DKTK Publications

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Tumor-infiltrating CD8+Ki-67+ and CD8+LAG-3+ T cells are associated with improved patient survival in retroperitoneal dedifferentiated liposarcomas and leiomyosarcomas.
Experimental and molecular pathology 147, 105057 () [10.1016/j.yexmp.2026.105057]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Reverse engineering of BNIP3 identifies a mitochondrial protective peptide.
Nature Communications 17(1), 5359 () [10.1038/s41467-026-73993-2]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Integration and validation of complementary ex vivo assays for functional precision oncology.
npj precision oncology 10(1), 230 () [10.1038/s41698-026-01555-2]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Towards autonomous medical artificial intelligence agents.
Nature nn, nn () [10.1038/s41586-026-10675-5]  GO BibTeX | EndNote: XML, Text | RIS

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Clinical Implementation and Oncological Relevance of Molecular Profiling in Brain Metastases Patients-A Multicenter Retrospective Cohort Study.
International journal of cancer nn, nn () [10.1002/ijc.70611]  GO BibTeX | EndNote: XML, Text | RIS

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Teclistamab in relapsed/refractory light chain amyloidosis: A retrospective multicenter study by the German Society for Amyloid Diseases.
HemaSphere 10(6), e70389 () [10.1002/hem3.70389]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Fertility management and outcomes after CAR T-cell therapy: an international survey from the Cellular Therapy and Immunobiology working party of the European Society for Blood and Marrow Transplantation
EClinicalMedicine 96, 104014 () [10.1016/j.eclinm.2026.104014]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Challenging the control through a single-cell perspective on normal adjacent tissue in colorectal cancer
iScience 29(6), 115671 () [10.1016/j.isci.2026.115671]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Beyond attention heatmaps: How to get better explanations for multiple instance learning models in histopathology
Medical image analysis 113, 104148 () [10.1016/j.media.2026.104148]  GO BibTeX | EndNote: XML, Text | RIS

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Automated and personalized glioblastoma tumor organoid drug screening platform exposes sensitivity to proteasome and HDAC inhibitors.
npj precision oncology 10(1), 228 () [10.1038/s41698-026-01552-5]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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On the Scope of DCAF1-Recruiting PROTACs Degrading Protein Kinases.
Journal of medicinal chemistry nn, nn () [10.1021/acs.jmedchem.6c00383]  GO BibTeX | EndNote: XML, Text | RIS

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Stereotactic Radiosurgery for Brain Arteriovenous Malformations: A Radiosurgery Society Case-Based Guide
Practical Radiation Oncology nn, nn () [10.1016/j.prro.2026.04.001]  GO BibTeX | EndNote: XML, Text | RIS

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Non-invasive MRD monitoring and profiling of clonal evolution by ctDNA in patients with advanced cancers treated within molecular tumor boards.
Journal of clinical oncology 44(16_suppl), 3041 - 3041 () [10.1200/JCO.2026.44.16_suppl.3041]  GO BibTeX | EndNote: XML, Text | RIS

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A combined preoperative cardiorespiratory fitness and body composition phenotype is associated with major complications after pancreatoduodenectomy, independent of postoperative pancreatic fistula risk
European journal of surgical oncology 52(8), 111913 () [10.1016/j.ejso.2026.111913]  GO BibTeX | EndNote: XML, Text | RIS

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First-in-human EphA2-targeting PET imaging with the bicyclic radiotracer [68Ga]Ga-BCY18469 in pancreatic cancer patients: biodistribution, dosimetry and initial findings
European journal of nuclear medicine and molecular imaging nn, nn () [10.1007/s00259-026-07985-1]  GO BibTeX | EndNote: XML, Text | RIS

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p21-Activated Kinase (PAK) Group I-Targeting Inhibitors Promote the Dimeric Conformation in Live Cells.
ACS chemical biology nn, nn () [10.1021/acschembio.6c00410]  GO BibTeX | EndNote: XML, Text | RIS

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Local and global patterns support medical imaging as a biomarker of ageing.
Communications medicine 6(1), 335 () [10.1038/s43856-026-01722-3]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Extracorporeal Albumin Dialysis (OPAL) as Novel Therapeutic Bridging Option in Posthepatectomy Liver Failure.
Artificial organs nn, nn () [10.1111/aor.70187]  GO BibTeX | EndNote: XML, Text | RIS

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Transformer-based cardiac substructure segmentation from contrast and non-contrast computed tomography for radiotherapy planning.
Physics & Imaging in Radiation Oncology 39, 101011 () [10.1016/j.phro.2026.101011]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Diagnostic value of integrated 18F-fluorodeoxyglucose PET/MRI in initial staging and recurrence detection of Ewing sarcoma.
Nuclear medicine communications nn, nn () [10.1097/MNM.0000000000002196]  GO BibTeX | EndNote: XML, Text | RIS

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Inotuzumab ozogamicin in paediatric very high risk first B-cell acute lymphoblastic leukaemia relapse (ITCC-059): a multicentre, single-arm, phase 2 trial.
The lancet / Haematology nn, nn () [10.1016/S2352-3026(26)00104-3]  GO BibTeX | EndNote: XML, Text | RIS

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Corrigendum to 'Metabolic plasticity and optimal redox homeostasis are essential for efficient metastatic colonization' [Mol Metab 109 (2026) 102382/42155637].
Molecular metabolism nn, nn () [DOI:10.1016/j.molmet.2026.102401]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Oncogenic KRAS-driven type I interferon signalling primes pancreatic cancer for necroptosis.
Nature Communications 17(1), 5288 () [10.1038/s41467-026-73189-8]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Limitations in diagnostics and quantification of small lesions with low uptake in the clinical context of prostate 18F/68Ga-PSMA PET/MRI.
EJNMMI Physics nn, nn () [10.1186/s40658-026-00902-3]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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The SHH/GLI target Netrin-1 supports self-renewal in medulloblastoma tumor cells.
Cell communication and signaling nn, nn () [10.1186/s12964-026-02993-y]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Zapnometinib treatment and influenza A virus infection modulate the HLA class I ligandome in human lung adenocarcinoma cells.
Frontiers in immunology 17, 1790267 () [10.3389/fimmu.2026.1790267]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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PSA persistence in the PSMA PET era: reassessing a risk factor after radical prostatectomy.
Radiotherapy and oncology nn, nn () [10.1016/j.radonc.2026.111640]  GO BibTeX | EndNote: XML, Text | RIS

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Targetable alterations and personalized treatment in ameloblastoma: results from a prospective observational precision oncology study.
npj precision oncology 10(1), 217 () [10.1038/s41698-026-01527-6]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Spatial biomarker discovery via interpretable semantic learning in histopathology.
Cancer cell nn, nn () [10.1016/j.ccell.2026.05.014]  GO BibTeX | EndNote: XML, Text | RIS

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Towards robust foundation models for digital pathology.
Nature Communications 17(1), 5218 () [10.1038/s41467-026-73923-2]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Diagnostic Potential of Apparent Diffusion Coefficient-Based Lymph Node Classification in Breast Cancer Patients Undergoing [18F]FDG-PET/MRI.
Diagnostics 16(11), 1712 () [10.3390/diagnostics16111712]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Functional and behavioral outcomes in pediatric adrenal carcinoma under mitotane therapy: a caregiver-reported pilot study.
Endocrine oncology 6(1), e260010 () [10.1530/EO-26-0010]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Shear-wave ultrasound elastography for tissue-specific quantification of radiation-induced cervical fibrosis.
Physics & Imaging in Radiation Oncology 39, 101005 () [10.1016/j.phro.2026.101005]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Postoperative fractionated stereotactic radiotherapy for completely resected brain metastases with 25 Gy in five fractions: A single-center retrospective study.
Clinical and translational radiation oncology 59, 101198 () [10.1016/j.ctro.2026.101198]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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[68Ga]Ga-NECT-224 PET/CT Shows Increasing Nectin-4 Expression in Progressive Urothelial Carcinoma Under ADC-Therapy With Enfortumab-Vedotin.
Clinical nuclear medicine nn, nn () [10.1097/RLU.0000000000006528]  GO BibTeX | EndNote: XML, Text | RIS

