DKTK Publications

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Hemizygous deletion of CDKN2A/B in IDH-mutated glioma: Prognostic impact when adjusting for clinical factors.
Neuro-oncology advances 8(1), vdag096 () [10.1093/noajnl/vdag096]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Familial risks in prostate cancer between brothers and half-brothers as clues to germline genetic and environmental causes.
Familial cancer 25(2), 51 () [10.1007/s10689-026-00562-3]  GO BibTeX | EndNote: XML, Text | RIS

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ATM Deficiency Induces TGF-β-Mediated Stromal Programming in Pancreatic Cancer.
Cancer research nn, nn () [10.1158/0008-5472.CAN-26-0138]  GO BibTeX | EndNote: XML, Text | RIS

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Neurocognition after brain irradiation: dose-volume effects and regional radiosensitivity - a systematic review by the ESTRO CNS focus group.
Radiotherapy and oncology nn, nn () [10.1016/j.radonc.2026.111574]  GO BibTeX | EndNote: XML, Text | RIS

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Tumor microenvironment evaluation in lung cancer: Spatio-temporal dynamics and clinical implications.
Seminars in cancer biology nn, nn () [10.1016/j.semcancer.2026.04.003]  GO BibTeX | EndNote: XML, Text | RIS

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Capacitive heating devices for therapeutic hyperthermia: a review of essential physical characteristics and challenges.
Strahlentherapie und Onkologie nn, nn () [10.1007/s00066-026-02540-1]  GO BibTeX | EndNote: XML, Text | RIS

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Automated class-solution planning for biologically guided radiotherapy: a comparison with manual planning in head and neck cancer.
Physica medica 146, 105812 () [10.1016/j.ejmp.2026.105812]  GO BibTeX | EndNote: XML, Text | RIS

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Leukemic stem cell subtypes determine venetoclax resistance and therapeutic vulnerabilities in AML.
Cell stem cell nn, nn () [10.1016/j.stem.2026.04.012]  GO BibTeX | EndNote: XML, Text | RIS

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Neutrophil-Driven Trogocytosis in PDAC Liver Metastases Restrains Immunosuppressive Macrophage Polarization and Limits Metastatic Progression.
Gastroenterology nn, nn () [10.1053/j.gastro.2026.04.021]  GO BibTeX | EndNote: XML, Text | RIS

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The Relevance of Curative-Intent Metastasectomy in Colorectal Cancer Patients: Real-World Insights From a Certified Comprehensive Cancer Center in Germany.
International journal of cancer nn, nn () [10.1002/ijc.70540]  GO BibTeX | EndNote: XML, Text | RIS

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ASO Visual Abstract: Combined Preoperative Risk Score Including sCD40, Leukocytes, and BMI Predicts Pancreas-Specific Complications After Pancreatic Cancer Surgery
Annals of surgical oncology nn, nn () [10.1245/s10434-026-19708-9]  GO BibTeX | EndNote: XML, Text | RIS

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Deep molecular profiling of biliary tract cancer uncovers novel biological mechanisms and therapeutic opportunities.
ESMO open 11(5), 106082 () [10.1016/j.esmoop.2026.106082]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Response Assessment in Prostate Cancer using PSMA-PET. [Beurteilung des Therapieansprechens mit PSMA-PET]
Tumordiagnostik & Therapie 47(02), 101 - 104 () [10.1055/a-2786-2111]  GO BibTeX | EndNote: XML, Text | RIS

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IDH status shapes glioma oncotopy: voxel-wise mapping of 644 adult diffuse gliomas.
Neuroradiology nn, nn () [10.1007/s00234-026-03991-0]  GO BibTeX | EndNote: XML, Text | RIS

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Incorporating functional soft tissue deformations in AI model training for spatially accurate prostate cancer detection.
Magnetic resonance imaging nn, nn () [10.1016/j.mri.2026.110698]  GO BibTeX | EndNote: XML, Text | RIS

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Pancreatic cancer.
Nature reviews / Disease Primers 12(1), 23 () [10.1038/s41572-026-00699-6]  GO BibTeX | EndNote: XML, Text | RIS

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Darizmetinib (HRX215): A Promising 1st-in-Class Liver Regenerating Drug in Phase 1b/2a Clinical Development, Targeting the Stress Signaling Protein Kinase MKK4.
Journal of medicinal chemistry nn, nn () [10.1021/acs.jmedchem.6c00689]  GO BibTeX | EndNote: XML, Text | RIS

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Prognostic value of DICER and CA9 expression in patients with anal squamous cell carcinoma treated with definitive chemoradiotherapy.
European journal of cancer 241, 116776 () [10.1016/j.ejca.2026.116776]  GO BibTeX | EndNote: XML, Text | RIS

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Low-dose radiotherapy synergizes with PD-1 blockade to achieve durable survival in advanced NSCLC through antitumor neutrophil programming.
Signal transduction and targeted therapy 11(1), 170 () [10.1038/s41392-026-02712-6]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Author Correction: Multidimensional profiling of heterogeneity in supratentorial ependymomas.
Nature nn, nn () [10.1038/s41586-026-10602-8]  GO BibTeX | EndNote: XML, Text | RIS

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B7-H3 (CD276) as Target for T Cell-Based Bispecific Antibody Therapy of Penile Cancer.
ImmunoTargets & therapy 15, 1 - 19 () [10.2147/ITT.S577364]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Correction of the molecular phenotype of X-linked Dystonia-Parkinsonism reveals a non-canonical function of BRD4.
Nature Communications 17(1), 4062 () [10.1038/s41467-026-72319-6]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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How CAR T cells can be shielded from prostaglandin E2 signaling to enhance their therapeutic activity.
Molecular therapy. Oncology. 34(2), 201204 () [10.1016/j.omton.2026.201204]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Development of High-Affinity CHD1 Chromodomain Inhibitors.
Journal of medicinal chemistry nn, nn () [10.1021/acs.jmedchem.5c03690]  GO BibTeX | EndNote: XML, Text | RIS

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Case Report: Use of mirvetuximab soravtansine in a patient with platinum-resistant ovarian cancer and concomitant PARP-inhibitor-related myelodysplastic syndrome.
Frontiers in oncology 16, 1785547 () [10.3389/fonc.2026.1785547]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Molecular modulators of CDK4/6 inhibitor response in experimental glioma identified through genome-wide CRISPR-Cas9 screening.
Neuro-Oncology nn, nn () [10.1093/neuonc/noag093]  GO BibTeX | EndNote: XML, Text | RIS

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Multicentre validation of the PRECISE scoring system for prostate MRI during active surveillance.
European radiology nn, nn () [10.1007/s00330-026-12570-z]  GO BibTeX | EndNote: XML, Text | RIS

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ASO Author Reflections: sCD40 as a Preoperative Predictor in Pancreatic Cancer Surgery.
Annals of surgical oncology nn, nn () [10.1245/s10434-026-19716-9]  GO BibTeX | EndNote: XML, Text | RIS

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Emergency reversal of Rivaroxaban with Andexanet alfa in a child with hemorrhagic brain metastasis from Wilms tumor.
Child's nervous system 42(1), 195 () [10.1007/s00381-026-07286-w]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Impaired suppressive effect of FoxP3 regulatory T cells on B cells in multiple sclerosis.
Journal of neuroinflammation nn, nn () [10.1186/s12974-026-03776-5]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Paediatric Phase I/II Clinical Trial Assessments Under the New EU Clinical Trial Regulation: A Descriptive Analysis.
Pharmaceutical medicine nn, nn () [10.1007/s40290-026-00607-z]  GO BibTeX | EndNote: XML, Text | RIS

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Progress and challenges in the development of advanced pancreatic cancer organoids.
Journal of experimental & clinical cancer research nn, nn () [10.1186/s13046-026-03717-3]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Author Correction: Titration of RAS alters senescent state and influences tumour initiation.
Nature nn, nn () [10.1038/s41586-026-10601-9]  GO BibTeX | EndNote: XML, Text | RIS

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Discovery and Development of a Potent LIMK2 Isoform-Specific Degrader.
ACS chemical biology nn, nn () [10.1021/acschembio.6c00137]  GO BibTeX | EndNote: XML, Text | RIS

