolic resistance in BRAF-mutated multiple myeloma. Clin Cancer Res. 2021 Dec 1;27(23):6432-6444.
Frede J, Anand P, Sotudeh N, Pinto RA, Nair MS, Stuart H, Yee AJ, Vijaykumar T, Waldschmidt JM, Potdar S, Kloeber JA, Kokkalis A, Dimitrova V, Mann M, Laubach JP, Richardson PG, Anderson KC, Raje NS, Knoechel B, Lohr JG. Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma. Nat Cell Biol. 2021 Nov;23(11):1199-1211.
Anand P, Guillaumet-Adkins A, Dimitrova V, Yun H, Drier Y, Sotudeh N, Rogers AJ, Ouseph MM, Nair M, Potdar S, Isenhart R, Kloeber JA, Vijaykumar T, Niu L, Vincent TL, Guo G, Frede J, Harris M, Place A, Silverman LB, Teachey DT, Lane AA, DeAngelo DJ, Aster JC, Bernstein B, Lohr JG, Knoechel B. Single cell RNA-seq reveals developmental plasticity with coexisting oncogenic and immune evasion programs in ETP-ALL. Blood. 2021 May 6;137(18):2463-2480.