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Schadendorf, D. ; Dummer, R. ; Flaherty, K. T. ; Robert, C. ; Arance, A. ; de Groot, J. W. B. ; Garbe, C. ; Gogas, H. J. ; Gutzmer, R. ; Krajsová, I. ; Liszkay, L. ; Loquai, C. ; Mandalà, M. ; Yamazaki, N. ; Queirolo, P. ; Guenzel, C. ; Polli, A. ; Thakur, M. ; di Pietro, A. ; Ascierto, P. A.
A plain language summary of the 7-year update from part 1 of the COLUMBUS study: encorafenib and binimetinib for people with BRAF V600-mutant melanoma.
Future oncology nn, nn (2025) [10.1080/14796694.2024.2442851]2025
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Stubenvoll, A. ; Schmidt, M. ; Moeller, J. ; Chango, M. A. L. ; Schultz, C. ; Antoniadou, O. ; Loeffler-Wirth, H. ; Bernhart, S. ; Große, F. ; Thier, B. ; Paschen, A. ; Anderegg, U. ; Simon, J. C. ; Ziemer, M. ; Schoeder, C. T. ; Binder, H. ; Kunz, M.
Single-cell transcriptomics and epigenomics point to CD58-CD2 interaction in controlling primary melanoma growth and immunity.
Cancer communications nn, nn (2025) [10.1002/cac2.12651]2025
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Egea-Rodriguez, S. ; Váraljai, R. ; Nordmann, T. M. ; Lubis, R. ; Philip, M. ; Rambow, F. ; Roesch, A. ; Flaig, M. ; Horn, S. ; Stoll, R. ; Zhao, F. ; Paschen, A. ; Klebl, B. ; Hickson, I. D. ; Schadendorf, D. ; Mann, M. ; Helfrich, I.
RECQL4 affects MHC class II-mediated signalling and favours an immune-evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma.
Clinical and translational medicine 15(1), e70094 (2025) [10.1002/ctm2.70094]2025
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Burkhard-Meier, A. ; Rechenauer, V. V. ; Berclaz, L. M. ; Jurinovic, V. ; Albertsmeier, M. ; Dürr, H. R. ; Güler, S. E. ; Hoberger, M. ; Klein, A. ; Knösel, T. ; Kunz, W. G. ; Schmidt-Hegemann, N.-S. ; Von Bergwelt-Baildon, M. ; Lindner, L. H. ; Di Gioia, D.
Maintenance treatment with trofosfamide in patients with advanced soft tissue sarcoma - a retrospective single-centre analysis.
Acta oncologica 64, 56 - 62 (2025) [10.2340/1651-226X.2025.42356]2025
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Neugebauer, E. ; Walter, S. ; Tan, J. ; Drayman, N. ; Franke, V. ; van Gent, M. ; Pennisi, S. ; Veratti, P. ; Stein, K. S. ; Welker, I. ; Tay, S. ; Verjans, G. M. G. M. ; Timmers, H. T. M. ; Akalin, A. ; Landthaler, M. ; Ensser, A. ; Wyler, E. ; Full, F.
Herpesviruses mimic zygotic genome activation to promote viral replication.
Nature Communications 16(1), 710 (2025) [10.1038/s41467-025-55928-5]2025
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Rüfer, A. ; Nilius, H. ; Hermine, O. ; Niedoszytko, M. ; Oude Elberink, J. N. G. ; Bonadonna, P. ; Shoumariyeh, K. ; Gulen, T. ; Hartmann, K. ; Sabato, V. ; Angelova-Fischer, I. ; Baffoe, D. ; Christen, D. ; Belloni Fortina, A. ; Breynaert, C. ; Brockow, K. ; von Bubnoff, N. ; Bumbea, H. ; van Daele, P. ; Doubek, M. ; Dybedal, I. ; Elena, C. ; Fokoloros, C. ; Górska, A. ; Heizmann, M. ; Jentzsch, M. ; Klein, S. ; Lübke, J. ; Mattsson, M. ; Mulder, A. ; Panse, J. ; Schug, T. D. ; Sciumè, M. ; Stefan, A. ; Sztormowska, M. ; Várkonyi, J. ; Wortmann, F. ; Yavuz, A. S. ; Sperr, M. ; Gotlib, J. ; Reiter, A. ; Triggiani, M. ; Sperr, W. R. ; Valent, P.
Prognostic impact of expression of CD2, CD25, and/or CD30 in/on mast cells in systemic mastocytosis: a registry study of the European Competence Network on Mastocytosis.
Leukemia nn, nn (2025) [10.1038/s41375-024-02504-3]2025
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Tauziède-Espariat, A. ; Simbozel, M. ; Sievers, P. ; Dangouloff-Ros, V. ; Guida, L. ; Blauwblomme, T. ; Beccaria, K. ; Saffroy, R. ; Hasty, L. ; Métais, A. ; Grill, J. ; Guerrini-Rousseau, L. ; Varlet, P.
Pediatric high-grade gliomas with concomitant RB1 and SETD2 alterations and Li-Fraumeni syndrome.
Acta Neuropathologica Communications 13(1), 8 (2025) [10.1186/s40478-024-01885-x]2025
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Hofmann, F. O. ; Sirtl, S. ; Heiliger, C. ; Werner, J.
Patientensicherheit in der palliativen Chirurgie.
Die Chirurgie nn, nn (2025) [10.1007/s00104-024-02202-x]2025
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Büttner, M. ; Böke, S. ; Baumeister, S. ; Bachmann, R. ; Bitzer, M. ; Bösmüller, H. ; Wichmann, D. ; Niyazi, M. ; Gani, C.
Simultaneous integrated boost to lateral pelvic lymph nodes during chemoradiotherapy in high-risk rectal cancer.
Strahlentherapie und Onkologie nn, nn (2025) [10.1007/s00066-024-02354-z]2025
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Stock, S. ; Bücklein, V. L. ; Blumenberg, V. ; Magno, G. ; Emhardt, A.-J. ; Holzem, A. M. E. ; Cordas Dos Santos, D. M. ; Schmidt, C. ; Grießhammer, S. ; Frölich, L. ; Kobold, S. ; von Bergwelt-Baildon, M. ; Rejeski, K. ; Subklewe, M.
Prognostic significance of immune reconstitution following CD19 CAR T-cell therapy for relapsed/refractory B-cell lymphoma.
HemaSphere 9(1), e70062 (2025) [10.1002/hem3.70062]2025
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Priego, N. ; de Pablos-Aragoneses, A. ; Perea-García, M. ; Pieri, V. ; Hernández-Oliver, C. ; Álvaro-Espinosa, L. ; Rojas, A. ; Sánchez, O. ; Steindl, A. ; Caleiras, E. ; García, F. ; García-Martín, S. ; Graña-Castro, O. ; García-Mulero, S. ; Serrano, D. ; Velasco-Beltrán, P. ; Jiménez-Lasheras, B. ; Egia-Mendikute, L. ; Rupp, L. ; Stammberger, A. ; Meinhardt, M. ; Chaachou-Charradi, A. ; Martínez-Saez, E. ; Bertero, L. ; Cassoni, P. ; Mangherini, L. ; Pellerino, A. ; Rudà, R. ; Soffietti, R. ; Al-Shahrour, F. ; Saftig, P. ; Sanz-Pamplona, R. ; Schmitz, M. ; Crocker, S. J. ; Calvo, A. ; Palazón, A. ; RENACER (Collaboration Author) ; Valiente, M.
TIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells.
Cancer discovery 15(1), 179 - 201 (2025) [10.1158/2159-8290.CD-24-0134]2025
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Schorn, S. ; Fritz, A. ; Kaissis, G. ; Gaida, M. M. ; Steiger, K. ; Jäger, C. ; Schlitter, A. M. ; Braren, R. ; Friess, H. ; Demir, I. E. ; Ceyhan, G. O.
Neural invasion severity is a strong predictor of local recurrence in pancreatic ductal adenocarcinoma.
Surgery 180, 109018 (2025) [10.1016/j.surg.2024.109018]2025
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Erickson, N. ; Sulosaari, V. ; Sullivan, E. S. ; Laviano, A. ; van Ginkel-Res, A. ; Remijnse, W. ; Wesseling, J. ; Koepcke, U. ; Weber, N. ; Huebner, J. ; Mathies, V. ; Theurich, S. ; Fey, T.
Nutrition Care in Cancer: An Overlooked Part of Patient-Centered Care.
Seminars in oncology nursing nn, nn (2025) [10.1016/j.soncn.2024.151799]2025
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Brenner, H. (First author) ; Holland-Letz, T. ; Hoffmeister, M. ; Heisser, T. (Last author)
Accounting for differential exclusions in the NordICC trial discloses stronger-than-reported effects of screening colonoscopy.
Journal of clinical epidemiology nn, nn (2025) [10.1016/j.jclinepi.2025.111669]2025
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Westphalen, C. B.
Unveiling Targets and Resistance in FGFR-Altered Cancers.
Annals of oncology nn, nn (2025) [10.1016/j.annonc.2025.01.002]2025
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Ni, Y. ; Wu, J. ; Liu, F. ; Yi, Y. ; Meng, X. ; Gao, X. ; Xiao, L. ; Zhou, W. ; Chen, Z. ; Chu, P. ; Xing, D. ; Yuan, Y. ; Ding, D. ; Shen, G. ; Yang, M. ; Wu, R. ; Wang, L. ; Melo, L. M. N. ; Lin, S. ; Cheng, X. ; Li, G. ; Tasdogan, A. ; Ubellacker, J. M. ; Zhao, H. ; Fang, S. ; Shen, B.
Deep imaging of LepR+ stromal cells in optically cleared murine bone hemisections.
