DKTK Publications (PubMed)

Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond.

Authors: Platten M, Nollen EAA, Röhrig UF, Fallarino F, Opitz CA

Published: Feb 2019 / Journal: Nat Rev Drug Discov
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Salinomycin: Anti-tumor activity in a pre-clinical colorectal cancer model.

Authors: Klose J, Trefz S, Wagner T, Steffen L, Preißendörfer Charrier A, Radhakrishnan P, Volz C, Schmidt T, Ulrich A, Dieter SM, Ball C, Glimm H, Schneider M

Published: Feb 2019 / Journal: PLoS One
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Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC).

Authors: Buczak K, Ori A, Kirkpatrick JM, Holzer K, Dauch D, Roessler S, Endris V, Lasitschka F, Parca L, Schmidt A, Zender L, Schirmacher P, Krijgsveld J, Singer S, Beck M

Published: Feb 2019 / Journal: Mol Cell Proteomics
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Gαs-coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells.

Authors: Dimitrov S, Lange T, Gouttefangeas C, Jensen ATR, Szczepanski M, Lehnnolz J, Soekadar S, Rammensee HG, Born J, Besedovsky L

Published: Feb 2019 / Journal: J Exp Med
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Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA.

Authors: Hou Y, Pinheiro J, Sahm F, Reuss DE, Schrimpf D, Stichel D, Casalini B, Koelsche C, Sievers P, Wefers AK, Reinhardt A, Ebrahimi A, Fernández-Klett F, Pusch S, Meier J, Schweizer L, Paulus W, Prinz M, Hartmann C, Plate KH, Reifenberger G, Pietsch T, Varlet P, Pagès M, Schüller U, Scheie D, de Stricker K, Frank S, Hench J, Pollo B, Brandner S, Unterberg A, Pfister SM, Jones DTW, Korshunov A, Wick W, Capper D, Blümcke I, von Deimling A, Bertero L

Published: Feb 2019 / Journal: Acta Neuropathol
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Therapeutic opportunities based on caspase modulation.

Authors: Fulda S

Published: Feb 2019 / Journal: Semin Cell Dev Biol
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Systematic Generation of Patient-Derived Tumor Models in Pancreatic Cancer.

Authors: Ehrenberg KR, Gao J, Oppel F, Frank S, Kang N, Dieter SM, Herbst F, Möhrmann L, Dubash TD, Schulz ER, Strakerjahn H, Giessler KM, Weber S, Oberlack A, Rief EM, Strobel O, Bergmann F, Lasitschka F, Weitz J, Glimm H, Ball CR

Published: Feb 2019 / Journal: Cells
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The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma.

Authors: Foltyn M, Luger AL, Lorenz NI, Sauer B, Mittelbronn M, Harter PN, Steinbach JP, Ronellenfitsch MW

Published: Feb 2019 / Journal: Br J Cancer
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Radiochemotherapy combined with NK cell transfer followed by second-line PD-1 inhibition in a patient with NSCLC stage IIIb inducing long-term tumor control: a case study.

Authors: Kokowski K, Stangl S, Seier S, Hildebrandt M, Vaupel P, Multhoff G

Published: Feb 2019 / Journal: Strahlenther Onkol
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Machine learning-based predictors for immune checkpoint inhibitor therapy of non-small cell lung cancer.

Authors: Wiesweg M, Mairinger F, Reis H, Goetz M, Walter RFH, Hager T, Metzenmacher M, Eberhardt WEE, McCutcheon A, Köster J, Stuschke M, Aigner C, Darwiche K, Schmid KW, Rahmann S, Schuler M

Published: Feb 2019 / Journal: Ann Oncol
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The administration route of tumor-antigen-specific T-helper cells differentially modulates the tumor microenvironment and senescence.

Authors: Griessinger CM, Schmid AM, Sonanini D, Schörg BF, Jarboui MA, Bukala D, Mucha N, Fehrenbacher B, Steinhilber J, Martella M, Kohlhofer U, Schaller M, Zender L, Rammensee HG, Quintanilla-Martinez L, Röcken M, Kneilling M, Pichler BJ

Published: Feb 2019 / Journal: Carcinogenesis
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Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.

Authors: Shukla SA, Bachireddy P, Schilling B, Galonska C, Zhan Q, Bango C, Langer R, Lee PC, Gusenleitner D, Keskin DB, Babadi M, Mohammad A, Gnirke A, Clement K, Cartun ZJ, Van Allen EM, Miao D, Huang Y, Snyder A, Merghoub T, Wolchok JD, Garraway LA, Meissner A, Weber JS, Hacohen N, Neuberg D, Potts PR, Murphy GF, Lian CG, Schadendorf D, Hodi FS, Wu CJ

Published: Feb 2019 / Journal: Cell
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Impact of radiation, systemic therapy and treatment sequencing on survival of patients with melanoma brain metastases.

Authors: Rauschenberg R, Bruns J, Brütting J, Daubner D, Lohaus F, Zimmer L, Forschner A, Zips D, Hassel JC, Berking C, Kaehler KC, Utikal J, Gutzmer R, Terheyden P, Meiss F, Rafei-Shamsabadi D, Kiecker F, Debus D, Dabrowski E, Arnold A, Garzarolli M, Kuske M, Beissert S, Löck S, Linn J, Troost EGC, Meier F

Published: Feb 2019 / Journal: Eur J Cancer
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Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma.

Authors: Dallmayer M, Li J, Ohmura S, Alba Rubio R, Baldauf MC, Hölting TLB, Musa J, Knott MML, Stein S, Cidre-Aranaz F, Wehweck FS, Romero-Pérez L, Gerke JS, Orth MF, Marchetto A, Kirchner T, Bach H, Sannino G, Grünewald TGP

Published: Feb 2019 / Journal: Cell Death Dis
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Cell cycle arrest in mitosis promotes interferon-induced necroptosis.

Authors: Frank T, Tuppi M, Hugle M, Dötsch V, van Wijk SJL, Fulda S

Published: Feb 2019 / Journal: Cell Death Differ
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