DKTK Publications (PubMed)

GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma.

Authors: Moore AR, Ran L, Guan Y, Sher JJ, Hitchman TD, Zhang JQ, Hwang C, Walzak EG, Shoushtari AN, Monette S, Murali R, Wiesner T, Griewank KG, Chi P, Chen Y

Published: Jun 2019 / Journal: Cell Rep
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Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4- d]pyrrolo[2,3- b]pyridine Scaffold.

Authors: Forster M, Chaikuad A, Dimitrov T, Döring E, Holstein J, Berger BT, Gehringer M, Ghoreschi K, Müller S, Knapp S, Laufer SA

Published: Jun 2019 / Journal: J Med Chem
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Computational analysis of receptor tyrosine kinase inhibitors and cancer metabolism: implications for treatment and discovery of potential therapeutic signatures.

Authors: Li J, Halfter K, Zhang M, Saad C, Xu K, Bauer B, Huang Y, Shi L, Mansmann UR

Published: Jun 2019 / Journal: BMC Cancer
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Checkpoint kinase 1 is essential for fetal and adult hematopoiesis.

Authors: Schuler F, Afreen S, Manzl C, Häcker G, Erlacher M, Villunger A

Published: Jun 2019 / Journal: EMBO Rep
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DNA repair and cancer in colon and rectum: novel players in genetic susceptibility.

Authors: Pardini B, Corrado A, Paolicchi E, Cugliari G, Berndt SI, Bezieau S, Bien SA, Brenner H, Caan BJ, Campbell PT, Casey G, Chan AT, Chang-Claude J, Cotterchio M, Gala M, Gallinger SJ, Haile RW, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hsu L, Huyghe J, Jenkins MA, Le Marchand L, Lin Y, Lindor NM, Nan H, Newcomb PA, Ogino S, Potter JD, Schoen RE, Slattery ML, White E, Vodickova L, Vymetalkova V, Vodicka P, Gemignani F, Peters U, Naccarati A, Landi S

Published: Jun 2019 / Journal: Int J Cancer
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In vitro sensitivity of malignant melanoma cells lines to photon and heavy ion radiation.

Authors: Aninditha KP, Weber KJ, Brons S, Debus J, Hauswald H

Published: Jun 2019 / Journal: Clin Transl Radiat Oncol
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Tamoxifen Pharmacogenetics and Metabolism: The Same Is Not the Same.

Authors: Brauch H, Schroth W, Mürdter T, Schwab M

Published: Jun 2019 / Journal: J Clin Oncol
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Linking bioenergetic function of mitochondriato tissue-specific molecular fingerprints.

Authors: Kappler L, Hoene M, Hu C, von Toerne C, Li J, Bleher D, Hoffmann C, Böhm A, Kollipara L, Zischka H, Königsrainer A, Häring HU, Peter A, Xu G, Sickmann A, Hauck SM, Weigert C, Lehmann R

Published: Jun 2019 / Journal: Am J Physiol Endocrinol Metab
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Efficacy of PD-1-based immunotherapy after radiologic progression on targeted therapy in stage IV melanoma.

Authors: Kreft S, Gesierich A, Eigentler T, Franklin C, Valpione S, Ugurel S, Utikal J, Haferkamp S, Blank C, Larkin J, Garbe C, Schadendorf D, Lorigan P, Schilling B

Published: Jun 2019 / Journal: Eur J Cancer
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[Validation of a 4-Item-Questionnaire on Familial and Hereditary Colorectal Cancer Risk in General Practice].

Authors: Koné I, Siebenhofer A, Hartig J, Plath J

Published: Jun 2019 / Journal: Gesundheitswesen
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Targeting tumor cell plasticity by combined inhibition of NOTCH and MAPK signaling in colon cancer.

Authors: Schmidt EM, Lamprecht S, Blaj C, Schaaf C, Krebs S, Blum H, Hermeking H, Jung A, Kirchner T, Horst D

Published: Jun 2019 / Journal: J Exp Med
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Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.

Authors: Huang M, Tailor J, Zhen Q, Gillmor AH, Miller ML, Weishaupt H, Chen J, Zheng T, Nash EK, McHenry LK, An Z, Ye F, Takashima Y, Clarke J, Ayetey H, Cavalli FMG, Luu B, Moriarity BS, Ilkhanizadeh S, Chavez L, Yu C, Kurian KM, Magnaldo T, Sevenet N, Koch P, Pollard SM, Dirks P, Snyder MP, Largaespada DA, Cho YJ, Phillips JJ, Swartling FJ, Morrissy AS, Kool M, Pfister SM, Taylor MD, Smith A, Weiss WA

Published: Jun 2019 / Journal: Cell Stem Cell
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BRCA Genes: The Role in Genome Stability, Cancer Stemness and Therapy Resistance.

Authors: Gorodetska I, Kozeretska I, Dubrovska A

Published: Jun 2019 / Journal: J Cancer
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Prognostic implication of molecular subtypes and response to neoadjuvant chemotherapy in 760 gastric carcinomas: role of Epstein Barr virus infection and high and low microsatellite instability.

Authors: Kohlruss M, Grosser B, Krenauer M, Slotta-Huspenina J, Jesinghaus M, Blank S, Novotny A, Reiche M, Schmidt T, Ismani L, Hapfelmeier A, Mathias D, Meyer P, Gaida MM, Bauer L, Ott K, Weichert W, Keller G

Published: Jun 2019 / Journal: J Pathol Clin Res
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The added value of health-related quality of life as a prognostic indicator of overall survival and progression-free survival in glioma patients: a meta-analysis based on individual patient data from randomised controlled trials.

Authors: Coomans M, Dirven L, K Aaronson N, Baumert BG, van den Bent M, Bottomley A, Brandes AA, Chinot O, Coens C, Gorlia T, Herrlinger U, Keime-Guibert F, Malmström A, Martinelli F, Stupp R, Talacchi A, Weller M, Wick W, Reijneveld JC, Taphoorn MJB, EORTC Quality of Life Group and the EORTC Brain Tumor Group

Published: Jun 2019 / Journal: Eur J Cancer
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