Bone research 13(1), 6 (2025) [10.1038/s41413-024-00387-9]2025
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Venkataramani, V. (First author) ; Yang, Y. ; Ille, S. ; Suchorska, B. ; Loges, S. ; Tost, H. ; Sahm, F. ; Pfister, S. ; Trumpp, A. ; Krieg, S. M. ; Kuner, T. ; Wick, W. ; Winkler, F. (Last author)
Cancer Neuroscience of Brain Tumors: From Multicellular Networks to Neuroscience-Instructed Cancer Therapies.
Cancer discovery 15(1), 39 - 51 (2025) [10.1158/2159-8290.CD-24-0194]2025
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Ribrag, V. ; Iglesias, L. ; De Braud, F. ; Ma, B. ; Yokota, T. ; Zander, T. ; Spreafico, A. ; Subbiah, V. ; Illert, A. L. ; Tan, D. ; Santoro, A. ; Munster, P. N. ; Suehiro, Y. ; Wang, Y. ; Ji, D.-M. ; Chen, S. ; Beltz, K. ; Suenaga, N. ; Ramkumar, T. ; Luo, F. ; Lai, C. ; Wainberg, Z. A.
A first-in-human phase 1/2 dose-escalation study of MAK683 (EED inhibitor) in patients with advanced malignancies.
European journal of cancer 216, 115122 (2025) [10.1016/j.ejca.2024.115122]2025
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Kerle, I. ; Gross, T. ; Kögler, A. ; Arnold, J. ; Werner, M. ; Eckardt, J.-N. ; Möhrmann, E. E. ; Arlt, M. ; Hutter, B. ; Hüllein, J. ; Richter, D. ; Schneider, M. M. K. ; Hlevnjak, M. ; Möhrmann, L. ; Hanf, D. ; Heilig, C. ; Kreutzfeldt, S. ; Teleanu, M.-V. ; Schröck, E. ; Hübschmann, D. ; Horak, P. ; Heining, C. ; Fröhling, S. ; Glimm, H.
Translational and clinical comparison of whole genome and transcriptome to panel sequencing in precision oncology.
npj precision oncology 9(1), 9 (2025) [10.1038/s41698-024-00788-3]2025
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Kersting, D. ; Borys, K. ; Küper, A. ; Kim, M. ; Haubold, J. ; Goerttler, T. ; Umutlu, L. ; Costa, P. F. ; Kleesiek, J. ; Rischpler, C. ; Nensa, F. ; Herrmann, K. ; Fendler, W. P. ; Weber, M. ; Hosch, R. ; Seifert, R.
Staging of prostate Cancer with ultra-fast PSMA-PET scans enhanced by AI.
European journal of nuclear medicine and molecular imaging nn, nn (2025) [10.1007/s00259-024-07060-7]2025
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Abdullah, A. ; Kumbrink, J. ; Liokatis, P. ; Mock, A. ; Abdullah, A. ; Dewenter, I. ; Obermeier, K. T.
The Role of Glucose-6-Phosphate Dehydrogenase in Skin Cancer Metabolism: A Paradigm Shift in Treatment Approaches.
Cancers 17(1), 48 (2025) [10.3390/cancers17010048]2025
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Stork, T. ; Ranft, A. ; Aigner, C. ; Jurgens, H. ; Ladenstein, R. L. ; Timmermann, B. ; Van den Berg, H. ; Dirksen, U. ; Collaud, S.
Primary Mediastinal Ewing's Sarcoma: Post Hoc Analysis from Two International Multicenter Prospective Randomized Trials.
Cancers 17(1), 118 (2025) [10.3390/cancers17010118]2025
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Haller, V. ; Reiff, C. ; Hamacher, R. ; Kostbade, K. ; Kaths, M. ; Treckmann, J. ; Bertram, S. ; Zaun, Y. ; Bauer, S. ; Falkenhorst, J.
Correction: Overall survival of patients with KIT-mutant metastatic GIST in the era of multiple kinase inhibitor availability.
Journal of cancer research and clinical oncology 151(1), 33 (2025) [10.1007/s00432-024-06056-y]2025
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Guberina, N. ; Guberina, M. ; Alberti, Y. ; Stuschke, M.
Definitive Radiochemotherapie des Ösophaguskarzinoms: etablierte Therapie und neue StandardsDefinitive radiochemotherapy of esophageal cancer: established treatment and new standards
Die Onkologie nn, nn (2025) [10.1007/s00761-024-01645-5]2025
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Lazaro-Navarro, J. ; Alcon, C. ; Dorel, M. ; Alasfar, L. ; Bastian, L. ; Baldus, C. ; Astrahantseff, K. ; Yaspo, M.-L. ; Montero, J. ; Eckert, C.
Inhibiting H3K27 Demethylases Downregulates CREB-CREBBP, Overcoming Resistance in Relapsed Acute Lymphoblastic Leukemia.