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Do AI-based contouring algorithms influence physicians in the online adaptive radiotherapy of patients with bladder cancer?
Technical innovations & patient support in radiation oncology 38, 100401 () [10.1016/j.tipsro.2026.100401]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Mouse TAPBPR shows functional similarity to human TAPBPR in shaping the MHC-I immunopeptidome.
Frontiers in immunology 17, 1756668 () [10.3389/fimmu.2026.1756668]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Checkpoint Breaches: Unexpected Effects of Anti-PD-1 Therapy on the Blood-Brain Barrier.
Cancer discovery 16(5), 831 - 833 () [10.1158/2159-8290.CD-26-0417]  GO BibTeX | EndNote: XML, Text | RIS

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The Equivalents Are Coming! Developing a Shared Nomenclature for Radiopharmaceutical Therapy of Neuroendocrine Tumors, Prostate Cancer, and Beyond.
Journal of nuclear medicine nn, nn () [10.2967/jnumed.126.272026]  GO BibTeX | EndNote: XML, Text | RIS

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Clinical trial endpoints for metastases-directed therapy in oligometastatic cancer: a review and Delphi consensus on behalf of the EORTC-ESTRO OligoCare consortium.
The lancet / Oncology 27(5), e238 - e247 () [10.1016/S1470-2045(26)00075-6]  GO BibTeX | EndNote: XML, Text | RIS

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Cell-free HPV DNA as a complementary biomarker to imaging in HPV-associated oropharyngeal squamous cell carcinoma: a narrative synthesis of key studies
Expert review of molecular diagnostics nn, nn () [10.1080/14737159.2026.2661735]  GO BibTeX | EndNote: XML, Text | RIS

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Combined Preoperative Risk Score Including sCD40, Leukocytes, and BMI Predicts Pancreas-Specific Complications After Pancreatic Cancer Surgery.
Annals of surgical oncology nn, nn () [10.1245/s10434-026-19628-8]  GO BibTeX | EndNote: XML, Text | RIS

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Spatially resolved ex vivo drug response profiling in SMARCB1-deficient sinonasal carcinoma.
EMBO molecular medicine nn, nn () [10.1038/s44321-026-00437-1]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Clinically actionable genomic and transcriptomic landscape of advanced neuroendocrine neoplasms.
Med nn, nn () [10.1016/j.medj.2026.101130]  GO BibTeX | EndNote: XML, Text | RIS

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Region- and sex-dependent single-cell transcriptomic signatures of neurons and glia in the prefrontal cortex and nucleus accumbens in a rat model of alcohol relapse.
Neuropharmacology nn, nn () [10.1016/j.neuropharm.2026.110995]  GO BibTeX | EndNote: XML, Text | RIS

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Artificial intelligence-based reclassification of gastric adenocarcinoma enables prognostic stratification via diffuse-type patch proportion.
International journal of medical informatics 215, 106455 () [10.1016/j.ijmedinf.2026.106455]  GO BibTeX | EndNote: XML, Text | RIS

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Heterogeneity in the management of patients with locally advanced pancreatic cancer: current surgeons' perspective and lessons for the future.
Updates in surgery nn, nn () [10.1007/s13304-026-02651-5]  GO BibTeX | EndNote: XML, Text | RIS

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Topical fullerene for preventing acute radiation dermatitis in head and neck cancer. [Topisches Fulleren zur Prävention der akuten Radiodermatitis bei Kopf-Hals-Tumoren.]
Strahlentherapie und Onkologie nn, nn () [10.1007/s00066-026-02543-y]  GO BibTeX | EndNote: XML, Text | RIS

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De-escalation of adjuvant radio(chemo)therapy for patients with HPV-positive head and neck squamous cell carcinoma: study protocol for a phase I trial to reduce late toxicity (DELPHI).
BMC cancer 26(1), 542 () [10.1186/s12885-026-16050-x]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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General health versus tumor stage: determinants of survival in Merkel cell carcinoma assessed by sentinel lymph node biopsy.
Journal of cancer research and clinical oncology 152(4), 100 () [10.1007/s00432-026-06485-x]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Error detection sensitivity and operational efficiency of phantom-based and phantom-less patient-specific quality assurance in proton therapy.
Zeitschrift für medizinische Physik nn, nn () [10.1016/j.zemedi.2026.04.002]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS