DKTK Publications

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A plain language summary of the 7-year update from part 1 of the COLUMBUS study: encorafenib and binimetinib for people with BRAF V600-mutant melanoma.
Future oncology nn, nn () [10.1080/14796694.2024.2442851]  GO BibTeX | EndNote: XML, Text | RIS

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Single-cell transcriptomics and epigenomics point to CD58-CD2 interaction in controlling primary melanoma growth and immunity.
Cancer communications nn, nn () [10.1002/cac2.12651]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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RECQL4 affects MHC class II-mediated signalling and favours an immune-evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma.
Clinical and translational medicine 15(1), e70094 () [10.1002/ctm2.70094]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Maintenance treatment with trofosfamide in patients with advanced soft tissue sarcoma - a retrospective single-centre analysis.
Acta oncologica 64, 56 - 62 () [10.2340/1651-226X.2025.42356]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Herpesviruses mimic zygotic genome activation to promote viral replication.
Nature Communications 16(1), 710 () [10.1038/s41467-025-55928-5]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Prognostic impact of expression of CD2, CD25, and/or CD30 in/on mast cells in systemic mastocytosis: a registry study of the European Competence Network on Mastocytosis.
Leukemia nn, nn () [10.1038/s41375-024-02504-3]  GO BibTeX | EndNote: XML, Text | RIS

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Pediatric high-grade gliomas with concomitant RB1 and SETD2 alterations and Li-Fraumeni syndrome.
Acta Neuropathologica Communications 13(1), 8 () [10.1186/s40478-024-01885-x]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Patientensicherheit in der palliativen Chirurgie.
Die Chirurgie nn, nn () [10.1007/s00104-024-02202-x]  GO BibTeX | EndNote: XML, Text | RIS

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Simultaneous integrated boost to lateral pelvic lymph nodes during chemoradiotherapy in high-risk rectal cancer.
Strahlentherapie und Onkologie nn, nn () [10.1007/s00066-024-02354-z]  GO BibTeX | EndNote: XML, Text | RIS

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Prognostic significance of immune reconstitution following CD19 CAR T-cell therapy for relapsed/refractory B-cell lymphoma.
HemaSphere 9(1), e70062 () [10.1002/hem3.70062]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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TIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells.
Cancer discovery 15(1), 179 - 201 () [10.1158/2159-8290.CD-24-0134]  GO BibTeX | EndNote: XML, Text | RIS

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Neural invasion severity is a strong predictor of local recurrence in pancreatic ductal adenocarcinoma.
Surgery 180, 109018 () [10.1016/j.surg.2024.109018]  GO BibTeX | EndNote: XML, Text | RIS

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Nutrition Care in Cancer: An Overlooked Part of Patient-Centered Care.
Seminars in oncology nursing nn, nn () [10.1016/j.soncn.2024.151799]  GO BibTeX | EndNote: XML, Text | RIS

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Accounting for differential exclusions in the NordICC trial discloses stronger-than-reported effects of screening colonoscopy.
Journal of clinical epidemiology nn, nn () [10.1016/j.jclinepi.2025.111669]  GO BibTeX | EndNote: XML, Text | RIS

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Unveiling Targets and Resistance in FGFR-Altered Cancers.
Annals of oncology nn, nn () [10.1016/j.annonc.2025.01.002]  GO BibTeX | EndNote: XML, Text | RIS

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Deep imaging of LepR+ stromal cells in optically cleared murine bone hemisections.
Bone research 13(1), 6 () [10.1038/s41413-024-00387-9]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Cancer Neuroscience of Brain Tumors: From Multicellular Networks to Neuroscience-Instructed Cancer Therapies.
Cancer discovery 15(1), 39 - 51 () [10.1158/2159-8290.CD-24-0194]  GO BibTeX | EndNote: XML, Text | RIS

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A first-in-human phase 1/2 dose-escalation study of MAK683 (EED inhibitor) in patients with advanced malignancies.
European journal of cancer 216, 115122 () [10.1016/j.ejca.2024.115122]  GO BibTeX | EndNote: XML, Text | RIS

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Translational and clinical comparison of whole genome and transcriptome to panel sequencing in precision oncology.
npj precision oncology 9(1), 9 () [10.1038/s41698-024-00788-3]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Staging of prostate Cancer with ultra-fast PSMA-PET scans enhanced by AI.
European journal of nuclear medicine and molecular imaging nn, nn () [10.1007/s00259-024-07060-7]  GO BibTeX | EndNote: XML, Text | RIS

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The Role of Glucose-6-Phosphate Dehydrogenase in Skin Cancer Metabolism: A Paradigm Shift in Treatment Approaches.
Cancers 17(1), 48 () [10.3390/cancers17010048]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Primary Mediastinal Ewing's Sarcoma: Post Hoc Analysis from Two International Multicenter Prospective Randomized Trials.
Cancers 17(1), 118 () [10.3390/cancers17010118]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Correction: Overall survival of patients with KIT-mutant metastatic GIST in the era of multiple kinase inhibitor availability.
Journal of cancer research and clinical oncology 151(1), 33 () [10.1007/s00432-024-06056-y]  GO BibTeX | EndNote: XML, Text | RIS

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Definitive Radiochemotherapie des Ösophaguskarzinoms: etablierte Therapie und neue StandardsDefinitive radiochemotherapy of esophageal cancer: established treatment and new standards
Die Onkologie nn, nn () [10.1007/s00761-024-01645-5]  GO BibTeX | EndNote: XML, Text | RIS

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Inhibiting H3K27 Demethylases Downregulates CREB-CREBBP, Overcoming Resistance in Relapsed Acute Lymphoblastic Leukemia.
Cancer medicine 14(1), 1 - 7 () [10.1002/cam4.70596]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Flow Cytometric Assessment of FcγRIIIa-V158F Polymorphisms and NK Cell Mediated ADCC Revealed Reduced NK Cell Functionality in Colorectal Cancer Patients.
Cells 14(1), 32 () [10.3390/cells14010032]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Patient- and clinician-based evaluation of large language models for patient education in prostate cancer radiotherapy.
Strahlentherapie und Onkologie nn, nn () [10.1007/s00066-024-02342-3]  GO BibTeX | EndNote: XML, Text | RIS

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Influence of radiotherapy on cardiac implantable devices and leads-a single-institution analysis and critical evaluation of current guidelines.
Strahlentherapie und Onkologie nn, nn () [10.1007/s00066-024-02345-0]  GO BibTeX | EndNote: XML, Text | RIS

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Implant-based reconstruction and adjuvant radiotherapy in breast cancer patients-current status and DEGRO recommendations.
Strahlentherapie und Onkologie nn, nn () [10.1007/s00066-024-02334-3]  GO BibTeX | EndNote: XML, Text | RIS

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Everolimus with or without mycophenolate mofetil for GVHD prophylaxis after allogeneic HSCT in children with acute kidney injury - a single-center retrospective analysis.
Transplantation and cellular therapy nn, nn () [10.1016/j.jtct.2025.01.002]  GO BibTeX | EndNote: XML, Text | RIS

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High Ano1 expression as key driver of resistance to radiation and cisplatin in HPV-negative head and neck squamous cell carcinoma.
Scientific reports 15(1), 1555 () [10.1038/s41598-025-85214-9]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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To what extent is the association between obesity and colorectal cancer risk mediated by systemic inflammation?
Cancer communications nn, nn () [DOI:10.1002/cac2.12659]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Recipient sex and donor leukemic cell characteristics determine leukemogenesis in patient-derived models.
Haematologica nn, nn () [10.3324/haematol.2023.284647]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Smad2 Cooperating with TGIF2 Contributes to EMT and Cancer Stem Cells Properties in Pancreatic Cancer via Co-Targeting SOX2.
International journal of biological sciences 21(2), 524 - 543 () [10.7150/ijbs.102381]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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The potential of GPT-4 advanced data analysis for radiomics-based machine learning models.
Neuro-oncology advances 7(1), vdae230 () [10.1093/noajnl/vdae230]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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PTMNavigator: interactive visualization of differentially regulated post-translational modifications in cellular signaling pathways.
Nature Communications 16(1), 510 () [10.1038/s41467-024-55533-y]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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SarkoLife: quality of life in patients undergoing multimodal soft tissue sarcoma treatment.
World journal of surgical oncology 23(1), 10 () [10.1186/s12957-024-03632-x]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Development and validation of a molecular classifier of meningiomas.
Neuro-Oncology nn, nn () [10.1093/neuonc/noae242]  GO BibTeX | EndNote: XML, Text | RIS

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Role of the tumor board when prescribing mutant isocitrate dehydrogenase inhibitors to patients with isocitrate dehydrogenase-mutant glioma.
Neuro-oncology practice 12(Suppl 1), i29 - i37 () [10.1093/nop/npae100]  GO pmc  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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European standard clinical practice recommendations for paediatric high-grade gliomas
EJC paediatric oncology 5, 100210 () [10.1016/j.ejcped.2024.100210]  GO BibTeX | EndNote: XML, Text | RIS

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Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1-HER3 signaling.
Nature cancer nn, nn () [10.1038/s43018-024-00882-2]  GO BibTeX | EndNote: XML, Text | RIS

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Low- and High-Volume Disease in Metastatic Hormone-Sensitive Prostate Cancer: From CHAARTED to PSMA PET-An International Multicenter Retrospective Study.
Journal of nuclear medicine 66(1), 54 - 60 () [10.2967/jnumed.124.268441]  GO BibTeX | EndNote: XML, Text | RIS

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Genome-wide CRISPR-Cas 9 screens identify BCL family members as modulators of response to regorafenib in experimental glioma.
Neuro-Oncology nn, nn () [10.1093/neuonc/noae278]  GO BibTeX | EndNote: XML, Text | RIS

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Multi-omics profiling reveals key factors involved in Ewing sarcoma metastasis.
Molecular oncology nn, nn () [10.1002/1878-0261.13788]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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SARS-COV-2 Pre-Exposure Prophylaxis With Tixagevimab-Cilgavimab in Haematological, Immunocompromised Patients in the Omicron Era.
European journal of haematology nn, nn () [10.1111/ejh.14377]  GO BibTeX | EndNote: XML, Text | RIS

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Pulmonary Stereotactic Body Radiotherapy of Oligometastatic Head-and-Neck Squamous Cell Carcinoma - A multicenter retrospective study.
International journal of radiation oncology, biology, physics nn, nn () [10.1016/j.ijrobp.2024.12.015]  GO BibTeX | EndNote: XML, Text | RIS

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Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.
Acta Neuropathologica Communications 13(1), 4 () [10.1186/s40478-024-01921-w]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Genomic and phenotypic stability of fusion-driven pediatric sarcoma cell lines.
Nature Communications 16(1), 380 () [10.1038/s41467-024-55340-5]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Functional Characterization of Pathway Inhibitors for the Ubiquitin-Proteasome System (UPS) as Tool Compounds for CRBN and VHL-Mediated Targeted Protein Degradation.
ACS chemical biology nn, nn () [10.1021/acschembio.4c00450]  GO BibTeX | EndNote: XML, Text | RIS

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Potential for enhancing efficacy of screening colonoscopy by lowering starting ages and extending screening intervals: A modelling study for Germany.
International journal of cancer nn, nn () [10.1002/ijc.35322]  GO BibTeX | EndNote: XML, Text | RIS

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ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip
Nature genetics 57(1), 88-102 () [10.1038/s41588-024-02014-z]  GO BibTeX | EndNote: XML, Text | RIS

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In Regard to Ghirardelli et al
Practical Radiation Oncology 15(1), e90 - e91 () [10.1016/j.prro.2024.08.009]  GO BibTeX | EndNote: XML, Text | RIS

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Perioperative outcomes in an age-adapted analysis of the German StuDoQ|Pancreas registry for PDAC.
BMC surgery 25(1), 4 () [10.1186/s12893-024-02647-1]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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The sarcoma ring trial: a case-based analysis of inter-center agreement across 21 German-speaking sarcoma centers.
Journal of cancer research and clinical oncology 151(1), 30 () [10.1007/s00432-024-06063-z]  GO pmc  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Advances and challenges in precision imaging
The lancet / Oncology 26(1), e34 - e45 () [10.1016/S1470-2045(24)00395-4]  GO BibTeX | EndNote: XML, Text | RIS

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CXCR4-directed endoradiotherapy with [177Lu]Pentixather added to total body irradiation for myeloablative conditioning in patients with relapsed/refractory acute myeloid leukemia.
Theranostics 15(1), 19 - 29 () [10.7150/thno.101215]  GO DBCoverage  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival.
Autophagy nn, nn () [10.1080/15548627.2024.2443945]  GO BibTeX | EndNote: XML, Text | RIS

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Topical ruxolitinib for treatment-induced vitiligo in a patient with metastatic melanoma
JAAD case reports 55, 123 - 125 () [10.1016/j.jdcr.2024.11.002]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Predicting benefit from PARP inhibitors using deep learning on H&E-stained ovarian cancer slides.
European journal of cancer 216, 115199 () [10.1016/j.ejca.2024.115199]  GO BibTeX | EndNote: XML, Text | RIS

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Aspartate signalling drives lung metastasis via alternative translation.
Nature nn, nn () [10.1038/s41586-024-08335-7]  GO BibTeX | EndNote: XML, Text | RIS

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Predicting cisplatin tolerability in older adults with head and neck cancer - Insights for improved chemoradiation outcomes.
Radiotherapy and oncology 204, 110697 () [10.1016/j.radonc.2024.110697]  GO BibTeX | EndNote: XML, Text | RIS

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A retrospective, multicentric, nationwide analysis of the impact of splenectomy on survival of pancreatic cancer patients.
Langenbeck's archives of surgery 410(1), 14 () [10.1007/s00423-024-03570-y]  GO pmc  Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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MRgRT real-time target localization using foundation models for contour point tracking and promptable mask refinement.
Physics in medicine and biology 70(1), 015004 () [10.1088/1361-6560/ad9dad]  GO BibTeX | EndNote: XML, Text | RIS

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Panitumumab plus 5-fluorouracil and folinic acid or 5-fluorouracil and folinic acid alone as maintenance therapy in RAS wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212): final efficacy analysis of a randomised, open-label, phase 2 trial
EClinicalMedicine 79, 103004 () [10.1016/j.eclinm.2024.103004]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Impact of ALDH1A1 Expression in Intrahepatic Cholangiocellular Carcinoma
Journal of cancer 16(1), 1 - 11 () [10.7150/jca.99944]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Body Composition in Cholangiocarcinoma Affects Immune Cell Populations in the Tumor and Normal Liver Parenchyma
Journal of Clinical and Experimental Hepatology 15(2), 102460 () [10.1016/j.jceh.2024.102460]  GO BibTeX | EndNote: XML, Text | RIS

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Long-term outcomes among patients who respond within the first year to nivolumab plus ipilimumab or nivolumab monotherapy: A pooled analysis in 935 patients
European journal of cancer 214, 115119 () [10.1016/j.ejca.2024.115119]  GO BibTeX | EndNote: XML, Text | RIS