Cancer medicine 14(1), 1 - 7 (2025) [10.1002/cam4.70596]2025
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Schiele, P. ; Kolling, S. ; Rosnev, S. ; Junkuhn, C. ; Walter, A. L. ; von Einem, J. C. ; Stintzing, S. ; Schöning, W. ; Sauer, I. M. ; Modest, D. P. ; Heinrich, K. ; Weiss, L. ; Heinemann, V. ; Bullinger, L. ; Frentsch, M. ; Na, I.-K.
Flow Cytometric Assessment of FcγRIIIa-V158F Polymorphisms and NK Cell Mediated ADCC Revealed Reduced NK Cell Functionality in Colorectal Cancer Patients.
Cells 14(1), 32 (2025) [10.3390/cells14010032]2025
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Trapp, C. ; Schmidt-Hegemann, N. ; Keilholz, M. ; Brose, S. F. ; Marschner, S. N. ; Schönecker, S. ; Maier, S. H. ; Dehelean, D.-C. ; Rottler, M. ; Konnerth, D. ; Belka, C. ; Corradini, S. ; Rogowski, P.
Patient- and clinician-based evaluation of large language models for patient education in prostate cancer radiotherapy.
Strahlentherapie und Onkologie nn, nn (2025) [10.1007/s00066-024-02342-3]2025
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Warmbrunn, J. ; Straube, C. ; Haase, H.-U. ; Sinnecker, D. ; Laugwitz, K.-L. ; Combs, S. E. ; Schneider, S. ; Habermehl, D.
Influence of radiotherapy on cardiac implantable devices and leads-a single-institution analysis and critical evaluation of current guidelines.
Strahlentherapie und Onkologie nn, nn (2025) [10.1007/s00066-024-02345-0]2025
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Piroth, M. D. ; Krug, D. ; Baumann, R. ; Strnad, V. ; Borm, K. ; Combs, S. ; Corradini, S. ; Duma, M. N. ; Dunst, J. ; Fastner, G. ; Feyer, P. ; Fietkau, R. ; Harms, W. ; Hehr, T. ; Hörner-Rieber, J. ; Matuschek, C. ; Schmeel, C. ; Budach, W. ; Oncology, B. C. E. P. o. t. G. S. o. R. (Collaboration Author)
Implant-based reconstruction and adjuvant radiotherapy in breast cancer patients-current status and DEGRO recommendations.
Strahlentherapie und Onkologie nn, nn (2025) [10.1007/s00066-024-02334-3]2025
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Zirngibl, F. ; Gebert, P. ; Materne, B. ; Launspach, M. ; Künkele, A. ; Hundsdoerfer, P. ; Cyrull, S. ; Deubzer, H. E. ; Kühl, J.-S. ; Eggert, A. ; Lang, P. ; Oevermann, L. ; von Stackelberg, A. ; Schulte, J.
Everolimus with or without mycophenolate mofetil for GVHD prophylaxis after allogeneic HSCT in children with acute kidney injury - a single-center retrospective analysis.
Transplantation and cellular therapy nn, nn (2025) [10.1016/j.jtct.2025.01.002]2025
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Bourdier, S. ; Fisch, A.-S. ; Alp, K. M. ; Das, R. ; Mertins, P. ; Tinhofer, I.
High Ano1 expression as key driver of resistance to radiation and cisplatin in HPV-negative head and neck squamous cell carcinoma.
Scientific reports 15(1), 1555 (2025) [10.1038/s41598-025-85214-9]2025
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Safizadeh, F. (First author) ; Mandic, M. ; Hoffmeister, M. ; Brenner, H. (Last author)
To what extent is the association between obesity and colorectal cancer risk mediated by systemic inflammation?
Cancer communications nn, nn (2025) [DOI:10.1002/cac2.12659]2025
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Stanger, A. M. ; Arnone, M. ; Hanns, P. ; Kimmich, L. M. ; Kübler, J. ; Gekeler, S. ; Görsch, E. S. ; Kramer, L. ; Baer, M. ; Schroeder, J. C. ; Mills, T. S. ; Konantz, M. ; Rudat, S. ; Lengerke, C.
Recipient sex and donor leukemic cell characteristics determine leukemogenesis in patient-derived models.
Haematologica nn, nn (2025) [10.3324/haematol.2023.284647]2025
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Zu, F. ; Chen, C. ; Geng, Q. ; Li, H. ; Chan, B. ; Luo, G. ; Wu, M. ; Ilmer, M. ; Renz, B. W. ; Bentum-Ennin, L. ; Gu, H. ; Sheng, W.
Smad2 Cooperating with TGIF2 Contributes to EMT and Cancer Stem Cells Properties in Pancreatic Cancer via Co-Targeting SOX2.
International journal of biological sciences 21(2), 524 - 543 (2025) [10.7150/ijbs.102381]2025
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Foltyn-Dumitru, M. ; Rastogi, A. ; Cho, J. ; Schell, M. ; Mahmutoglu, M. A. ; Kessler, T. ; Sahm, F. ; Wick, W. ; Bendszus, M. ; Brugnara, G. ; Vollmuth, P. (Last author)
The potential of GPT-4 advanced data analysis for radiomics-based machine learning models.
Neuro-oncology advances 7(1), vdae230 (2025) [10.1093/noajnl/vdae230]2025
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Müller, J. ; Bayer, F. P. ; Wilhelm, M. ; Schuh, M. G. ; Kuster, B. ; The, M.
PTMNavigator: interactive visualization of differentially regulated post-translational modifications in cellular signaling pathways.
Nature Communications 16(1), 510 (2025) [10.1038/s41467-024-55533-y]2025
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Hoffmann, S. ; Hoffmann, T. ; Potkrajcic, V. ; Deinzer, C. K. W. ; Benzler, K. ; Zender, L. ; Daigeler, A. ; Thiel, J. T.
SarkoLife: quality of life in patients undergoing multimodal soft tissue sarcoma treatment.
World journal of surgical oncology 23(1), 10 (2025) [10.1186/s12957-024-03632-x]2025
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Landry, A. P. ; Wang, J. Z. ; Liu, J. ; Patil, V. ; Gui, C. ; Patel, Z. ; Ajisebutu, A. ; Ellenbogen, Y. ; Wei, Q. ; Singh, O. ; Sosa, J. ; Mansouri, S. ; Wilson, C. ; Cohen-Gadol, A. A. ; Zaazoue, M. A. ; Tabatabai, G. ; Tatagiba, M. ; Behling, F. ; Barnholtz-Sloan, J. S. ; Sloan, A. E. ; Chotai, S. ; Chambless, L. B. ; Rebchuk, A. D. ; Makarenko, S. ; Yip, S. ; Mansouri, A. ; Tsang, D. S. ; Aldape, K. ; Gao, A. ; Meningiomas, I. C. o. (Collaboration Author) ; Nassiri, F. ; Zadeh, G.
Development and validation of a molecular classifier of meningiomas.
Neuro-Oncology nn, nn (2025) [10.1093/neuonc/noae242]2025
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Roth, P. ; Capper, D. ; Calabrese, E. ; Halasz, L. M. ; Jakola, A. S.
Role of the tumor board when prescribing mutant isocitrate dehydrogenase inhibitors to patients with isocitrate dehydrogenase-mutant glioma.
Neuro-oncology practice 12(Suppl 1), i29 - i37 (2025) [10.1093/nop/npae100]2025
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Szychot, E. ; Giraud, G. ; Hargrave, D. ; van Vuurden, D. ; Grill, J. ; Biassoni, V. ; Massimo, M. ; Von Büren, A. O. ; Kebudi, R. ; Gil-da-Costa, M. J. ; van Zanten, S. V. ; Bailey, S. ; Karremann, M. ; Bolle, S. ; Ajithkumar, T. ; Krause, M. ; Lassen-Ramshad, Y. ; Janssens, G. ; Morana, G. ; Löbel, U. ; Avula, S. ; Bison, B. ; Lequin, M. ; Aquilina, K. ; Thomale, U. ; Nilsson, P. ; Hamdeh, S. B. A. ; Pietsch, T. ; Varlet, P. ; Jacques, T. S. ; Wesseling, P. ; Jones, D. ; Tabori, U. ; Das, A. ; Mulligan, D. ; Kozmann, F. ; Kramm, C. M.
European standard clinical practice recommendations for paediatric high-grade gliomas
EJC paediatric oncology 5, 100210 (2025) [10.1016/j.ejcped.2024.100210]2025
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Würth, R. (First author) ; Donato, E. (First author) ; Michel, L. L. ; Saini, M. (First author) ; Becker, L. (First author) ; Cheytan, T. ; Doncevic, D. ; Messmer, T. ; Gutjahr, E. ; Weber, R. ; Klein, C. ; Alborzinia, H. ; Yildiz, U. ; Vogel, V. ; Hlevnjak, M. ; Kozyulina, P. ; Neuberth, S.-J. ; Schwerd-Kleine, P. ; Jakab, S. ; Pfarr, N. ; Angeles, A. ; Laut, A. ; Karpova, D. ; Falcone, M. ; Hardt, O. ; Theek, B. ; Wagner, C. V. ; Becker, M. ; Wagner, S. ; Haselmayr, M. ; Schmitt, A. ; Müller-Tidow, C. ; Riethdorf, S. ; Pantel, K. ; Zapatka, M. ; Sültmann, H. ; Herrmann, C. ; Thewes, V. ; Lichter, P. ; Schneeweiss, A. ; Sprick, M. (Last author) ; Trumpp, A. (Last author)
Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1-HER3 signaling.
Nature cancer nn, nn (2025) [10.1038/s43018-024-00882-2]2025
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Unterrainer, L. M. ; Hope, T. A. ; Fendler, W. P. ; Grogan, T. ; Ndlovu, H. ; Armstrong, W. ; Barbato, F. ; Benz, M. R. ; Rettig, M. B. ; Kishan, A. U. ; Sathekge, M. ; Herrmann, K. ; Czernin, J. ; Calais, J.
Low- and High-Volume Disease in Metastatic Hormone-Sensitive Prostate Cancer: From CHAARTED to PSMA PET-An International Multicenter Retrospective Study.
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Haeusser, L. A. ; Becker, H. ; Kuhlburger, L. ; Zago, M. ; Walter, B. ; Tsiami, F. ; Erdmann, S. ; Trampert, J. ; Surender, S. ; Stahl, A. ; Templin, M. ; Wegner, E. ; Schmidt, T. ; Schmees, C. ; Casadei, N. ; Sevenich, L. ; Claassen, M. ; Nahnsen, S. ; Beck, S. ; Merk, D. J. ; Tabatabai, G.
Genome-wide CRISPR-Cas 9 screens identify BCL family members as modulators of response to regorafenib in experimental glioma.
Neuro-Oncology nn, nn (2025) [10.1093/neuonc/noae278]2025
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Chicón-Bosch, M. ; Sánchez-Serra, S. ; Rosàs-Lapeña, M. ; Costa-Fraga, N. ; Besalú-Velázquez, J. ; Illa-Bernadí, J. ; Mateo-Lozano, S. ; Cidre-Aranaz, F. ; Grünewald, T. G. P. ; Díaz-Lagares, Á. ; Lopez-Alemany, R. ; Tirado, Ò. M.
Multi-omics profiling reveals key factors involved in Ewing sarcoma metastasis.
Molecular oncology nn, nn (2025) [10.1002/1878-0261.13788]2025
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Hoechstetter, M. A. ; Hollwich, E.-M. ; Illner, D. ; Pham, T.-T. ; von Bergwelt-Baildon, M. ; Dreyling, M. ; Wendtner, C.-M.
SARS-COV-2 Pre-Exposure Prophylaxis With Tixagevimab-Cilgavimab in Haematological, Immunocompromised Patients in the Omicron Era.
European journal of haematology nn, nn (2025) [10.1111/ejh.14377]2025
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Nägler, F. ; Vorbach, S. ; Mohamed, A. A. ; Thaqi, S. ; Adebahr, S. ; Ehret, F. ; Kraft, J. ; Fabian, A. ; Weissmann, T. ; Kaufmann, J. ; Drabke, S. ; Looman, E. L. ; Waltenberger, M. ; Kraus, K. M. ; Grohmann, M. ; Dehl, K. ; Rogers, S. ; Gawish, A. ; Becker, J.-N. ; Klement, R. J. ; Partl, R. ; Trommer, M. ; Grosu, A.-L. ; Rimner, A. ; Gkika, E. ; Riesterer, O. ; Putz, F. ; Ganswindt, U. ; Moustakis, C. ; Nicolay, N. H. ; Brunner, T. B. ; Blanck, O. ; Wittig-Sauerwein, A. ; Balermpas, P. ; Rühle, A.
Pulmonary Stereotactic Body Radiotherapy of Oligometastatic Head-and-Neck Squamous Cell Carcinoma - A multicenter retrospective study.
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Okonechnikov, K. (First author) ; Ghasemi, D. R. ; Schrimpf, D. ; Tonn, S. ; Mynarek, M. ; Koster, J. ; Milde, T. ; Zheng, T. ; Sievers, P. ; Sahm, F. ; Jones, D. T. W. ; von Deimling, A. ; Pfister, S. M. ; Kool, M. ; Pajtler, K. W. ; Korshunov, A. (Last author)
Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.
Acta Neuropathologica Communications 13(1), 4 (2025) [10.1186/s40478-024-01921-w]2025
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Kasan, M. (First author) ; Geyer, F. ; Siebenlist, J. ; Sill, M. ; Öllinger, R. ; Faehling, T. ; de Álava, E. ; Surdez, D. ; Dirksen, U. ; Oehme, I. ; Scotlandi, K. ; Delattre, O. ; Müller-Nurasyid, M. ; Rad, R. ; Strauch, K. ; Grünewald, T. ; Cidre-Aranaz, F. (Last author)
Genomic and phenotypic stability of fusion-driven pediatric sarcoma cell lines.
Nature Communications 16(1), 380 (2025) [10.1038/s41467-024-55340-5]2025
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Schwalm, M. P. ; Menge, A. ; Elson, L. ; Greco, F. A. ; Robers, M. B. ; Müller, S. ; Knapp, S.
Functional Characterization of Pathway Inhibitors for the Ubiquitin-Proteasome System (UPS) as Tool Compounds for CRBN and VHL-Mediated Targeted Protein Degradation.
ACS chemical biology nn, nn (2025) [10.1021/acschembio.4c00450]2025
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Sergeev, D. (First author) ; Heisser, T. ; Hoffmeister, M. ; Brenner, H. (Last author)
Potential for enhancing efficacy of screening colonoscopy by lowering starting ages and extending screening intervals: A modelling study for Germany.
International journal of cancer nn, nn (2025) [10.1002/ijc.35322]2025
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Lee, J. J. Y. ; Tao, R. ; You, Z. ; et al
ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip
Nature genetics 57(1), 88-102 (2025) [10.1038/s41588-024-02014-z]2025
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Shin, J. Y. ; Rimner, A. ; Simone, C. B.
In Regard to Ghirardelli et al
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Tschaidse, T. ; Hofmann, F. O. ; Renz, B. ; Hungbauer, M. ; Klinger, C. ; Buhr, H. J. ; Uhl, W. ; Mees, S. T. ; Keck, T. ; Reissfelder, C. ; Ghadimi, M. ; D'Haese, J. G. ; Werner, J. ; Ilmer, M.
Perioperative outcomes in an age-adapted analysis of the German StuDoQ|Pancreas registry for PDAC.
BMC surgery 25(1), 4 (2025) [10.1186/s12893-024-02647-1]2025
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Roohani, S. ; Handtke, J. ; Hummedah, K. ; et al
The sarcoma ring trial: a case-based analysis of inter-center agreement across 21 German-speaking sarcoma centers.
Journal of cancer research and clinical oncology 151(1), 30 (2025) [10.1007/s00432-024-06063-z]2025
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Hricak, H. ; Mayerhoefer, M. E. ; Herrmann, K. ; Lewis, J. S. ; Pomper, M. G. ; Hess, C. P. ; Riklund, K. ; Scott, A. M. ; Weissleder, R.
Advances and challenges in precision imaging
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Braitsch, K. ; Lorenzini, T. ; Hefter, M. ; Koch, K. ; Nickel, K. ; Peeken, J. C. ; Götze, K. S. ; Weber, W. ; Allmann, A. ; D'Alessandria, C. ; Brosch-Lenz, J. ; Bassermann, F. ; Rudelius, M. ; Verbeek, M. ; Eiber, M. ; Herhaus, P.
CXCR4-directed endoradiotherapy with [177Lu]Pentixather added to total body irradiation for myeloablative conditioning in patients with relapsed/refractory acute myeloid leukemia.
Theranostics 15(1), 19 - 29 (2025) [10.7150/thno.101215]2025
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Zein, L. ; Dietrich, M. ; Balta, D. ; Bader, V. ; Scheuer, C. ; Zellner, S. ; Weinelt, N. ; Vandrey, J. ; Mari, M. C. ; Behrends, C. ; Zunke, F. ; Winklhofer, K. F. ; van Wijk, S.
Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival.
Autophagy nn, nn (2025) [10.1080/15548627.2024.2443945]2025
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Tasdogan, A. ; Schadendorf, D. ; Ugurel, S.
Topical ruxolitinib for treatment-induced vitiligo in a patient with metastatic melanoma
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Marmé, F. ; Krieghoff-Henning, E. I. ; Kiehl, L. ; Wies, C. ; Hauke, J. ; Hahnen, E. ; Harter, P. ; Schouten, P. C. ; Brodkorb, T. ; Kayali, M. ; Heitz, F. ; Zamagni, C. ; González-Martin, A. ; Treilleux, I. ; Kommoss, S. ; Prieske, K. ; Gaiser, T. ; Fröhling, S. ; Ray-Coquard, I. ; Pujade-Lauraine, E. ; Brinker, T. (Last author)
Predicting benefit from PARP inhibitors using deep learning on H&E-stained ovarian cancer slides.
European journal of cancer 216, 115199 (2025) [10.1016/j.ejca.2024.115199]2025
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Doglioni, G. ; Fernández-García, J. ; Igelmann, S. ; Altea-Manzano, P. ; Blomme, A. ; La Rovere, R. ; Liu, X.-Z. ; Liu, Y. ; Tricot, T. ; Nobis, M. ; An, N. ; Leclercq, M. ; El Kharraz, S. ; Karras, P. ; Hsieh, Y.-H. ; Solari, F. A. ; Martins Nascentes Melo, L. ; Allies, G. ; Scopelliti, A. ; Rossi, M. ; Vermeire, I. ; Broekaert, D. ; Ferreira Campos, A. M. ; Neven, P. ; Maetens, M. ; Van Baelen, K. ; Alkan, H. F. ; Planque, M. ; Floris, G. ; Sickmann, A. ; Tasdogan, A. ; Marine, J.-C. ; Scheele, C. L. G. J. ; Desmedt, C. ; Bultynck, G. ; Close, P. ; Fendt, S.-M.
Aspartate signalling drives lung metastasis via alternative translation.
Nature nn, nn (2025) [10.1038/s41586-024-08335-7]2025
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Rühle, A. ; Weymann, M. ; Behrens, M. ; Olbrich, J. ; Kut, C. ; Marschner, S. N. ; Haderlein, M. ; Fabian, A. ; Senger, C. ; Bakst, B. P. ; Kraft, J. ; von der Grün, J. ; Looman, E. L. ; Chen, E. ; Domschikowski, J. ; Altay-Langguth, A. ; Kalinauskaite, G. ; Lewitzki, V. ; Bonomi, M. ; Blakaj, D. ; Jhawar, S. R. ; Baliga, S. ; Elguindy, A. N. ; Ferentinos, K. ; Zamboglou, C. ; Müller, J. A. ; Leucht, C. ; Dickstein, D. R. ; Schnellhardt, S. ; Haehl, E. ; Hambsch, P. ; Kuhnt, T. ; Seidel, C. ; Belka, C. ; Mayer, A. ; Schmidberger, H. ; Grosu, A.-L. ; Balermpas, P. ; Stromberger, C. ; Binder, H. ; Quon, H. ; Nicolay, N. H.