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Radiation therapy in adolescents and young adults (AYA): contemporary evidence on utilization, outcomes, late toxicities, and second malignant neoplasms - A comprehensive systematic review and synthesis.
Radiotherapy and oncology nn, nn () [10.1016/j.radonc.2026.111638]  GO BibTeX | EndNote: XML, Text | RIS

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A Modified Balanced Steady State Free Precession Sequence for Overhauser Magnetic Resonance Imaging.
Magnetic resonance in medicine nn, nn () [10.1002/mrm.70453]  GO BibTeX | EndNote: XML, Text | RIS

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Correction of Ineffective Erythropoiesis and Normalization of Iron Homeostasis After Exagamglogene Autotemcel in Transfusion-Dependent β-Thalassemia.
American journal of hematology nn, nn () [10.1002/ajh.70382]  GO BibTeX | EndNote: XML, Text | RIS

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l-2-Hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression
The journal of clinical investigation 136(9), e197010 () [10.1172/JCI197010]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Moving Tumor-Agnostic Therapy to the Big Stage: Translational and Molecular Oncology Highlights from the ESMO Congress 2025
Oncology research and treatment nn, nn () [10.1159/000551042]  GO BibTeX | EndNote: XML, Text | RIS

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Blood-based DNA methylation marker model for short-term and long-term lung cancer risk prediction.
BMC medicine 24(1), 344 () [10.1186/s12916-026-04973-y]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Machine Learning-Guided Survival Prediction and Treatment Sequencing in Advanced Soft Tissue Sarcoma Beyond Second-Line Therapy: A Retrospective Cohort Study.
Oncology and Therapy nn, nn () [10.1007/s40487-026-00446-7]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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APOBEC2 deficiency disrupts hematopoietic lineage commitment, resulting in emergence of dual identity lymphocytes in mice and humans.
Proceedings of the National Academy of Sciences of the United States of America 123(23), e2531122123 () [10.1073/pnas.2531122123]  GO BibTeX | EndNote: XML, Text | RIS

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First-In-Human Evaluation of [18F]Fluproxadine for Norepinephrine Transporter PET: Biodistribution, Dosimetry, and Safety.
Clinical nuclear medicine 51(7), 555 - 564 () [10.1097/RLU.0000000000006504]  GO pmc   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Contrast enhanced CT and MRI interchangeably reflect tumor characteristics in murine pancreatic cancer.
Scientific reports 16(1), 17516 () [10.1038/s41598-026-56008-4]  GO DBCoverage   Download fulltextFulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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Human immunosuppressive neutrophils: recent answers to old and new questions.
The EMBO journal nn, nn () [10.1038/s44318-026-00829-6]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Discovery of ferroptosis-inducing R4VP compounds for targeting aggressive cancers.
Oncogene nn, nn () [10.1038/s41388-026-03829-2]  GO BibTeX | EndNote: XML, Text | RIS

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CircRNAs derived from the tyrosine phosphatase PTPN22 impact chemosensitivity in ALK-positive T-cell lymphomas.
Scientific reports nn, nn () [10.1038/s41598-026-54978-z]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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GATA6-CRT axis promotes stress-associated autophagy, EMT, and stemness-associated traits in pancreatic cancer.
Cell death & disease nn, nn () [10.1038/s41419-026-08914-8]  GO DBCoverage BibTeX | EndNote: XML, Text | RIS

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Pathogenesis of diffuse large B cell lymphoma proteogenotypes.
Cancer cell nn, nn () [10.1016/j.ccell.2026.05.008]  GO BibTeX | EndNote: XML, Text | RIS