DKTK Publications

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The protein kinase IKK epsilon shapes the melanoma tumor microenvironment by modulating angiogenesis and the T-cell immunity.
Molecular medicine 32(1), 167 () [10.1186/s10020-026-01651-w]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Frameless VarioGuide biopsy for pediatric brainstem lesions in the molecular era: diagnostic performance and workflow characteristics in a comparative single-center series.
Child's nervous system 42(1), 379 () [10.1007/s00381-026-07484-6]  GO BibTeX | EndNote: XML, Text | RIS

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Machine learning models for adverse drug reaction prediction. A systematic review and three-level multilevel meta-analysis.
Frontiers in pharmacology 17, 1906920 () [10.3389/fphar.2026.1906920]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Pulmonary Artery Wall Abnormalities in an Asymptomatic Newborn Who Underwent Neonatal Absent Pulmonary Valve Syndrome Repair.
World journal for pediatric and congenital heart surgery nn, nn () [10.1177/21501351261480008]  GO BibTeX | EndNote: XML, Text | RIS

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Distinct Plasma Proteomic Signatures Distinguish MASLD From Non-Steatotic Individuals but Not From MetALD.
Liver international 46(10), e70873 () [10.1111/liv.70873]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Antibody-TLR3 agonist-conjugates program the tumor microenvironment and induce immune responses leading to tumor regression in experimental EGFRvIII-positive glioma.
Biomedicine & pharmacotherapy 204, 119947 () [10.1016/j.biopha.2026.119947]  GO BibTeX | EndNote: XML, Text | RIS

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Loss of PIMREG impairs double-strand break signaling and repair.
Biochimica et biophysica acta / Molecular basis of disease nn, nn () [10.1016/j.bbadis.2026.168486]  GO BibTeX | EndNote: XML, Text | RIS

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The MAMA-MIA Challenge: Advancing Generalizability and Fairness in Breast MRI Tumor Segmentation and Treatment Response Prediction
IEEE transactions on medical imaging nn, nn () [10.1109/TMI.2026.3733343]  GO BibTeX | EndNote: XML, Text | RIS

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All roads lead to ROAM: A look at the results of the ROAM/EORTC-1308 clinical trial.
Neuro-Oncology nn, nn () [10.1093/neuonc/noag234]  GO BibTeX | EndNote: XML, Text | RIS

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A transient MXD4-dependent proliferative pause enables survival of brain micrometastases.
Cancer cell nn, nn () [10.1016/j.ccell.2026.09.002]  GO BibTeX | EndNote: XML, Text | RIS

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Opposing functions of gut immunomodulatory metabolites on CAR-T therapy.
Cell nn, nn () [10.1016/j.cell.2026.09.004]  GO BibTeX | EndNote: XML, Text | RIS

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Proteomic Profiling of Post-COVID -19 Sequelae.
Molecular & cellular proteomics nn, nn () [DOI:10.1016/j.mcpro.2026.101670]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Targeting Kras signalling in a Trp53/KrasG12D mouse and organoid model inhibits Barrett esophagus to gastroesophageal adenocarcinoma progression
Scientific reports 16(1), 29356 () [10.1038/s41598-026-71355-y]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Spinal leptomeningeal disease in patients with solid tumors: A single-center study on clinical presentation, diagnosis, treatment, and outcomes
Brain and spine 6, 106660 () [10.1016/j.bas.2026.106660]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program.
Science 393(6818), eadw8520 () [10.1126/science.adw8520]  GO BibTeX | EndNote: XML, Text | RIS