Predicting cisplatin tolerability in older adults with head and neck cancer - Insights for improved chemoradiation outcomes.
Radiotherapy and oncology 204, 110697 (2025) [10.1016/j.radonc.2024.110697]2025
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Kießler, M. ; Jäger, C. ; Mota Reyes, C. ; Pergolini, I. ; Schorn, S. ; Göß, R. ; Safak, O. ; Martignoni, M. E. ; Novotny, A. R. ; Uhl, W. ; Werner, J. ; Ghadimi, M. ; Hartwig, W. ; Ruppert, R. ; Keck, T. ; Bruns, C. J. ; Oldhafer, K.-J. ; Schnitzbauer, A. ; Germer, C.-T. ; Sommer, F. ; Mees, S. T. ; Brunner, M. ; Köninger, J. ; Glowka, T. R. ; Kalff, J. C. ; Reißfelder, C. ; Bartsch, D. K. ; Kraus, T. ; Padberg, W. ; Piso, P. ; Lammers, B. J. ; Rudolph, H. ; Moench, C. ; Farkas, S. ; Friess, H. ; Ceyhan, G. O. ; Demir, I. E.
A retrospective, multicentric, nationwide analysis of the impact of splenectomy on survival of pancreatic cancer patients.
Langenbeck's archives of surgery 410(1), 14 (2025) [10.1007/s00423-024-03570-y]2025
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Blöcker, T. ; Lombardo, E. ; Marschner, S. N. ; Belka, C. ; Corradini, S. ; Palacios, M. A. ; Riboldi, M. ; Kurz, C. ; Landry, G.
MRgRT real-time target localization using foundation models for contour point tracking and promptable mask refinement.
Physics in medicine and biology 70(1), 015004 (2025) [10.1088/1361-6560/ad9dad]2025
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Stahler, A. ; Karthaus, M. ; Fruehauf, S. ; Graeven, U. ; Müller, L. ; Fischer von Weikersthal, L. ; Caca, K. ; Goekkurt, E. ; Ballhausen, A. ; Sommerhäuser, G. ; Alig, A. H. S. ; Held, S. ; Jarosch, A. ; Horst, D. ; Reinacher-Schick, A. ; Kasper, S. ; Heinemann, V. ; Stintzing, S. ; Trarbach, T. ; Modest, D. P.
Panitumumab plus 5-fluorouracil and folinic acid or 5-fluorouracil and folinic acid alone as maintenance therapy in RAS wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212): final efficacy analysis of a randomised, open-label, phase 2 trial
EClinicalMedicine 79, 103004 (2025) [10.1016/j.eclinm.2024.103004]2025
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Kurowski, K. ; Föll, M. ; Werner, T. ; Schilling, O. ; Werner, M. ; Fichtner-Feigl, S. ; Bengsch, B. ; Bronsert, P. ; Holzner, P. A. ; Timme, S.
Impact of ALDH1A1 Expression in Intrahepatic Cholangiocellular Carcinoma
Journal of cancer 16(1), 1 - 11 (2025) [10.7150/jca.99944]2025
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Wang, G. ; Liu, D. ; Al-Masri, T. M. ; Otto, C. C. ; Siveke, J. ; Lang, S. A. ; Ulmer, T. F. ; Olde Damink, S. W. ; Luedde, T. ; Dahl, E. ; Neumann, U. P. ; Heij, L. R. ; Bednarsch, J.
Body Composition in Cholangiocarcinoma Affects Immune Cell Populations in the Tumor and Normal Liver Parenchyma
Journal of Clinical and Experimental Hepatology 15(2), 102460 (2025) [10.1016/j.jceh.2024.102460]2025
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Robert, C. ; Long, G. V. ; Larkin, J. ; Wolchok, J. D. ; Hassel, J. C. ; Schadendorf, D. ; Hodi, F. S. ; Lebbé, C. ; Grob, J.-J. ; Hyngstrom, J. R. ; Wagstaff, J. ; Chesney, J. ; Butler, M. O. ; Bechter, O. ; Márquez-Rodas, I. ; Pavlick, A. C. ; Durani, P. ; Pe Benito, M. ; Wang, P. ; Postow, M. A. ; Ascierto, P. A.
Long-term outcomes among patients who respond within the first year to nivolumab plus ipilimumab or nivolumab monotherapy: A pooled analysis in 935 patients
European journal of cancer 214, 115119 (2025) [10.1016/j.ejca.2024.115119]2025
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