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Protocol for ribosome-protected fragment isolation from rare leukemia cell populations.
STAR Protocols 7(4), 104861 () [10.1016/j.xpro.2026.104861]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET.
Advanced science nn, nn () [10.1002/advs.77830]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Diagnosis and treatment decision of an IDH-mutant glioma through CSF-based cfDNA sequencing.
Neuro-oncology advances 8(1), vdag240 () [10.1093/noajnl/vdag240]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Systemic Metabolic Changes in Plasma of Patients with Myelodysplastic Neoplasms and Chronic Myelomonocytic Leukemia.
Metabolites 16(9), 648 () [10.3390/metabo16090648]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Tutorial: interrogating biology using organoid technologies.
Nature protocols nn, nn () [10.1038/s41596-026-01447-6]  GO BibTeX | EndNote: XML, Text | RIS

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Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency.
Nature genetics nn, nn () [10.1038/s41588-026-02745-1]  GO BibTeX | EndNote: XML, Text | RIS

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Perioperative Outcomes of Patients With Pancreatic Neuroendocrine Neoplasms in the Context of Different Body Composition Phenotypes.
World journal of surgery nn, nn () [10.1002/wjs.70537]  GO BibTeX | EndNote: XML, Text | RIS

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Acute toxicity and patient-reported quality of life during daily online adaptive radiotherapy versus conventional IGRT for localized prostate cancer: a prospective parallel cohort study.
Strahlentherapie und Onkologie nn, nn () [10.1007/s00066-026-02596-z]  GO BibTeX | EndNote: XML, Text | RIS

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Functional proteomic and phosphoproteomic profiling of routine FFPE CNS tumor tissue complements genomic and epigenomic characterization.
Acta neuropathologica 152(1), 42 () [10.1007/s00401-026-03091-6]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Accelerating equitable cancer genomics and precision oncology in health care and research: a Lancet Oncology Commission.
The lancet / Oncology 27(10), e454-e507 () [10.1016/S1470-2045(26)00302-5]  GO BibTeX | EndNote: XML, Text | RIS

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Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.
The lancet nn, nn () [10.1016/S0140-6736(26)01804-0]  GO BibTeX | EndNote: XML, Text | RIS

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Correction: Secondary autoimmune and inflammatory diseases after allogeneic hematopoietic stem cell transplantation: a retrospective study from the EBMT transplant complications and autoimmune diseases working parties.
Bone marrow transplantation nn, nn () [10.1038/s41409-026-03047-0]  GO BibTeX | EndNote: XML, Text | RIS

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Interdisciplinary management and genetic evaluation of pediatric cancer predisposition syndromes: a retrospective cohort study.
European journal of human genetics nn, nn () [10.1038/s41431-026-02244-1]  GO BibTeX | EndNote: XML, Text | RIS

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MACC1 Hyperactivates Receptor Tyrosine Kinase Signaling Through Phosphorylation-Dependent Adaptor Activity in Colorectal Cancer Cells.
Biomolecules 16(9), 1267 () [10.3390/biom16091267]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Anatomy- and Time-Based Post-Processing with CT Perfusion-Derived Time-Vessel Maps to Reduce Incorrect Occlusion Detections in Late-Phase CT Angiography.
Diagnostics 16(18), 2972 () [10.3390/diagnostics16182972]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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The Value of Adjuvant Radiotherapy in the Treatment of Melanoma: A Multi-Center Analysis.
Cancers 18(18), 2901 () [10.3390/cancers18182901]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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TIGIT+ CD4+ T Cell Enrichment in Colorectal Liver Metastases Is Associated with Shorter Survival.
Cancers 18(18), 2977 () [10.3390/cancers18182977]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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The SPIZ study: rationale and protocol of a randomized controlled trial to optimize interdisciplinary care of patients following cellular therapy through a digitally supported, cross-regional and cross-sectoral care model.
Annals of hematology 105(10), 429 () [10.1007/s00277-026-07290-9]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Longitudinal transcriptomic profiling of paired early and metastatic EGFR-mutant lung adenocarcinomas reveals molecular programs associated with disease progression.
Lung cancer 221, 109628 () [10.1016/j.lungcan.2026.109628]  GO BibTeX | EndNote: XML, Text | RIS

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Proteogenomic Analysis of HDAC4 and HDAC5 in Uveal Melanoma.
Molecular medicine 32(1), 156 () [10.1186/s10020-026-01652-9]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Generation of an NG2 targeting bispecific antibody for the induction of T-cell immunity against melanoma.
Journal of translational medicine 24(1), 1204 () [10.1186/s12967-026-09000-5]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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A multicenter analysis of prognostic factors for patients undergoing re-irradiation for recurrent glioblastoma.
Neuro-oncology advances 8(1), vdag231 () [10.1093/noajnl/vdag231]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Allocation of TSPO-PET signals to cellular and extracellular compartments in dependence of blood-brain barrier disruption in experimental glioblastoma.
European journal of nuclear medicine and molecular imaging nn, nn () [10.1007/s00259-026-08187-5]  GO BibTeX | EndNote: XML, Text | RIS

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Author Correction: CLOCK/BMAL1 interactome uncovers homeodomain factors as tissue regulators.
Nature cell biology nn, nn () [10.1038/s41556-026-02092-7]  GO BibTeX | EndNote: XML, Text | RIS

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Integrating UHPLC-MS and MALDI-MSI for Spatial Nucleoside Profiling in FFPE Breast Cancer: A Multimodal Molecular Pathology Framework
Analytical chemistry nn, nn () [10.1021/acs.analchem.6c00978]  GO BibTeX | EndNote: XML, Text | RIS

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The Second Nitrogen Fits: Development of Diazine-Based Macrocyclic Chelators to Stably Bind Radionuclides Used in Targeted Alpha Therapy
Inorganic chemistry nn, nn () [10.1021/acs.inorgchem.6c01646]  GO BibTeX | EndNote: XML, Text | RIS

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Pitfalls in 2HG Detection With TE‐Optimized MRS at 3T
Journal of neuroimaging 36(5), e70146 () [10.1111/jon.70146]  GO BibTeX | EndNote: XML, Text | RIS

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Improving Reliability and Explainability of Medical Question Answering Through Atomic Fact-Checking in Retrieval-Augmented Large Language Models: Creation and Validation Study.
Journal of medical internet research 28, e92090 () [10.2196/92090]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Plain language summary of the RELATIVITY-098 study results: nivolumab plus relatlimab given after melanoma is removed by surgery.
Future oncology nn, nn () [10.1080/14796694.2026.2721180]  GO BibTeX | EndNote: XML, Text | RIS

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Key regulatory elements of the TGFβ-LRRC15 axis predict disease progression and immunotherapy resistance across cancer types.
Proceedings of the National Academy of Sciences of the United States of America 123(39), e2500524123 () [10.1073/pnas.2500524123]  GO BibTeX | EndNote: XML, Text | RIS

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Complete response of extensive cutaneous angiosarcoma of the scalp after PD1 immunotherapy combined with radiotherapy: A report of 2 cases
JAAD case reports 76, 144 - 146 () [10.1016/j.jdcr.2026.08.023]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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The Impact of the COVID-19 Pandemic on Childhood Cancer Survival: A Population-Based Assessment of Survival Patterns Between 2015 and 2023 in Germany.
Pediatric blood & cancer nn, nn () [10.1002/1545-5017.70706]  GO BibTeX | EndNote: XML, Text | RIS

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Concentrating cell-type-specific transcriptional signatures in bone marrow from interspecies comparisons.
Cell genomics nn, nn () [10.1016/j.xgen.2026.101365]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Trace-n-Seq combines retrograde fluorescent tracing with sorting and single-cell sequencing of innervating peripheral neurons.
Nature protocols nn, nn () [10.1038/s41596-026-01416-z]  GO BibTeX | EndNote: XML, Text | RIS

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Westernized diet related arachidonic acid metabolism expands DNA error-prone growth factor-dependent colonic quiescent stem cells in adolescent mice.
Cell death & disease 17(1), 798 () [10.1038/s41419-026-09240-9]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS