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Hoffmeister-Wittmann, P. ; Hoegen-Saßmannshausen, P. ; Wicklein, L. ; Weykamp, F. ; Seidensaal, K. ; Springfeld, C. ; Dill, M. ; Longerich, T. ; Schirmacher, P. ; Mehrabi, A. ; Mathy, R. M. ; Köhler, B. C. ; Debus, J. ; Herfarth, K. ; Liermann, J.
Stereotactic body radiotherapy with carbon ions as local ablative treatment in patients with primary liver cancer.
Radiation oncology 20(1), 23 (2025) [10.1186/s13014-025-02594-y]2025
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Bertrand, L. ; Nelde, A. ; Ramirez, B. C. ; Hatin, I. ; Arbes, H. ; François, P. ; Demais, S. ; Labaronne, E. ; Decimo, D. ; Guiguettaz, L. ; Grégoire, S. ; Bet, A. ; Beauclair, G. ; Gross, A. ; Ziegler, M. C. ; Pereira, M. ; Jeger-Madiot, R. ; Verdier, Y. ; Vinh, J. ; Cardinaud, S. ; Graff-Dubois, S. ; Esclatine, A. ; Gouttefangeas, C. ; Altfeld, M. ; Hocqueloux, L. ; Samri, A. ; Autran, B. ; Lambotte, O. ; Rammensee, H.-G. ; Ricci, E. P. ; Walz, J. ; Namy, O. ; Moris, A.
Unveiling conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling.
Nature Communications 16(1), 1707 (2025) [10.1038/s41467-025-56773-2]2025
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Cai, L. ; Hammond, N. G. ; Tasdogan, A. ; Alsamraae, M. ; Yang, C. ; Cameron, R. B. ; Quan, P. ; Solmonson, A. ; Gu, W. ; Pachnis, P. ; Kaur, M. ; Chang, B. K. ; Zhou, Q. ; Hensley, C. T. ; Do, Q. N. ; Martins Nascentes Melo, L. ; Ubellacker, J. M. ; Kaushik, A. ; Clare, M. G. ; Alcazar, I. N. ; Kurylowicz, K. ; Marcuccilli, J. D. ; Allies, G. ; Kutritz, A. ; Klode, J. ; Ramesh, V. ; Rogers, T. J. ; Rao, A. D. ; Crentsil, H. E. ; Li, H. ; Brister, F. ; McDaniel, P. ; Xu, X. ; Evers, B. M. ; Zacharias, L. G. ; Sudderth, J. ; Xu, J. ; Mathews, T. P. ; Oliver, D. ; Minna, J. D. ; Waters, J. ; Morrison, S. J. ; Kernstine, K. H. ; Faubert, B. ; DeBerardinis, R. J.
High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non-Small Cell Lung Cancer in Patients.
Cancer discovery nn, nn (2025) [10.1158/2159-8290.CD-23-1319]2025
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Stock, A. ; Krumma, J. ; Fleischhack, G. ; Tippelt, S. ; Rink, L. ; Pietsch, T. ; Mynarek, M. ; Obrecht-Sturm, D. ; Rutkowski, S. ; Pfister, S. ; Sturm, D. ; Pajtler, K. ; Schüller, U. ; Timmermann, B. ; Kortmann, R.-D. ; Bison, B. ; Pham, M. ; Warmuth-Metz, M.
Recurrence patterns in pediatric intracranial ependymal neoplasm: a systematic imaging work-up.
Neuroradiology nn, nn (2025) [10.1007/s00234-025-03553-w]2025
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Thiel, V. (First author) ; Renders, S. (First author) ; Panten, J. (First author) ; Dross, N. ; Bauer, K. ; Azorin, D. ; Henriques, V. ; Vogel, V. ; Klein, C. ; Leppä, A.-M. ; Barriuso Ortega, I. ; Schwickert, J. ; Ourailidis, I. ; Mochayedi, J. ; Mallm, J.-P. ; Müller-Tidow, C. ; Monyer, H. ; Neoptolemos, J. ; Hackert, T. ; Stegle, O. ; Odom, D. ; Offringa, R. ; Stenzinger, A. ; Winkler, F. ; Sprick, M. ; Trumpp, A. (Last author)
Characterization of single neurons reprogrammed by pancreatic cancer.
Nature nn, nn (2025) [10.1038/s41586-025-08735-3]2025
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Pauck, D. ; Picard, D. J. ; Maue, M. ; Taban, K. ; Marquardt, V. ; Blümel, L. ; Bartl, J. ; Qin, N. ; Kubon, N. ; Schöndorf, D. ; Meyer, F.-D. ; Theruvath, J. ; Mitra, S. ; Hasselblatt, M. ; Frühwald, M. C. ; Reifenberger, G. ; Remke, M.
An in vitro pharmacogenomic approach reveals subtype-specific therapeutic vulnerabilities in atypical teratoid/rhabdoid tumors (AT/RT).
Pharmacological research nn, nn (2025) [10.1016/j.phrs.2025.107660]2025
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Wulff, J. ; Koska, B. ; Giese, M. ; Bäumer, C. ; Richter, R. ; Foerster, A. ; Bechrakis, N. E. ; Timmermann, B.
Evaluation of OPTOS wide-field fundus image projections for radiotherapy planning of uveal melanoma.
Journal of applied clinical medical physics nn, nn (2025) [10.1002/acm2.70009]2025
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Moser, L. M. ; Heim, C. ; Koschade, S. E. ; Wendel, P. ; Bozkurt, S. ; Harenkamp, S. ; Kreyenberg, H. ; Merker, M. ; Münch, C. ; Gradhand, E. ; Vogler, M. ; Ullrich, E. ; Bönig, H. ; Klusmann, J.-H. ; Bader, P. ; Wels, W. S. ; Rettinger, E.
CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma.
Frontiers in immunology 16, 1485817 (2025) [10.3389/fimmu.2025.1485817]2025
Fulltext by Pubmed Central
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Chiaffarelli, R. ; Cruz, P. F. ; Cotton, J. ; Kelm, T. ; Lee, S. ; Ghaderian, M. ; Zimmermann, M. ; Geraldes, C. F. G. C. ; Jurek, P. ; Martins, A.
Metabolic PCTA-Based Shift Reagents for the Detection of Extracellular Lactate Using CEST MRI
JACS Au nn, nn (2025) [10.1021/jacsau.4c01020]2025
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Launspach, M. ; Mindermann, A. ; Schulz, J. ; Alasfar, L. ; Cyrull, S. ; Zirngibl, F. ; Oevermann, L. ; Künkele, A. ; Deubzer, H. E. ; von Bernuth, H. ; Pruß, A. ; Lang, P. ; Bufler, P. ; Eggert, A. ; von Stackelberg, A. ; Schulte, J.
High Incidence and Impact of Suspected Exocrine Pancreatic Insufficiency in Patients Post-Hematopoietic Stem Cell Transplantation: A Single-Center Prospective Observational Study.
United european gastroenterology journal nn, nn (2025) [10.1002/ueg2.12769]2025
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Müller, M. ; Zodel, K. ; Abhari, B. A. ; Cuomo, F. ; Nizamuddin, S. ; Metzger, P. ; Börries, M. ; Timmers, H. T. M. ; Frew, I. J.
KDM5C and KDM5D mutations have different consequences in clear cell renal cell carcinoma cells.
Communications biology 8(1), 244 (2025) [10.1038/s42003-025-07695-8]2025
Fulltext by Pubmed Central
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Bröckelmann, P. J. ; von Tresckow, B.
Reply to the Letter to the Editor 'Comments on the study of correlation between progression-free and overall survival in patients with Hodgkin lymphoma' by Zeng et al.
Annals of oncology nn, nn (2025) [10.1016/j.annonc.2025.01.013]2025
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Pretzsch, E. ; Peschel, C. A. ; Rokavec, M. ; Torlot, L. ; Li, P. ; Hermeking, H. ; Werner, J. ; Klauschen, F. ; Neumann, J. ; Jung, A. ; Kumbrink, J.
Five-gene expression signature associated with acquired FOLFIRI resistance and survival in metastatic colorectal cancer.
Laboratory investigation nn, nn (2025) [10.1016/j.labinv.2025.104107]2025
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Langenberg, K. P. S. ; van Hooff, S. R. ; Koopmans, B. ; Strijker, J. G. M. ; Kholosy, W. M. ; Ober, K. ; Zwijnenburg, D. A. ; van der Hoek, J. J. F. ; Keller, K. M. ; Vernooij, L. ; Schild, L. G. ; Looze, E. J. ; Ebus, M. E. ; Essing, A. H. W. ; Vree, P. d. ; Tas, M. L. ; Matser, Y. A. H. ; Wienke, J. ; Volckmann, R. ; Tops, B. B. J. ; Kester, L. A. ; Badloe, S. ; Hehir-Kwa, J. Y. ; Kemmeren, P. ; Goemans, B. F. ; Zwaan, C. M. ; Oehme, I. ; Jäger, N. ; Witt, O. ; van Eijkelenburg, N. K. A. ; Dierselhuis, M. P. ; Tytgat, G. A. M. ; Wijnen, M. H. W. ; van Noesel, M. M. ; de Krijger, R. R. ; Eising, S. ; Koster, J. ; Dolman, E. M. ; Molenaar, J. J.
Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine.
European journal of cancer 218, 115275 (2025) [10.1016/j.ejca.2025.115275]2025
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Cibir, Z. ; Beer, A. ; Kraus, A. ; Pillibeit, A. ; Bludau, D. ; Abdulla, H. ; Neuendorff, N. R. ; Sonneck, J. ; Kowitz, L. ; Riese, S. ; Tuz, A. A. ; Chen, J. ; Cherneha, M. ; Beelen, D. W. ; Reinhardt, H. C. ; Gunzer, M. ; Turki, A. T.
Risk beyond neutropenia: insights into neutrophil migration from newly diagnosed AML until late after allogeneic stem cell transplantation.
Journal of leukocyte biology 117(2), qiae250 (2025) [10.1093/jleuko/qiae250]2025
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Walter, C. B. ; Hartkopf, A. D. ; Hein, A. ; Fasching, P. A. ; Kolberg, H.-C. ; Hadji, P. ; Tesch, H. ; Häberle, L. ; Ettl, J. ; Lüftner, D. ; Wallwiener, M. ; Müller, V. ; Beckmann, M. W. ; Michel, L. L. ; Belleville, E. ; Huebner, H. ; Uhrig, S. ; Goossens, C. ; Wimberger, P. ; Hielscher, C. ; Meyer, J. ; Mundhenke, C. ; Kurbacher, C. ; Wuerstlein, R. ; Untch, M. ; Janni, W. ; Taran, F.-A. ; Lux, M. P. ; Wallwiener, D. ; Brucker, S. Y. ; Schneeweiss, A. ; Fehm, T. N. ; Fremd, C.
Characteristics and prognosis of patients with primary metastatic disease vs. recurrent HER2-negative, hormone receptor-positive advanced breast cancer.
The breast 80, 104412 (2025) [10.1016/j.breast.2025.104412]2025
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Wach, J. ; Basaran, A. E. ; Vychopen, M. ; Tihan, T. ; Wostrack, M. ; Butenschoen, V. M. ; Meyer, B. ; Siller, S. ; Schmidt, N. O. ; Onken, J. ; Vajkoczy, P. ; Santos, A. N. ; Rauschenbach, L. ; Dammann, P. ; Sure, U. ; Klingler, J.-H. ; Doria-Medina, R. ; Beck, J. ; Blaß, B.-I. ; Gizaw, C. J. ; Hohenhaus, R. ; Krieg, S. ; Alhalabi, O. T. ; Klein, L. ; Thomé, C. ; Kögl, N. ; Kunert, P. ; Czernicki, T. ; Pantel, T. ; Middelkamp, M. ; Eicker, S. O. ; Kattaa, A. H. ; Park, D. J. ; Chang, S. D. ; Kilinc, F. ; Czabanka, M. ; Güresir, E.
Local tumor control and neurological outcomes after surgery for spinal hemangioblastomas in sporadic and Von-Hippel-Lindau Disease: A multicenter study.
Neuro-Oncology nn, nn (2025) [10.1093/neuonc/noaf041]2025
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Klüter, S. ; Milewski, K. ; Johnen, W. ; Brons, S. ; Naumann, J. ; Dorsch, S. ; Beyer, C. ; Paul, K. ; Dietrich, K. ; Platt, T. ; Debus, J. ; Bauer, J.
First dosimetric evaluation of clinical raster-scanned proton, helium and carbon ion treatment plan delivery during simultaneous real-time magnetic resonance imaging
Physics & Imaging in Radiation Oncology 33, 100722 (2025) [10.1016/j.phro.2025.100722]2025
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Klein, L. ; Herget, G. ; Schmal, H. ; Grosu, A.-L. ; Sprave, T. ; Stoian, R.
Radiotherapy of osseus metastases.[Strahlentherapie ossärer Metastasen.]
Best Practice Onkologie nn, nn (2025) [10.1007/s11654-024-00626-9]2025
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Cordts, I. ; Fuetterer, C. ; Wachinger, A. ; von Heynitz, R. ; Kessler, T. ; Freigang, M. ; Quinten, A. L. ; Bjelica, B. ; Brakemeier, S. ; Hobbiebrunken, E. ; Hagenacker, T. ; Petri, S. ; Koch, J. C. ; Hahn, A. ; Lingor, P. ; Deschauer, M. ; Günther, R. ; Weiler, M. ; Haller, B. ; Feneberg, E.
Long-Term Dynamics of CSF and Serum Neurofilament Light Chain in Adult Patients With 5q Spinal Muscular Atrophy Treated With Nusinersen.
Neurology 104(5), e213371 (2025) [10.1212/WNL.0000000000213371]2025
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Shah, V. ; Giotopoulos, G. ; Osaki, H. ; Meyerhöfer, M. ; Meduri, E. ; Gallego-Crespo, A. ; Behrendt, M. A. ; Saura-Pañella, M. ; Tarkar, A. ; Schubert, B. ; Yun, H. ; Horton, S. J. ; Agrawal-Singh, S. ; Haehnel, P. S. ; Basheer, F. ; Lugo, D. ; Eleftheriadou, I. ; Barbash, O. ; Dhar, A. ; Kühn, M. W. M. ; Guezguez, B. ; Theobald, M. ; Kindler, T. ; Gallipoli, P. ; Yeh, P. ; Dawson, M. A. ; Prinjha, R. K. ; Huntly, B. J. P. ; Sasca, D.
Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation.
Blood 145(7), 748 - 764 (2025) [10.1182/blood.2022019306]2025
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Lalos, F. ; Flühs, D. ; Guberina, M. ; Bornfeld, N. ; Stuschke, M. ; Sauerwein, W. ; Bechrakis, N. E.
Treatment-Related Complications and Functional Results after Ruthenium-106 Brachytherapy in Small to Medium Size Uveal Melanomas (Part 2). [Behandlungsbedingte Komplikationen und funktionelle Ergebnisse nach Ruthenium-106-Brachytherapie bei kleinen bis mittelgroßen Aderhautmelanomen (Teil 2)].
Klinische Monatsblätter für Augenheilkunde 242(2), 116 - 126 (2025) [10.1055/a-2275-5575]2025
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Lalos, F. ; Flühs, D. ; Guberina, M. ; Bornfeld, N. ; Stuschke, M. ; Sauerwein, W. ; Bechrakis, N. E.
Tumor- and Radiation-Related Complications after Ruthenium-106 Brachytherapy in Small to Medium Uveal Melanomas (Part 1). [Tumor- und strahlenbedingte Komplikationen nach Ruthenium-106-Brachytherapie bei kleinen bis mittelgroßen Aderhautmelanomen (Teil 1)].
Klinische Monatsblätter für Augenheilkunde 242(2), 105 - 115 (2025) [10.1055/a-2268-0985]2025
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Anker, M. S. ; Bullinger, L. ; Keller, U. ; Khan, M. S.
Growth Differentiation Factor-15: A Promising Biomarker and Target in Cancer Patients
JACC: CardioOncology 7(2), 153-156 (2025) [10.1016/j.jaccao.2025.01.001]2025
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Scheffler, P. ; Straehle, J. ; El Rahal, A. ; Erny, D. ; Mizaikoff, B. ; Vasilikos, I. ; Prinz, M. ; Coenen, V. A. ; Kühn, J. ; Scherer, F. ; Heiland, D. H. ; Schnell, O. ; Roelz, R. ; Beck, J. ; Reinacher, P. C. ; Neidert, N.
Intraoperative classification of CNS lymphoma and glioblastoma by AI-based analysis of Stimulated Raman Histology (SRH)
Brain and spine 5, 104187 (2025) [10.1016/j.bas.2025.104187]2025
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Heinrich, K. ; von Lilienfeld-Toal, M.
The Critical Role of Sex and Gender in Medicine
Oncology research and treatment 48(1-2), 1 - 3 (2025) [10.1159/000542508]2025
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Adabi, E. ; Charitidis, F. T. ; Thalheimer, F. B. ; Guaza-Lasheras, M. ; Clarke, C. ; Buchholz, C. J.
Enhanced conversion of T cells into CAR T cells by modulation of the MAPK/ERK pathway.
Cell reports / Medicine nn, nn (2025) [10.1016/j.xcrm.2025.101970]2025
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Peng, T. ; Ma, X. (First author) ; Hua, W. ; Wang, C. ; Chu, Y. ; Sun, M. ; Fermi, V. ; Hamelmann, S. ; Lindner, K. ; Shao, C. ; Zaman, J. ; Tian, W. ; Zhuo, Y. ; Harim, Y. ; Stöffler, N. ; Hammann, L. ; Xiao, Q. ; Jin, X. ; Warta, R. ; Lotsch, C. ; Zhuang, X. ; Feng, Y. ; Fu, M. ; Zhang, X. ; Zhang, J. ; Xu, H. ; Qiu, F. ; Xie, L. ; Zhang, Y. ; Zhu, W. ; Du, Z. ; Salgueiro, L. ; Schneider, M. ; Eichhorn, F. ; Lefevre, A. ; Pusch, S. ; Grinevich, V. ; Ratliff, M. ; Loges, S. ; Bunse, L. ; Sahm, F. ; Xiang, Y. ; Unterberg, A. ; von Deimling, A. ; Platten, M. ; Herold-Mende, C. ; Wu, Y. ; Liu, H. ; Mao, Y.
Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy.
Cell stem cell nn, nn (2025) [10.1016/j.stem.2025.01.002]2025
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Pal, J. ; Riester, M. ; Ganner, A. ; Ghosh, A. ; Dhamija, S. ; Mookherjee, D. ; Voss, C. ; Frew, I. J. ; Kotsis, F. ; Neumann-Haefelin, E. ; Spang, A. ; Diederichs, S.
Nonstop mutations cause loss of renal tumor suppressor proteins VHL and BAP1 and affect multiple stages of protein translation.
Science advances 11(7), eadr6375 (2025) [10.1126/sciadv.adr6375]2025
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Jabbarli, L. ; Fiorentzis, M. ; Rating, P. ; Schmidt, B. ; Biewald, E. ; Guberina, N. ; Flühs, D. ; Bornfeld, N. ; Sauerwein, W. ; Stuschke, M. ; Bechrakis, N. E. ; Guberina, M.
Functional outcome after Brachytherapy with bi-nuclide (Ru-106/Iodine-125) plaques in large uveal melanomas.
Radiation oncology 20(1), 22 (2025) [10.1186/s13014-024-02576-6]2025
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Hartmann, A. ; Grabitz, S. D. ; Wild, P. S. ; Lackner, K. J. ; Münzel, T. ; Kerahrodi, J. G. ; Singer, S. ; Geschke, K. ; Schattenberg, J. M. ; Konstantinides, S. ; Pfeiffer, N. ; Schuster, A. K.
Gender-specific changes in vision-related quality of life over time - results from the population-based Gutenberg Health Study.
Graefe's archive for clinical and experimental ophthalmology nn, nn (2025) [10.1007/s00417-025-06741-9]2025
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Wasilewski, D. ; Eitner, C. ; Ates, R. ; Murad, S. ; Shaked, Z. ; Steinle, J. A. ; Wetzel-Yalelis, A. ; Sargut, T. A. ; Rösler, J. ; Samman, M. A. ; Truckenmüller, P. ; Mertens, R. ; Kroneberg, D. ; Kowski, A. ; Radbruch, H. ; Capper, D. ; Ehret, F. ; Roohani, S. ; Frost, N. ; Nawabi, J. ; Onken, J. ; Schlaak, M. ; Blohmer, J.-U. ; Pelzer, U. ; Keller, U. ; Sehouli, J. ; Vajkoczy, P. ; Keilholz, U. ; Misch, M.
Clinical characteristics and outcomes in leptomeningeal disease with or without brain metastasis: insights from an explorative data analysis of the Charité LMD registry.
Journal of neuro-oncology nn, nn (2025) [10.1007/s11060-025-04937-x]2025
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Miletić, N. ; Weckesser, J. ; Mosler, T. ; Rathore, R. ; Hoffmann, M. E. ; Gehrtz, P. ; Schlesiger, S. ; Hartung, I. V. ; Berner, N. ; Wilhelm, S. ; Müller, J. ; Adhikari, B. ; Němec, V. ; Sivashanmugam, S. A. ; Elson, L. ; Holzmann, H. ; Schwalm, M. P. ; Hoffmann, L. ; Abdul Azeez, K. R. ; Müller, S. ; Kuster, B. ; Wolf, E. ; Đikić, I. ; Knapp, S.
Workflow for E3 Ligase Ligand Validation for PROTAC Development.
ACS chemical biology nn, nn (2025) [10.1021/acschembio.4c00812]2025
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Braun, L. M. ; Giesler, S. ; Andrieux, G. ; et al
Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity
Cancer cell 43(2), 269 - 291.e19 (2025) [10.1016/j.ccell.2025.01.004]2025
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Wiala, A. ; Elhage, K. G. ; Leung, A. ; Young, A. T. ; Gregory, M. ; Adrianto, I. ; Zhou, L. ; Mi, Q.-S. ; Kumar, S. ; Orcales, F. ; Yeroushalmi, S. ; Haran, K. ; Liu, J. ; Naik, H. B. ; Liao, W. ; Posch, C.
Patients with PSOriasis and Suppurative Hidradenitis (PSO-SH) share genetic risk factors and are at risk of increased morbidity.
Journal of the American Academy of Dermatology nn, nn (2025) [10.1016/j.jaad.2025.02.015]2025
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Hsu, M.-T. ; Willimsky, G. ; Hansmann, L. A. ; Blankenstein, T.
T cell receptors specific for an imatinib-induced mutation in BCR-ABL for adoptive T cell therapy.
Frontiers in immunology 16, 1518691 (2025) [10.3389/fimmu.2025.1518691]2025
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Frick, C. (First author) ; Seum, T. ; Bhardwaj, M. ; Holland-Letz, T. ; Schöttker, B. ; Brenner, H. (Last author)
Head-to-head comparisons of risk discrimination by questionnaire-based lung cancer risk prediction models: a systematic review and meta-analysis
EClinicalMedicine 80, 103075 (2025) [10.1016/j.eclinm.2025.103075]2025
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Rosnev, S. ; Peuker, C. A. ; Piwonski, I. ; Ihlow, J. ; Leyvraz, S. ; Klingberg, J. ; Horst, D. ; Joosten, M. ; Möbs, M. ; Joussen, A. M. ; de Bucourt, M. ; Keilholz, U. ; Keller, U. ; Ochsenreither, S. ; Rittig, S. M.
Characterizing uveal melanoma patients with peritoneal metastases: A retrospective single-center analysis.
European journal of cancer 218, 115280 (2025) [10.1016/j.ejca.2025.115280]2025
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Crespo, E. ; Loureiro, L. R. ; Stammberger, A. ; Hoffmann, L. ; Berndt, N. ; Hoffmann, A. ; Dagostino, C. ; Soto, K. E. G. ; Rupp, L. ; Arndt, C. ; Schneider, M. ; Ball, C. ; Bachmann, M. ; Schmitz, M. ; Feldmann, A.
RevCAR-mediated T-cell response against PD-L1-expressing cells turns suppression into activation.
npj precision oncology 9(1), 42 (2025) [10.1038/s41698-025-00828-6]2025
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Lüchtenborg, A.-M. ; Vaupel, P. ; Thomsen, H. ; Piazena, H.
Clarifications and comments on 'infrared radiation for cancer hyperthermia: the light to brighten up oncology'.
Expert review of anticancer therapy nn, nn (2025) [10.1080/14737140.2025.2465890]2025
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Xu, Y. ; Peng, X. L. ; East, M. P. ; McCabe, I. C. ; Stroman, G. C. ; Jenner, M. R. ; Chan, P. S. ; Morrison, A. B. ; Shen, E. C. ; Hererra, S. G. ; Joisa, C. U. ; Rashid, N. U. ; Iuga, A. C. ; Gomez, S. M. ; Miller-Phillips, L. ; Boeck, S. ; Heinemann, V. ; Haas, M. ; Ormanns, S. ; Johnson, G. L. ; Yeh, J. J.
Tumor-Intrinsic Kinome Landscape of Pancreatic Cancer Reveals New Therapeutic Approaches.
Cancer discovery 15(2), 346 - 362 (2025) [10.1158/2159-8290.CD-23-1480]2025
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Declercq, A. ; Devreese, R. ; Scheid, J. ; Jachmann, C. ; Van Den Bossche, T. ; Preikschat, A. ; Gómez-Zepeda, D. ; Rijal, J. B. ; Hirschler, A. ; Krieger, J. R. ; Srikumar, T. ; Rosenberger, G. ; Martelli, C. ; Trede, D. ; Carapito, C. ; Tenzer, S. ; Walz, J. S. ; Degroeve, S. ; Bouwmeester, R. ; Martens, L. ; Gabriels, R.
TIMS2Rescore: A Data Dependent Acquisition-Parallel Accumulation and Serial Fragmentation-Optimized Data-Driven Rescoring Pipeline Based on MS2Rescore.
Journal of proteome research nn, nn (2025) [10.1021/acs.jproteome.4c00609]2025
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Deutscher, R. C. E. ; Meyners, C. ; Repity, M. L. ; Sugiarto, W. O. ; Kolos, J. M. ; Maciel, E. V. S. ; Heymann, T. ; Geiger, T. M. ; Knapp, S. ; Lermyte, F. ; Hausch, F.
Discovery of fully synthetic FKBP12-mTOR molecular glues.
Chemical science nn, nn (2025) [10.1039/D4SC06917J]2025
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Fuchs, F. ; Rogowski, P. ; Rottler, M. ; Shouman, M. A. ; Heinrich, K. ; Kühn, F. ; Belka, C. ; Unger, K. ; Walter, F.
Radio(chemo)therapy in anal cancer: evaluation of sex-specific disparities across AJCC stages.
Strahlentherapie und Onkologie nn, nn (2025) [10.1007/s00066-025-02368-1]2025
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Lutz, R. (First author) ; Poos, A. (First author) ; Solé-Boldo, L. ; John, L. (First author) ; Wagner, J. ; Prokoph, N. ; Baertsch, M. A. ; Vonficht, D. ; Palit, S. ; Brobeil, A. ; Mechtersheimer, G. ; Hildenbrand, N. ; Hemmer, S. ; Steiger, S. ; Horn, S. ; Pepke, W. ; Spranz, D. M. ; Rehnitz, C. ; Sant, P. ; Mallm, J.-P. ; Friedrich, M. J. ; Reichert, P. ; Huhn, S. ; Trumpp, A. ; Rippe, K. ; Haghverdi, L. ; Fröhling, S. ; Müller-Tidow, C. ; Hübschmann, D. ; Goldschmidt, H. ; Willimsky, G. ; Sauer, S. ; Raab, M. S. ; Haas, S. ; Weinhold, N. (Last author)
Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma.
Science immunology 10(104), eadp6667 (2025) [10.1126/sciimmunol.adp6667]2025
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Ceranski, A. K. (First author) ; Carreño-Gonzalez, M. J. ; Ehlers, A. C. ; Hanssen, K. M. ; Gmelin, N. ; Geyer, F. H. ; Kolodynska, Z. ; Vinca, E. ; Faehling, T. ; Poeller, P. ; Ohmura, S. ; Cidre-Aranaz, F. ; Schulze, A. ; Grünewald, T. (Last author)
Refined culture conditions with increased physiological relevance uncover oncogene-dependent metabolic signatures in Ewing sarcoma spheroids.
Cell reports / Methods nn, nn (2025) [10.1016/j.crmeth.2025.100966]2025
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Guberina, M. ; Stuschke, M. ; Flühs, D. ; Jabbarli, L. ; Kiefer, T. ; Biewald, E. ; Rating, P. ; Manke, H. ; Dalbah, S. ; Hoffmann, C. ; Guberina, N. ; Pöttgen, C. ; Fiorentzis, M. ; Foerster, A. ; Grunewald, T. ; Bornfeld, N. ; Sauerwein, W. ; Bechrakis, N. ; Sokolenko, E.
Dose response relation for optic nerve atrophy at low-dose rate brachytherapy of uveal melanoma.
Radiotherapy and oncology nn, nn (2025) [10.1016/j.radonc.2025.110775]2025
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Hinterberger, A. ; Trupka, L. ; Kortbein, S. ; Ebner, R. ; Fink, N. ; Froelich, M. F. ; Nörenberg, D. ; Wängler, C. ; Wängler, B. ; Schirrmacher, R. ; Holzgreve, A. ; Brendel, M. ; Corradini, S. ; Auernhammer, C. ; Rübenthaler, J. ; Grawe, F.
Structured reporting of neuroendocrine tumors in PET/CT using [18F]SiTATE - impact on interdisciplinary communication.
Scientific reports 15(1), 4793 (2025) [10.1038/s41598-025-88999-x]2025
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Moraitis, A. ; Kahl, T. ; Kandziora, J. ; Jentzen, W. ; Kersting, D. ; Püllen, L. ; Reis, H. ; Köllermann, J. ; Kesch, C. ; Krafft, U. ; Hadaschik, B. A. ; Zaidi, H. ; Herrmann, K. ; Barbato, F. ; Fendler, W. P. ; Darr, C. ; Fragoso Costa, P.
Evaluation of Surgical Margins with Intraoperative PSMA PET/CT and Their Prognostic Value in Radical Prostatectomy.
Journal of nuclear medicine nn, nn (2025) [10.2967/jnumed.124.268719]2025
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Schwarz, F. M. ; Klotz, D. M. ; Yang, R. ; Brux, M. ; Buchholz, F. ; Harb, H. ; Link, T. ; Wimberger, P. ; Theis, M. ; Kuhlmann, J. D.
Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C.
Cancer gene therapy nn, nn (2025) [10.1038/s41417-025-00874-z]2025
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Wald, T. (First author) ; Hamm, B. (First author) ; Holzschuh, J. ; El Shafie, R. ; Kudak, A. ; Kovacs, B. ; Pflüger, I. ; von Nettelbladt, B. ; Ulrich, C. ; Baumgartner, M. ; Vollmuth, P. ; Debus, J. ; Maier-Hein, K. ; Welzel, T.
Enhancing deep learning methods for brain metastasis detection through cross-technique annotations on SPACE MRI.
European radiology experimental 9(1), 15 (2025) [10.1186/s41747-025-00554-5]2025
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Larrain, C. ; Pu, T. ; Cox, P. ; Sprott, K. ; Blakely, A. M. ; Bauer, S. ; George, S.
INSIGHT: A Phase III Trial of Ripretinib Versus Sunitinib in Patients with Advanced GIST with KIT Exon 11 and Exon 17/18 Mutations Who Were Previously Treated with Imatinib.
Annals of surgical oncology nn, nn (2025) [10.1245/s10434-024-16853-x]2025
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Li, M. J. ; Meyer, L. C. ; Meier, N. ; Witte, J. ; Maldacker, M. ; Seredynska, A. ; Schueler, J. ; Schilling, O. ; Föll, M. C.
Spatial Proteomics by Parallel Accumulation-Serial Fragmentation Supported MALDI MS/MS Imaging: A First Glance Into Multiplexed and Spatial Peptide Identification.
Rapid communications in mass spectrometry 39(9), e10006 (2025) [10.1002/rcm.10006]2025
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Ehret, F. ; Bhandarkar, A. R. ; Chisam, M. ; Goulenko, V. ; Kumar, R. ; Fekrmandi, F. ; Skalina, K. A. ; Kresl, J. ; Lo, S. S. ; Gibbs, I. C. ; Soltys, S. G. ; Sheehan, J. P. ; Fürweger, C. ; Slotman, B. J. ; Shih, H. A. ; Chao, S. T.
Stereotactic Radiosurgery for Vestibular Schwannoma - A Case-Based Practice Guide from the Radiosurgery Society.
Practical Radiation Oncology nn, nn (2025) [10.1016/j.prro.2025.01.010]2025
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Desaulniers, M. ; Rousseau, É. ; Pabst, K. M.
Clinical and Research Applications of FAPI Tracers: A Review.
BJR nn, nn (2025) [10.1093/bjr/tqaf020]2025
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Trautwein, N. F. ; Calderón, E. ; Linder, P. M. ; Reischl, G. ; Driessen, P. ; Lan, W. ; Brendlin, A. S. ; Groß, T. ; Dittmann, H. ; Hinterleitner, M. ; la Fougère, C. ; Schmidt, F. P. ; Kiefer, L. S.
Low-activity [18F]-somatostatin receptor (SSTR) imaging using [18F]SiTATE on a long axial field-of-view PET/CT scanner.
EJNMMI Physics 12(1), 13 (2025) [10.1186/s40658-025-00720-z]2025
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Roberti, M. P. (First author) ; Charoentong, P. ; Lyu, Y. ; Meyer, M. ; Eichmüller, S. ; Schmidt, P. ; Momburg, F. ; Cetin, M. ; Hartmann, F. ; Valous, N. ; Stenzinger, A. ; Michel, L. ; Lichter, P. ; Schneeweiss, A. ; Thewes, V. ; Fremd, C. ; Zörnig, I. ; Jäger, D. (Last author)
Isolation of a tumor neoantigen specific CD8+ TCR from a skin biopsy of a vaccination site.
OncoImmunology 14(1), 2457793 (2025) [10.1080/2162402X.2025.2457793]2025
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Stintzing, S. ; Klein-Scory, S. ; Fischer von Weikersthal, L. ; Fuchs, M. ; Kaiser, F. ; Heinrich, K. ; Modest, D. P. ; Hofheinz, R.-D. ; Decker, T. ; Gerger, A. ; Angermeier, S. ; Rumpold, H. ; Dickhut, A. ; Öhler, L. ; Gruenberger, B. ; Niedersuess-Beke, D. ; Sandmann, M. ; Winder, T. ; Trojan, J. ; Prager, G. ; Held, S. ; Kumbrink, J. ; Schmiegel, W. ; Baraniskin, A. ; Heinemann, V.
Baseline Liquid Biopsy in Relation to Tissue-Based Parameters in Metastatic Colorectal Cancer: Results From the Randomized FIRE-4 (AIO-KRK-0114) Study.
Journal of clinical oncology nn, nn (2025) [10.1200/JCO.24.01174]2025
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Saiag, P. ; Lebbe, C. ; Brochez, L. ; Emile, J.-F. ; Forsea, A. M. ; Harwood, C. ; Hauschild, A. ; Italiano, A. ; Kandolf, L. ; Kelleners-Smeets, N. W. ; Lallas, A. ; Leiter, U. ; Llombart, B. ; Longo, C. ; Malvehy, J. ; Mijuskovic, Z. ; Moreno-Ramirez, D. ; Mosterd, K. ; Tagliaferri, L. ; Ugurel, S. ; Vieira, R. ; Zalaudek, I. ; Garbe, C.
Diagnosis and treatment of dermatofibrosarcoma protuberans. European interdisciplinary guideline - update 2024.
European journal of cancer 218, 115265 (2025) [10.1016/j.ejca.2025.115265]2025
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Velz, J. ; Freudenmann, L. ; Medici, G. ; Dubbelaar, M. ; Mohme, M. ; Ghasemi, D. R. ; Scheid, J. ; Kowalewski, D. J. ; Patterson, A. B. ; Zeitlberger, A. M. ; Lamszus, K. ; Westphal, M. ; Eyrich, M. ; Messing-Jünger, M. ; Röhrig, A. ; Reinhard, H. ; Beccaria, K. ; Craveiro, R. B. ; Frey, B. M. ; Sill, M. ; Nahnsen, S. ; Gauder, M. ; Kapolou, K. ; Silginer, M. ; Weiss, T. ; Wirsching, H.-G. ; Roth, P. ; Grotzer, M. ; Krayenbühl, N. ; Bozinov, O. ; Regli, L. ; Rammensee, H.-G. ; Rushing, E. J. ; Sahm, F. ; Walz, J. ; Weller, M. ; Neidert, M. C.
Mapping naturally presented T cell antigens in medulloblastoma based on integrative multi-omics.
Nature Communications 16(1), 1364 (2025) [10.1038/s41467-025-56268-0]2025
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Lee, S. ; Yu, Y. ; Trimpert, J. ; Benthani, F. ; Mairhofer, M. ; Richter-Pechanska, P. ; Wyler, E. ; Belenki, D. ; Kaltenbrunner, S. ; Pammer, M. ; Kausche, L. ; Firsching, T. C. ; Dietert, K. ; Schotsaert, M. ; Martínez-Romero, C. ; Singh, G. ; Kunz, S. ; Niemeyer, D. ; Ghanem, R. ; Salzer, H. J. F. ; Paar, C. ; Mülleder, M. ; Uccellini, M. ; Michaelis, E. G. ; Khan, A. ; Lau, A. ; Schönlein, M. ; Habringer, A. ; Tomasits, J. ; Adler, J. M. ; Kimeswenger, S. ; Gruber, A. D. ; Hoetzenecker, W. ; Steinkellner, H. ; Purfürst, B. ; Motz, R. ; Di Pierro, F. ; Lamprecht, B. ; Osterrieder, N. ; Landthaler, M. ; Drosten, C. ; García-Sastre, A. ; Langer, R. ; Ralser, M. ; Eils, R. ; Reimann, M. ; Fan, D. N. Y. ; Schmitt, C. A.
Author Correction: Virus-induced senescence is a driver and therapeutic target in COVID-19.
Nature nn, nn (2025) [10.1038/s41586-025-08718-4]2025
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Aldape, K. ; Capper, D. ; von Deimling, A. ; Giannini, C. ; Gilbert, M. R. ; Hawkins, C. ; Hench, J. ; Jacques, T. S. ; Jones, D. ; Louis, D. N. ; Mueller, S. ; Orr, B. A. ; Nasrallah, M. ; Pfister, S. ; Sahm, F. ; Snuderl, M. ; Solomon, D. ; Varlet, P. ; Wesseling, P.
cIMPACT-NOW update 9: Recommendations on utilization of genome-wide DNA methylation profiling for central nervous system tumor diagnostics.
Neuro-oncology advances 7(1), vdae228 (2025) [10.1093/noajnl/vdae228]2025
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Pfeuffer, L. ; Siegert, V. ; Trozzo, R. ; Steiger, K. ; Rad, R. ; Ruland, J. ; Buchner, M.
Autoimmunity promotes chronic lymphocytic leukemia progression in an indolent disease model.
Scientific reports 15(1), 4117 (2025) [10.1038/s41598-025-86876-1]2025
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Hinz, F. (First author) ; Friedel, D. ; Korshunov, A. ; Ippen, F. ; Bogumil, H. ; Banan, R. ; Brandner, S. ; Hasselblatt, M. ; Boldt, H. B. ; Dirse, V. ; Dohmen, H. ; Aronica, E. ; Brodhun, M. ; Broekman, M. L. D. ; Capper, D. ; Cherkezov, A. ; Deng, M. Y. ; van Dis, V. ; Felsberg, J. ; Frank, S. ; French, P. J. ; Gerlach, R. ; Göbel, K. ; Goold, E. ; Hench, J. ; Kantelhardt, S. ; Kohlhof-Meinecke, P. ; Krieg, S. ; Mawrin, C. ; Morrison, G. ; Mühlebner, A. ; Ozduman, K. ; Pfister, S. ; Poliani, P. L. ; Prinz, M. ; Reifenberger, G. ; Riemenschneider, M. J. ; Sankowski, R. ; Schrimpf, D. ; Sill, M. ; Snuderl, M. ; Verdijk, R. M. ; Voisin, M. R. ; Wesseling, P. ; Wick, W. ; Reuss, D. E. ; von Deimling, A. ; Sahm, F. ; Maas, S. L. N. ; Suwala, A. K. (Last author)
IDH-mutant astrocytomas with primitive neuronal component have a distinct methylation profile and a higher risk of leptomeningeal spread.
Acta neuropathologica 149(1), 12 (2025) [10.1007/s00401-025-02849-8]2025
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Fu, R. (First author) ; Chen, X. (First author) ; Seum, T. ; Hoffmeister, M. ; Brenner, H. (Last author)
Alcohol consumption, polygenic risk score and the risk of colorectal neoplasia.
JNCI cancer spectrum nn, nn (2025) [10.1093/jncics/pkaf017]2025
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Sharma, S. ; Sauter, R. ; Hotze, M. ; Prowatke, A. M. P. ; Niere, M. ; Kipura, T. ; Egger, A.-S. ; Thedieck, K. ; Kwiatkowski, M. ; Ziegler, M. ; Heiland, I.
GEMCAT-a new algorithm for gene expression-based prediction of metabolic alterations.
NAR: genomics and bioinformatics 7(1), lqaf003 (2025) [10.1093/nargab/lqaf003]2025
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Kobold, S.
RORing CAR T Cells in Solid and Hematologic Cancers: Same but Different.
Clinical cancer research 31(3), 437 - 438 (2025) [10.1158/1078-0432.CCR-24-3688]2025
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Acker, F. ; Reck, M. ; Martin, D. ; Rieken, S. ; Heinzen, S. ; Rost, M. ; Aguinarte, L. ; Schulte, H. ; Serve, H. ; Oellerich, T. ; Sebastian, M. ; Althoff, F. C.
Efficacy and safety of immune checkpoint inhibition combined with concurrent chemoradiotherapy in patients with stage III unresectable non-small cell lung cancer: A systematic review and meta-analysis.
European journal of cancer 218, 115266 (2025) [10.1016/j.ejca.2025.115266]2025
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Friker, L. L. ; Perwein, T. ; Waha, A. ; Dörner, E. ; Klein, R. ; Blattner-Johnson, M. ; Layer, J. P. ; Sturm, D. ; Nussbaumer, G. ; Kwiecien, R. ; Spier, I. ; Aretz, S. ; Kerl, K. ; Hennewig, U. ; Rohde, M. ; Karow, A. ; Bluemcke, I. ; Schmitz, A. K. ; Reinhard, H. ; Hernáiz Driever, P. ; Wendt, S. ; Weiser, A. ; Guerreiro Stücklin, A. S. ; Gerber, N. U. ; von Bueren, A. O. ; Khurana, C. ; Jorch, N. ; Wiese, M. ; Kratz, C. P. ; Eyrich, M. ; Karremann, M. ; Herrlinger, U. ; Hölzel, M. ; Jones, D. T. W. ; Hoffmann, M. ; Pietsch, T. ; Gielen, G. H. ; Kramm, C. M.
MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma.
Acta neuropathologica 149(1), 11 (2025) [10.1007/s00401-025-02846-x]2025
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Gandaglia, G. ; Barletta, F. ; Scuderi, S. ; Scilipoti, P. ; Rajwa, P. ; Huebner, N. A. ; Gomez Rivas, J. ; Ibanez, L. ; Soeterik, T. F. W. ; Bianchi, L. ; Mattei, A. ; Kesch, C. ; Darr, C. ; Guo, H. ; Zhuang, J. ; Zattoni, F. ; Fendler, W. P. ; Marra, G. ; Stabile, A. ; Robesti, D. ; Amparore, D. ; Joniau, S. ; Schiavina, R. ; Sierra, J. M. ; Porpiglia, F. ; Picchio, M. ; Chiti, A. ; Mottrie, A. ; van den Bergh, R. C. N. ; Shariat, S. F. ; Montorsi, F. ; Briganti, A.
External Validation of Nomograms for the Identification of Pelvic Nodal Dissection Candidates Among Prostate Cancer Patients with Negative Preoperative Prostate-specific Membrane Antigen Positron Emission Tomography.
European urology oncology nn, nn (2025) [10.1016/j.euo.2025.01.004]2025
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Adler, T. (First author) ; Nölke, J.-H. (First author) ; Reinke, A. ; Tizabi, M. D. ; Gruber, S. ; Trofimova, D. ; Ardizzone, L. ; Jaeger, P. F. ; Buettner, F. ; Köthe, U. ; Maier-Hein, L. (Last author)
Application-driven validation of posteriors in inverse problems.
Medical image analysis 101, 103474 (2025) [10.1016/j.media.2025.103474]2025
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Fleischmann, D. ; Gajdi, L. ; Belka, C. ; Niyazi, M.
Response to the letter to the editor of M. M. Hanilce et al. Regarding the article 'Re-irradiation treatment regimens for patients with recurrent glioma - Evaluation of the optimal dose and best concurrent therapy'.
Radiotherapy and oncology 205, 110766 (2025) [10.1016/j.radonc.2025.110766]2025
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Chih, Y.-C. (First author) ; Dietsch, A. C. ; Koopmann, P. ; Ma, X. ; Agardy, D. A. ; Zhao, B. ; De Roia, A. ; Kourtesakis, A. ; Kilian, M. ; Krämer, C. ; Suwala, A. K. ; Stenzinger, M. ; Boenig, H. ; Blum, A. ; Pienkowski, V. M. ; Aman, K. ; Becker, J. ; Feldmann, H. ; Bunse, T. ; Harbottle, R. ; Riemer, A. ; Liu, H. ; Etminan, N. ; Sahm, F. ; Ratliff, M. ; Wick, W. ; Platten, M. ; Green, E. ; Bunse, L. (Last author)
Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen.
Nature Communications 16(1), 1262 (2025) [10.1038/s41467-025-56547-w]2025
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Yoon, C. H. ; Ross, M. I. ; Gastman, B. R. ; Luke, J. J. ; Ascierto, P. A. ; Long, G. V. ; Rutkowski, P. ; Khattak, M. ; Del Vecchio, M. ; de la Cruz Merino, L. ; Mackiewicz, J. ; Chiarion-Sileni, V. ; Schadendorf, D. ; Carlino, M. S. ; Zhao, Y. ; Fukunaga-Kalabis, M. ; Krepler, C. ; Eggermont, A. M. M. ; Gershenwald, J. E. ; Sondak, V. K.
Adjuvant Pembrolizumab in Stage II Melanoma: Outcomes by Primary Tumor Location in the Randomized, Double-Blind, Phase III KEYNOTE-716 Trial.
Annals of surgical oncology nn, nn (2025) [10.1245/s10434-024-16642-6]2025
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Schmutzer-Sondergeld, M. ; Gencer, A. ; Schmidlechner, T. ; Zimmermann, H. ; Niedermeyer, S. ; Katzendobler, S. ; Stoecklein, V. M. ; Liebig, T. ; Schichor, C. ; Thon, N.
Comparison of surgical approaches and outcome for symptomatic pineal cysts: microscopic/endoscopic fenestration vs. stereotactic catheter implantation.
Acta neurochirurgica 167(1), 27 (2025) [10.1007/s00701-025-06445-3]2025
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Calderón, E. ; Kiefer, L. S. ; Schmidt, F. P. ; Lan, W. ; Brendlin, A. S. ; Reinert, C. P. ; Singer, S. ; Reischl, G. ; Hinterleitner, M. ; Dittmann, H. ; la Fougère, C. ; Trautwein, N. F.
One-day dual-tracer examination in neuroendocrine neoplasms: a real advantage of low activity LAFOV PET imaging.
European journal of nuclear medicine and molecular imaging nn, nn (2025) [10.1007/s00259-025-07073-w]2025
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Jia, Y. ; Wang, S. ; Urban, S. ; Müller, J. M. ; Sum, M. ; Wang, Q. ; Bauer, H. ; Schulte, U. ; Rampelt, H. ; Pfanner, N. ; Schüle, K. M. ; Imhof, A. ; Forné, I. ; Berlin, C. ; Sigle, A. ; Gratzke, C. ; Greschik, H. ; Metzger, E. ; Schüle, R.
Mitochondrial KMT9 methylates DLAT to control pyruvate dehydrogenase activity and prostate cancer growth.
Nature Communications 16(1), 1191 (2025) [10.1038/s41467-025-56492-8]2025
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Keyl, J. ; Keyl, P. ; Montavon, G. ; Hosch, R. ; Brehmer, A. ; Mochmann, L. ; Jurmeister, P. ; Dernbach, G. ; Kim, M. ; Koitka, S. ; Bauer, S. ; Bechrakis, N. ; Forsting, M. ; Führer-Sakel, D. ; Glas, M. ; Grünwald, V. ; Hadaschik, B. ; Haubold, J. ; Herrmann, K. ; Kasper, S. ; Kimmig, R. ; Lang, S. ; Rassaf, T. ; Roesch, A. ; Schadendorf, D. ; Siveke, J. ; Stuschke, M. ; Sure, U. ; Totzeck, M. ; Welt, A. ; Wiesweg, M. ; Baba, H. A. ; Nensa, F. ; Egger, J. ; Müller, K.-R. ; Schuler, M. ; Klauschen, F. ; Kleesiek, J.
Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence.
Nature cancer nn, nn (2025) [10.1038/s43018-024-00891-1]2025
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Ritter, M. (First author) ; Blume, C. ; Tang, Y. ; Patel, A. J. ; Patel, B. ; Berghaus, N. ; Kada Benotmane, J. ; Kueckelhaus, J. ; Yabo, Y. ; Zhang, J. ; Grabis, E. ; Villa, G. ; Zimmer, D. N. ; Khriesh, A. ; Sievers, P. ; Seferbekova, Z. ; Hinz, F. ; Ravi, V. M. ; Seiz-Rosenhagen, M. ; Ratliff, M. ; Herold-Mende, C. ; Schnell, O. ; Beck, J. ; Wick, W. ; von Deimling, A. ; Gerstung, M. ; Heiland, D. H. ; Sahm, F. (Last author)
Spatially resolved transcriptomics and graph-based deep learning improve accuracy of routine CNS tumor diagnostics.
Nature cancer nn, nn (2025) [10.1038/s43018-024-00904-z]2025
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Boeke, S. ; Habrich, J. ; Kübler, S. ; Boldt, J. ; Schick, F. ; Nikolaou, K. ; Kübler, J. ; Gani, C. ; Niyazi, M. ; Zips, D. ; Thorwarth, D.
Longitudinal assessment of diffusion-weighted imaging during magnetic resonance-guided radiotherapy in head and neck cancer.
Radiation oncology 20(1), 15 (2025) [10.1186/s13014-025-02589-9]2025
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Aghamaliyev, U. ; Karimbayli, J. ; Zamparas, A. ; Bösch, F. ; Thomas, M. ; Schmidt, T. ; Krautz, C. ; Kahlert, C. ; Schölch, S. ; Angele, M. K. ; Niess, H. ; Guba, M. O. ; Werner, J. ; Ilmer, M. ; Renz, B. W.
Bots in white coats: are large language models the future of patient education? a multi-center cross-sectional analysis.
International journal of surgery nn, nn (2025) [10.1097/JS9.0000000000002250]2025
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Hollander, J. F. ; Szymansky, A. ; Wünschel, J. ; Astrahantseff, K. ; Rosswog, C. ; Thorwarth, A. ; Thole-Kliesch, T. M. ; Chamorro González, R. ; Hundsdörfer, P. ; Hauptmann, K. ; Schmelz, K. ; Gürgen, D. ; Rogasch, J. M. M. ; Henssen, A. G. ; Fischer, M. ; Schulte, J. ; Eckert, C. ; Eggert, A. ; Lodrini, M. ; Deubzer, H. E.
Serially Quantifying TERT Rearrangement Breakpoints in ctDNA Enables Minimal Residual Disease Monitoring in Patients with Neuroblastoma.
Cancer research communications 5(1), 167 - 177 (2025) [10.1158/2767-9764.CRC-24-0569]2025
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Kameri, E. ; Jepsen, V. H. ; Stachura, P. ; Rüchel, N. ; Bhave, R. ; Benitez, L. ; Crispi, F. ; Gratacos, E. ; Dragano, N. ; Janssen, S. ; Borkhardt, A. ; Pandyra, A. ; Kögler, G. ; Fischer, U.
A gut instinct for childhood leukemia prevention: microbiome-targeting recommendations aimed at parents and caregivers.
Frontiers in Public Health 12, 1445113 (2024) [10.3389/fpubh.2024.1445113]2024
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Müntnich, L. J. ; Dutzmann, C. M. ; Großhennig, A. ; Härter, V. ; Keymling, M. ; Mastronuzzi, A. ; Montellier, E. ; Nees, J. ; Palmaers, N. E. ; Penkert, J. ; Pfister, S. M. ; Ripperger, T. ; Schott, S. ; Silchmüller, F. ; Hainaut, P. ; Kratz, C. P.
Cancer risk in carriers of TP53 germline variants grouped into different functional categories.
JNCI cancer spectrum nn, nn (2025) [10.1093/jncics/pkaf008]2025
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Mascarenhas, L. ; DuBois, S. G. ; Albert, C. M. ; Bielack, S. ; Orbach, D. ; Federman, N. ; Geoerger, B. ; Nagasubramanian, R. ; Zhang, Y. ; Chisholm, J. ; Gallego Melcon, S. ; Goto, H. ; Morgenstern, D. A. ; Owens, C. ; Pappo, A. S. ; Perreault, S. ; Schulte, J. H. ; Shukla, N. ; Zwaan, C. M. ; Neu, N. ; Bernard-Gauthier, V. ; De La Cuesta, E. ; van Tilburg, C. M. (Last author) ; Laetsch, T. W.
Elective Discontinuation of Larotrectinib in Pediatric Patients With TRK Fusion Sarcomas and Related Mesenchymal Tumors.
Journal of clinical oncology nn, nn (2025) [10.1200/JCO.24.00848]2025
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Smirnov, P. (First author) ; Przybilla, M. J. (First author) ; Simovic-Lorenz, M. (First author) ; Parra, R. G. (First author) ; Susak, H. (First author) ; Aichmüller-Ratnaparkhe, M. ; Wong, J. K. ; Körber, V. ; Mallm, J.-P. ; Philippos, G. ; Sill, M. ; Kolb, T. ; Kumar, R. ; Casiraghi, N. ; Okonechnikov, K. ; Ghasemi, D. R. ; Maaß, K. K. ; Pajtler, K. ; Jauch, A. ; Korshunov, A. ; Höfer, T. ; Zapatka, M. ; Pfister, S. ; Huber, W. ; Stegle, O. (Last author) ; Ernst, A. (Last author)
Author Correction: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.
Nature Communications 16(1), 1085 (2025) [10.1038/s41467-025-56164-7]2025
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Able, M. ; Kasper, M.-A. ; Vick, B. ; Schwach, J. ; Gao, X. ; Schmitt, S. ; Tizazu, B. ; Fischer, A. ; Künzl, S. ; Leilich, M. ; Mai, I. ; Ochtrop, P. ; Stengl, A. ; de Geus, M. A. R. ; von Bergwelt-Baildon, M. ; Schumacher, D. ; Helma, J. ; Hackenberger, C. P. R. ; Götze, K. S. ; Jeremias, I. ; Leonhardt, H. ; Feuring, M. ; Spiekermann, K.
Effective eradication of acute myeloid leukemia stem cells with FLT3-directed antibody-drug conjugates.
Leukemia nn, nn (2025) [10.1038/s41375-024-02510-5]2025
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Wolter, L. C. ; Hennings, F. ; Bokor, J. ; Richter, C. ; Stützer, K.
Validity of one-time phantomless patient-specific quality assurance in proton therapy with regard to the reproducibility of beam delivery.
Medical physics nn, nn (2025) [10.1002/mp.17637]2025
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Nieto, A. E. ; Fleischmann, D. ; Unger, K. ; Albrecht, V. ; Maas, J. ; Zitzelsberger, H. ; Belka, C. ; Proescholdt, M. ; Lauber, K. ; Niyazi, M. ; Orth, M.
Targeting VEGF‐A in an Immunocompetent Orthotopic Mouse Model of Mesenchymal Glioblastoma Improves Antitumorigenicity and Decreases Proinflammatory Response in Normal Brain Tissue after Fractionated Radiotherapy
Advanced therapeutics nn, nn (2025) [10.1002/adtp.202400374]2025
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Haebe, S. ; Schuebbe, G. ; Jurmeister, P. ; von Bergwelt-Baildon, M. ; Westphalen, C. B. ; Lauer, U. M. ; Kunz, W. G. ; Subklewe, M. ; Weigert, O.
Adding checkpoint inhibitors to first-line chemotherapy for NUT carcinoma patients.
npj precision oncology 9(1), 26 (2025) [10.1038/s41698-024-00768-7]2025
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Wong, F. C. ; Merker, S. R. ; Bauer, L. ; Han, Y. ; Le, V. M. H. ; Wenzel, C. ; Böthig, L. ; Heiduk, M. ; Drobisch, P. ; Rao, V. S. ; Malekian, F. ; Mansourkiaei, A. ; Sperling, C. ; Polster, H. ; Pecqueux, M. ; Istvanffy, R. ; Ye, L. ; Kong, B. ; Aust, D. E. ; Baretton, G. ; Seifert, L. ; Seifert, A. M. ; Weitz, J. ; Demir, I. E. ; Kahlert, C.
Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration.
British journal of cancer 132(4), 326-339 (2025) [10.1038/s41416-024-02915-0]2025
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Brombacher, E. ; Schilling, O. ; Kreutz, C.
Characterizing the omics landscape based on 10,000+ datasets.
Scientific reports 15(1), 3189 (2025) [10.1038/s41598-025-87256-5]2025
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Seitz, S. ; Dreyer, T. F. ; Stange, C. ; Steiger, K. ; Wohlleber, D. ; Anton, M. ; Pham, T. A. ; Sauter-Peschke, D. ; Reuning, U. ; Multhoff, G. ; Weichert, W. ; Kiechle, M. ; Magdolen, V. ; Bronger, H.
The chemokine CX3CL1 promotes intraperitoneal tumour growth despite enhanced T-cell recruitment in ovarian cancer.
Neoplasia 60, 101130 (2025) [10.1016/j.neo.2025.101130]2025
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Graf, M. ; Ziegelmayer, S. ; Reischl, S. ; Teumer, Y. ; Gassert, F. T. ; Marka, A. W. ; Raffler, P. ; Bachmann, J. ; Makowski, M. ; Reim, D. ; Lohöfer, F. ; Burian, E. ; Braren, R.
CT-Derived Quantitative Image Features Predict Neoadjuvant Treatment Response in Adenocarcinoma of the Gastroesophageal Junction with High Accuracy.
Cancers 17(2), 216 (2025) [10.3390/cancers17020216]2025
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Gianno, F. ; Miele, E. ; Sabato, C. ; Ferretti, E. ; Minasi, S. ; Buttarelli, F. R. ; Salerno, D. ; Pediconi, N. ; Pascucci, G. R. ; Guerrieri, F. ; Ciolfi, A. ; Pizzi, S. ; Massimino, M. ; Biassoni, V. ; Schiavello, E. ; Gessi, M. ; Asioli, S. ; Mastronuzzi, A. ; d’Amati, A. ; Catanzaro, G. ; Viscardi, E. ; Capper, D. ; Giangaspero, F. ; Antonelli, M.
MicroRNAs Expression Profile in MN1-Altered Astroblastoma
Biomedicines 13(1), 112 (2025) [10.3390/biomedicines13010112]2025
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Ding, J. (First author) ; Fu, R. ; Yuan, T. ; Brenner, H. ; Hoffmeister, M. (Last author)
Lifestyle scores and their potential to estimate the risk of multiple non-communicable disease-related endpoints: a systematic review.
BMC public health 25(1), 293 (2025) [10.1186/s12889-025-21537-6]2025
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Dukaczewska, A. ; Marticorena Garcia, S. R. ; Ponsel, S. ; Webster, A. ; Butz, F. ; Dobrindt, E. M. ; Pratschke, J. ; Horst, D. ; Mogl, M. T. ; Kunze, C. A.
Necrosis in Preoperative Cross-Sectional Imaging and Postoperative Histology Is a Diagnostic Marker for Malignancy of Adrenocortical Tumors.
Current oncology 32(1), 25 (2025) [10.3390/curroncol32010025]2025
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El-Marouk, K. ; Käsmann, L.
Langzeitergebnisse der IMRT vs. 3D-konformalen Radiotherapie beim lokal fortgeschrittenem, inoperablem nicht-kleinzelligem Lungenkarzinom (NSCLC). [Longterm outcome of definitive radiotherapy using IMRT vs. 3D-CRT in locally advanced, inoperable non-small cell lung cancer (NSCLC)]
Strahlentherapie und Onkologie 201(2), 198 - 200 (2025) [10.1007/s00066-024-02327-2]2025
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Lee, M. A. ; Hatcher, C. A. ; Hazelwood, E. ; Goudswaard, L. J. ; Tsilidis, K. K. ; Vincent, E. E. ; Martin, R. M. ; Smith-Byrne, K. ; Brenner, H. ; Cheng, I. ; Kweon, S.-S. ; Le Marchand, L. ; Newcomb, P. A. ; Schoen, R. E. ; Peters, U. ; Gunter, M. J. ; Van Guelpen, B. ; Murphy, N.
A proteogenomic analysis of the adiposity colorectal cancer relationship identifies GREM1 as a probable mediator.
International journal of epidemiology 54(1), dyae175 (2025) [10.1093/ije/dyae175]2025
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Dehner, C. ; Pissaloux, D. ; Thamphya, B. ; Tirode, F. ; Von Deimling, A. ; Guo, R. R. ; Wieland, C. ; de la Fouchardière, A. ; Kervarrec, T.
ACTB::ZMIZ2-rearranged adnexal carcinoma: a second case.
Virchows Archiv nn, nn (2025) [10.1007/s00428-025-04030-8]2025
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Bremer, J. ; Franco, P. ; Menstell, J. A. ; Tey, S. ; Zajt, K. K. ; Popzhelyazkova, K. ; Nolte, K. ; Schlegel, J. ; Pedro, M. T. ; Osterloh, A. ; Delev, D. ; Hohenhaus, M. ; Scholz, C. ; Schnell, O. ; Beck, J. ; Weis, J. ; Heiland, D. H.
Spatially resolved transcriptomics of benign and malignant peripheral nerve sheath tumors.
Neuro-Oncology nn, nn (2025) [10.1093/neuonc/noaf016]2025
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Rosnev, S. ; Sterner, B. ; Schiele, P. ; Kolling, S. ; Martin, M. ; Flörcken, A. ; Erber, B. ; Wittenbecher, F. ; Kofla, G. ; Kurreck, A. ; Lang, T. J. L. ; von Einem, J. C. ; de Santis, M. ; Pelzer, U. ; Stintzing, S. ; Bullinger, L. ; Klinghammer, K. ; Geisel, D. ; Ochsenreither, S. ; Frentsch, M. ; Na, I.-K.
Reduced monocytic IL10 expression in PD1 inhibitor-treated patients is a harbinger of severe immune-related adverse events.
European journal of cancer 217, 115252 (2025) [10.1016/j.ejca.2025.115252]2025
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Williams, H. ; Fokas, E. ; Diefenhardt, M. ; Lee, C. ; Verheij, F. S. ; Omer, D. M. ; Lin, S. T. ; Dunne, R. F. ; Marcet, J. ; Cataldo, P. ; Polite, B. ; Piso, P. ; Polat, B. ; Dapper, H. ; Ghadimi, M. ; Hofheinz, R. D. ; Qin, L.-X. ; Saltz, L. B. ; Wu, A. J. ; Gollub, M. J. ; Smith, J. J. ; Weiser, M. R. ; Rödel, C. ; Garcia-Aguilar, J. ; Group, G. R. C. S. (Collaboration Author) ; Consortium, O. (Collaboration Author)
Survival Among Patients Treated with Total Mesorectal Excision or Selective Watch-and-Wait After Total Neoadjuvant Therapy: A Pooled Analysis of the CAO/ARO/AIO-12 and OPRA Randomized Phase II Trials.
Annals of oncology nn, nn (2025) [10.1016/j.annonc.2025.01.006]2025
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Veit-Haibach, P. ; Herrmann, K. ; Zimmermann, R. ; Hustinx, R.
Green Nuclear Medicine and Radiotheranostics.
Journal of nuclear medicine nn, nn (2025) [10.2967/jnumed.124.268928]2025
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Bauer, F. (First author) ; Kächele, J. ; Bernhard, J. ; Hajiyianni, M. ; Weinhold, N. ; Sauer, S. ; Grözinger, M. ; Raab, M.-S. ; Mai, E. K. ; Weber, T. F. ; Goldschmidt, H. ; Schlemmer, H.-P. ; Maier-Hein, K. ; Delorme, S. ; Neher, P. ; Wennmann, M. (Last author)
Advanced Automated Model for Robust Bone Marrow Segmentation in Whole-body MRI.
Academic radiology nn, nn (2025) [10.1016/j.acra.2024.12.060]2025
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Hernandez-Solarte, D. (First author) ; Schröder, L. (Last author)
RF Heating Effects in CEST NMR with Hyperpolarized 129Xe Considering Different Spin Exchange Kinetics and Saturation Schemes.
ChemPhysChem nn, nn (2025) [10.1002/cphc.202401037]2025
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Schulz, T. ; Gontla, R. ; Teuber, A. ; Beerbaum, M. ; Fletcher, B. S. ; Mühlenberg, T. ; Kaitsiotou, H. ; Hardick, J. ; Jeyakumar, K. ; Keul, M. ; Müller, M. P. ; Sievers, S. ; Bauer, S. ; Rauh, D.
Design, Synthesis, and SAR of Covalent KIT and PDGFRA Inhibitors─Exploring Their Potential in Targeting GIST.
Journal of medicinal chemistry 68(3), 3238-3259 (2025) [10.1021/acs.jmedchem.4c02472]2025
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Krauss, T. ; Gürcinar, I. H. ; Bourquain, U. ; Hieber, M. ; Krohmer, E. N. ; Wu, N. ; Tokalov, S. ; Goess, R. ; Reyes, C. M. ; Saur, D. ; Friess, H. ; Ceyhan, G. O. ; Demir, I. E. ; Safak, O.
Pancreatic cancer cells infiltrate nerves through TGFbeta1-driven perineural epithelial-to-mesenchymal-like transdifferentiation.
Neoplasia 60, 101126 (2025) [10.1016/j.neo.2025.101126]2025
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Le Rhun, E. ; Bink, A. ; Felsberg, J. ; Gramatzki, D. ; Brandner, S. ; Benhamida, J. K. ; Wick, A. ; Tonn, J. C. ; Mohme, M. ; Tabatabai, G. ; Capper, D. ; Snuderl, M. ; Razis, E. ; Ronellenfitsch, M. W. ; Neidert, N. ; Ng, H.-K. ; Pohl, U. ; Bale, T. ; Quach, S. ; Rieger, D. ; Schüller, U. ; Onken, J. ; Drüschler, K. ; Maurage, C.-A. ; Regli, L. ; Healy, E. ; Graham, M. ; Hortobagyi, T. ; Paine, S. ; Bridges, L. ; Lausova, T. ; Medici, V. ; Sievers, P. ; Schrimpf, D. ; Wick, W. ; Sahm, F. ; Reifenberger, G. ; von Deimling, A. (Last author) ; Weller, M. ; Group, H. G. D. S. (Collaboration Author)
The clinical and molecular landscape of diffuse hemispheric glioma, H3 G34-mutant.
Neuro-Oncology nn, nn (2025) [10.1093/neuonc/noaf015]2025
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Palmer, M. A. ; Kirchhoff, R. ; Buerger, C. ; Benatzy, Y. ; Schebb, N. H. ; Brüne, B.
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling.
Cell death & disease 16(1), 39 (2025) [10.1038/s41419-025-07357-x]2025
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Antoniolli, M. ; Solovey, M. ; Hildebrand, J. A. ; Freyholdt, T. ; Strobl, C. D. ; Bararia, D. ; Keay, W. D. ; Adolph, L. ; Heide, M. ; Passerini, V. ; Winter, L. ; Wange, L. ; Enard, W. ; Thieme, S. ; Blum, H. ; Rudelius, M. ; Mergner, J. ; Ludwig, C. ; Bultmann, S. ; Schmidt-Supprian, M. ; Leonhardt, H. ; Subklewe, M. ; von Bergwelt-Baildon, M. ; Colomé-Tatché, M. ; Weigert, O.
ARID1A mutations protect follicular lymphoma from FAS-dependent immune surveillance by reducing RUNX3/ETS1-driven FAS-expression.
Cell death and differentiation nn, nn (2025) [10.1038/s41418-025-01445-3]2025
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Jelgersma, C. ; Alsolivany, J. ; Akkas, G. ; Wasilewski, D. ; Gastl, B. ; Misch, M. ; Capper, D. ; Kaul, D. ; Bullinger, L. ; Vajkoczy, P. ; Onken, J.
Real-world experience with TTFields in glioma patients with emphasis on therapy usage.
Frontiers in oncology 14, 1430793 (2025) [10.3389/fonc.2024.1430793]2025
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Huebner, H. ; Wimberger, P. ; Laakmann, E. ; Ruckhäberle, E. ; Ruebner, M. ; Lehle, S. ; Uhrig, S. ; Ziegler, P. ; Link, T. ; Hack, C. C. ; Belleville, E. ; Faull, I. ; Hausch, M. ; Wallwiener, D. ; Schneeweiss, A. ; Tesch, H. ; Brucker, S. Y. ; Beckmann, M. W. ; Fasching, P. A. ; Müller, V. ; Fehm, T. N.
Cell-free tumor DNA analysis in advanced or metastatic breast cancer patients: mutation frequencies, testing intention, and clinical impact.
Precision clinical medicine 8(1), pbae034 (2025) [10.1093/pcmedi/pbae034]2025
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Höfer, S. ; Frasch, L. ; Brajkovic, S. ; Putzker, K. ; Lewis, J. ; Schürmann, H. ; Leone, V. ; Sakhteman, A. ; The, M. ; Bayer, F. P. ; Müller, J. ; Hamood, F. ; Siveke, J. ; Reichert, M. ; Kuster, B.
Gemcitabine and ATR inhibitors synergize to kill PDAC cells by blocking DNA damage response.
Molecular systems biology nn, nn (2025) [10.1038/s44320-025-00085-6]2025
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Murthy, V. ; Marvaso, G. ; Jereczek-Fossa, B. A. ; Thoma, S. A. ; Vogel, M. ; Schmidt-Hegemann, N.-S. ; Shelan, M. ; Siva, S. ; Hoelscher, T. ; Kishan, A. U. ; Peeken, J. C. ; Gillessen, S. ; Guckenberger, M. ; Herrmann, K. ; Fendler, W. P. ; Zilli, T. ; Spohn, S. K. B. ; Zamboglou, C.
The Co-IMPACT Consortium: Integrating Prostate-specific Membrane Antigen Positron Emission Tomography and Radiotherapy in Prostate Cancer Care.
European urology nn, nn (2025) [10.1016/j.eururo.2025.01.003]2025
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Bernhardt, M. ; Rech, A. ; Berthold, M. ; Lappe, M. ; Herbel, J.-N. ; Erhard, F. ; Paschen, A. ; Schilling, B. ; Schlosser, A.
SILAC-based quantification reveals modulation of the immunopeptidome in BRAF and MEK inhibitor sensitive and resistant melanoma cells.
Frontiers in immunology 15, 1490821 (2025) [10.3389/fimmu.2024.1490821]2025
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Jin, J. X. (First author) ; Fuchslocher, F. ; Carreno-Gonzalez, M. ; Zahnow, F. ; Ceranski, A. K. ; Will, R. ; Helm, D. ; Bestvater, F. ; Banito, A. ; Imle, R. ; Ohmura, S. ; Cidre-Aranaz, F. ; Grünewald, T. (Last author)
Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in epithelioid sarcoma.
Cancer communications nn, nn (2025) [10.1002/cac2.12665]2025
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Nascentes Melo, L. M. ; Cansiz, F. ; Tasdogan, A.
Aldolase A: the broker of glycolysis.
Nature metabolism nn, nn (2025) [10.1038/s42255-024-01202-9]2025
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Haydo, A. ; Schmidt, J. ; Crider, A. ; Kögler, T. ; Ertl, J. ; Hehlgans, S. ; Hoffmann, M. E. ; Rathore, R. ; Güllülü, Ö. ; Wang, Y. ; Zhang, X. ; Herold-Mende, C. ; Pampaloni, F. ; Tegeder, I. ; Dikic, I. ; Dai, M. ; Rödel, F. ; Kögel, D. ; Linder, B.
BRAT1 - a new therapeutic target for glioblastoma.
Cellular and molecular life sciences 82(1), 52 (2025) [10.1007/s00018-024-05553-0]2025
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De Mendoza, A. M. ; Michlíková, S. ; Castro, P. S. ; Muñoz, A. G. ; Eckhardt, L. ; Lange, S. ; Kunz-Schughart, L. A.
Generalized, sublethal damage-based mathematical approach for improved modeling of clonogenic survival curve flattening upon hyperthermia, radiotherapy, and beyond.
Physics in medicine and biology 70(2), 025022 (2025) [10.1088/1361-6560/ada680]2025
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Schwalm, M. P. ; Knapp, S.
Single-plate kinome screening in live-cells to enable highly cost-efficient kinase inhibitor profiling.
SLAS discovery nn, nn (2025) [10.1016/j.slasd.2025.100214]2025
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Grunewald, L. ; Andersch, L. ; Helmsauer, K. ; Schwiebert, S. ; Klaus, A. ; Henssen, A. G. ; Straka, T. ; Lodrini, M. ; Wicha, S. G. ; Fuchs, S. ; Hertwig, F. ; Westermann, F. ; Vitali, A. ; Caramel, C. ; Büchel, G. ; Eilers, M. ; Astrahantseff, K. ; Eggert, A. ; Höpken, U. E. ; Schulte, J. H. ; Blankenstein, T. ; Anders, K. ; Künkele, A.
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy.
Pharmacological research 212, 107608 (2025) [10.1016/j.phrs.2025.107608]2025
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Neumann, J. ; Beckord, J. ; Hesse, H. S. ; Martin, C. ; Mons, C. ; Chur, D. ; Hense, J. ; Tewes, M. ; Teufel, M. ; Skoda, E.-M.
The novel manualized RELIEVE-group treatment for burdened relatives of cancer patients: a feasibility study.
Frontiers in psychology 15, 1492219 (2025) [10.3389/fpsyg.2024.1492219]2025
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Schmitt, C. ; Müller, K. J. ; Tiedt, S. ; Kramer, N. ; Manger, I. ; Knauss, S. ; Müller-Jensen, L. ; Huehnchen, P. ; Boehmerle, W. ; Schöberl, F. ; Heinzerling, L. ; von Baumgarten, L.
Increased serum NfL and GFAP levels indicate different subtypes of neurologic immune-related adverse events during treatment with immune checkpoint inhibitors.
International journal of cancer nn, nn (2025) [10.1002/ijc.35328]2025
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Vogel, M. M. E. ; Rauscher, I. ; Gschwend, J. E. ; Hekimsoy, T. ; Gabler, N. ; Olufs, C. ; D'Alessandria, C. ; Peeken, J. C. ; Combs, S. E. ; Eiber, M.
Biochemical failure-free survival of 18F-rhPSMA-7 and 18F-flotufolastat PET-guided salvage radiotherapy for patients with recurrent prostate cancer.
Scientific reports 15(1), 2234 (2025) [10.1038/s41598-024-83074-3]2025
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Kenndoff, S. ; Nieto, A. ; Guggenberger, J. E. ; Taugner, J. ; Mansoorian, S. ; Käsmann, L. ; Schmidt-Hegemann, N.-S. ; Manapov, F. ; Belka, C. ; Eze, C.
Dosimetric Predictors of Acute Radiation Pneumonitis and Esophagitis in Hypofractionated Thoracic Irradiation of Non-Small Cell Lung Cancer Patients With Poor Prognostic Factors
Advances in radiation oncology 10(2), 101682 (2025) [10.1016/j.adro.2024.101682]2025
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Ball, M. ; Romanovsky, E. ; Schnecko, F. ; Kirchner, M. ; Neumann, O. ; Brandt, R. ; Beck, S. ; Seker-Cin, H. ; Kluck, K. ; Ourailidis, I. ; Goldschmid, H. ; Fink, A. ; Volckmar, A.-L. ; Menzel, M. ; Allgäuer, M. ; Schirmacher, P. ; Budczies, J. ; Stenzinger, A. ; Kazdal, D.
Clinical Implementation of a High-Throughput Automated Comprehensive Genomic Profiling Test - TruSight Oncology 500 HT
The journal of molecular diagnostics 27(2), 154 - 162 (2025) [10.1016/j.jmoldx.2024.11.005]2025
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Thomsen, A. R. ; Monroy Ordonez, E. B. ; Henke, M. ; Luka, B. ; Sahlmann, J. ; Schäfer, H. ; Verma, V. ; Schlueter, N. ; Grosu, A.-L. ; Sprave, T.
Evaluating the radiosensitivity of the oral microbiome to predict radiation-induced mucositis in head and neck cancer patients: A prospective trial
Clinical and translational radiation oncology 51, 100915 (2025) [10.1016/j.ctro.2025.100915]2025
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Strantz, C. ; Böhm, D. ; Ganslandt, T. ; Börries, M. ; Metzger, P. ; Pauli, T. ; Blaumeiser, A. ; Scheiter, A. ; Jung, I.-C. ; Christoph, J. ; Manuilova, I. ; Strauch, K. ; Ustjanzew, A. ; Reimer, N. ; Busch, H. ; Unberath, P.
Empowering personalized oncology: evolution of digital support and visualization tools for molecular tumor boards.
BMC medical informatics and decision making 25(1), 29 (2025) [10.1186/s12911-024-02821-8]2025
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Rudalska, R. ; Harbig, J. ; Forster, M. ; Woelffing, P. ; Esposito, A. ; Kudolo, M. ; Botezatu, A. ; Haller, V. ; Janssen, N. ; Holzmayer, S. ; Nahidino, P. ; Trompak, O. ; Pantsar, T. ; Kronenberger, T. ; Yurttas, C. ; Rist, E. ; Weber, A. N. R. ; Dahlke, M. H. ; Ott, G. ; Koenigsrainer, A. ; Rothbauer, U. ; Maerklin, M. ; Muerdter, T. ; Schwab, M. ; Singer, S. ; Zender, L. ; Laufer, S. ; Dauch, D.
First-in-class ultralong-target-residence-time p38α inhibitors as a mitosis-targeted therapy for colorectal cancer.
Nature cancer nn, nn (2025) [10.1038/s43018-024-00899-7]2025
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Safizadeh, F. (First author) ; Mandic, M. ; Hoffmeister, M. ; Brenner, H. (Last author)
Colorectal Cancer and Central Obesity.
JAMA network open 8(1), e2454753 - (2025) [10.1001/jamanetworkopen.2024.54753]2025
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Leiss, S. M. ; Hou, H. X. ; Pigorsch, S. ; Borm, K. ; Peeken, J. ; Schneider, A. ; Combs, S. ; Dinkel, A. ; Bernhardt, D.
Analysis of radiation oncology integration within general practitioners' daily patient care: a cross-sectional survey in Germany.
Strahlentherapie und Onkologie nn, nn (2025) [10.1007/s00066-024-02352-1]2025
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Waibel, P. M. A. ; Glavynskyi, I. ; Fechter, T. ; Mix, M. ; Kind, F. ; Sigle, A. ; Jilg, C. A. ; Gratzke, C. ; Werner, M. ; Schilling, O. ; Bronsert, P. ; Freitag, M. T. ; Zamboglou, C. ; Grosu, A.-L. ; Spohn, S. K. B.
Can PSMA PET detect intratumour heterogeneity in histological PSMA expression of primary prostate cancer? Analysis of [68Ga]Ga-PSMA-11 and [18F]PSMA-1007.
European journal of nuclear medicine and molecular imaging nn, nn (2025) [10.1007/s00259-025-07078-5]2025
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Merz, M. ; Albici, A.-M. ; von Tresckow, B. ; Rathje, K. ; Fenk, R. ; Holderried, T. ; Müller, F. ; Tovar, N. ; Oliver-Cáldes, A. ; Vucinic, V. ; Kharboutli, S. ; Bärmann, B.-N. ; Ayuk, F. ; Platzbecker, U. ; Stölzel, F. ; Schub, N. ; Schmitz, F. ; Fandrei, D. ; Born, P. ; Khandanpour, C. ; Hanoun, C. ; Hörster, K. ; Teichert, M. ; Jeker, B. ; Hoffmann, M. ; Kröger, N. ; de Larrea, C. F. ; Pabst, T. ; Gagelmann, N.
Idecabtagene vicleucel or ciltacabtagene autoleucel for relapsed or refractory multiple myeloma: An international multicenter study.
HemaSphere 9(1), e70070 (2025) [10.1002/hem3.70070]2025
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Wang, G. ; Seidler, N. J. ; Röhm, S. ; Pan, Y. ; Liang, X. J. ; Haarer, L. ; Berger, B.-T. ; Sivashanmugam, S. A. ; Wydra, V. R. ; Forster, M. ; Laufer, S. A. ; Chaikuad, A. ; Gehringer, M. ; Knapp, S.
Probing the Protein Kinases′ Cysteinome by Covalent Fragments
Angewandte Chemie / International edition 64(8), e202419736 (2025) [10.1002/anie.202419736]2025
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Schadendorf, D. ; Dummer, R. ; Flaherty, K. T. ; Robert, C. ; Arance, A. ; de Groot, J. W. B. ; Garbe, C. ; Gogas, H. J. ; Gutzmer, R. ; Krajsová, I. ; Liszkay, L. ; Loquai, C. ; Mandalà, M. ; Yamazaki, N. ; Queirolo, P. ; Guenzel, C. ; Polli, A. ; Thakur, M. ; di Pietro, A. ; Ascierto, P. A.
A plain language summary of the 7-year update from part 1 of the COLUMBUS study: encorafenib and binimetinib for people with BRAF V600-mutant melanoma.
Future oncology nn, nn (2025) [10.1080/14796694.2024.2442851]2025
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Stubenvoll, A. ; Schmidt, M. ; Moeller, J. ; Chango, M. A. L. ; Schultz, C. ; Antoniadou, O. ; Loeffler-Wirth, H. ; Bernhart, S. ; Große, F. ; Thier, B. ; Paschen, A. ; Anderegg, U. ; Simon, J. C. ; Ziemer, M. ; Schoeder, C. T. ; Binder, H. ; Kunz, M.
Single-cell transcriptomics and epigenomics point to CD58-CD2 interaction in controlling primary melanoma growth and immunity.
Cancer communications nn, nn (2025) [10.1002/cac2.12651]2025
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Egea-Rodriguez, S. ; Váraljai, R. ; Nordmann, T. M. ; Lubis, R. ; Philip, M. ; Rambow, F. ; Roesch, A. ; Flaig, M. ; Horn, S. ; Stoll, R. ; Zhao, F. ; Paschen, A. ; Klebl, B. ; Hickson, I. D. ; Schadendorf, D. ; Mann, M. ; Helfrich, I.
RECQL4 affects MHC class II-mediated signalling and favours an immune-evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma.
Clinical and translational medicine 15(1), e70094 (2025) [10.1002/ctm2.70094]2025
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Burkhard-Meier, A. ; Rechenauer, V. V. ; Berclaz, L. M. ; Jurinovic, V. ; Albertsmeier, M. ; Dürr, H. R. ; Güler, S. E. ; Hoberger, M. ; Klein, A. ; Knösel, T. ; Kunz, W. G. ; Schmidt-Hegemann, N.-S. ; Von Bergwelt-Baildon, M. ; Lindner, L. H. ; Di Gioia, D.
Maintenance treatment with trofosfamide in patients with advanced soft tissue sarcoma - a retrospective single-centre analysis.
Acta oncologica 64, 56 - 62 (2025) [10.2340/1651-226X.2025.42356]2025
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Neugebauer, E. ; Walter, S. ; Tan, J. ; Drayman, N. ; Franke, V. ; van Gent, M. ; Pennisi, S. ; Veratti, P. ; Stein, K. S. ; Welker, I. ; Tay, S. ; Verjans, G. M. G. M. ; Timmers, H. T. M. ; Akalin, A. ; Landthaler, M. ; Ensser, A. ; Wyler, E. ; Full, F.
Herpesviruses mimic zygotic genome activation to promote viral replication.
Nature Communications 16(1), 710 (2025) [10.1038/s41467-025-55928-5]2025
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Rüfer, A. ; Nilius, H. ; Hermine, O. ; Niedoszytko, M. ; Oude Elberink, J. N. G. ; Bonadonna, P. ; Shoumariyeh, K. ; Gulen, T. ; Hartmann, K. ; Sabato, V. ; Angelova-Fischer, I. ; Baffoe, D. ; Christen, D. ; Belloni Fortina, A. ; Breynaert, C. ; Brockow, K. ; von Bubnoff, N. ; Bumbea, H. ; van Daele, P. ; Doubek, M. ; Dybedal, I. ; Elena, C. ; Fokoloros, C. ; Górska, A. ; Heizmann, M. ; Jentzsch, M. ; Klein, S. ; Lübke, J. ; Mattsson, M. ; Mulder, A. ; Panse, J. ; Schug, T. D. ; Sciumè, M. ; Stefan, A. ; Sztormowska, M. ; Várkonyi, J. ; Wortmann, F. ; Yavuz, A. S. ; Sperr, M. ; Gotlib, J. ; Reiter, A. ; Triggiani, M. ; Sperr, W. R. ; Valent, P.
Prognostic impact of expression of CD2, CD25, and/or CD30 in/on mast cells in systemic mastocytosis: a registry study of the European Competence Network on Mastocytosis.
Leukemia nn, nn (2025) [10.1038/s41375-024-02504-3]2025
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Tauziède-Espariat, A. ; Simbozel, M. ; Sievers, P. ; Dangouloff-Ros, V. ; Guida, L. ; Blauwblomme, T. ; Beccaria, K. ; Saffroy, R. ; Hasty, L. ; Métais, A. ; Grill, J. ; Guerrini-Rousseau, L. ; Varlet, P.
Pediatric high-grade gliomas with concomitant RB1 and SETD2 alterations and Li-Fraumeni syndrome.
Acta Neuropathologica Communications 13(1), 8 (2025) [10.1186/s40478-024-01885-x]2025
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Hofmann, F. O. ; Sirtl, S. ; Heiliger, C. ; Werner, J.
Patientensicherheit in der palliativen Chirurgie.
Die Chirurgie nn, nn (2025) [10.1007/s00104-024-02202-x]2025
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Büttner, M. ; Böke, S. ; Baumeister, S. ; Bachmann, R. ; Bitzer, M. ; Bösmüller, H. ; Wichmann, D. ; Niyazi, M. ; Gani, C.
Simultaneous integrated boost to lateral pelvic lymph nodes during chemoradiotherapy in high-risk rectal cancer.
Strahlentherapie und Onkologie nn, nn (2025) [10.1007/s00066-024-02354-z]2025
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Stock, S. ; Bücklein, V. L. ; Blumenberg, V. ; Magno, G. ; Emhardt, A.-J. ; Holzem, A. M. E. ; Cordas Dos Santos, D. M. ; Schmidt, C. ; Grießhammer, S. ; Frölich, L. ; Kobold, S. ; von Bergwelt-Baildon, M. ; Rejeski, K. ; Subklewe, M.
Prognostic significance of immune reconstitution following CD19 CAR T-cell therapy for relapsed/refractory B-cell lymphoma.
HemaSphere 9(1), e70062 (2025) [10.1002/hem3.70062]2025
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Priego, N. ; de Pablos-Aragoneses, A. ; Perea-García, M. ; Pieri, V. ; Hernández-Oliver, C. ; Álvaro-Espinosa, L. ; Rojas, A. ; Sánchez, O. ; Steindl, A. ; Caleiras, E. ; García, F. ; García-Martín, S. ; Graña-Castro, O. ; García-Mulero, S. ; Serrano, D. ; Velasco-Beltrán, P. ; Jiménez-Lasheras, B. ; Egia-Mendikute, L. ; Rupp, L. ; Stammberger, A. ; Meinhardt, M. ; Chaachou-Charradi, A. ; Martínez-Saez, E. ; Bertero, L. ; Cassoni, P. ; Mangherini, L. ; Pellerino, A. ; Rudà, R. ; Soffietti, R. ; Al-Shahrour, F. ; Saftig, P. ; Sanz-Pamplona, R. ; Schmitz, M. ; Crocker, S. J. ; Calvo, A. ; Palazón, A. ; RENACER (Collaboration Author) ; Valiente, M.
TIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells.
Cancer discovery 15(1), 179 - 201 (2025) [10.1158/2159-8290.CD-24-0134]2025
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Schorn, S. ; Fritz, A. ; Kaissis, G. ; Gaida, M. M. ; Steiger, K. ; Jäger, C. ; Schlitter, A. M. ; Braren, R. ; Friess, H. ; Demir, I. E. ; Ceyhan, G. O.
Neural invasion severity is a strong predictor of local recurrence in pancreatic ductal adenocarcinoma.
Surgery 180, 109018 (2025) [10.1016/j.surg.2024.109018]2025
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Erickson, N. ; Sulosaari, V. ; Sullivan, E. S. ; Laviano, A. ; van Ginkel-Res, A. ; Remijnse, W. ; Wesseling, J. ; Koepcke, U. ; Weber, N. ; Huebner, J. ; Mathies, V. ; Theurich, S. ; Fey, T.
Nutrition Care in Cancer: An Overlooked Part of Patient-Centered Care.
Seminars in oncology nursing 41(1), 151799 (2025) [10.1016/j.soncn.2024.151799]2025
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Brenner, H. (First author) ; Holland-Letz, T. ; Hoffmeister, M. ; Heisser, T. (Last author)
Accounting for differential exclusions in the NordICC trial discloses stronger-than-reported effects of screening colonoscopy.
Journal of clinical epidemiology nn, nn (2025) [10.1016/j.jclinepi.2025.111669]2025
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Westphalen, C. B.
Unveiling Targets and Resistance in FGFR-Altered Cancers.
Annals of oncology nn, nn (2025) [10.1016/j.annonc.2025.01.002]2025
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Ni, Y. ; Wu, J. ; Liu, F. ; Yi, Y. ; Meng, X. ; Gao, X. ; Xiao, L. ; Zhou, W. ; Chen, Z. ; Chu, P. ; Xing, D. ; Yuan, Y. ; Ding, D. ; Shen, G. ; Yang, M. ; Wu, R. ; Wang, L. ; Melo, L. M. N. ; Lin, S. ; Cheng, X. ; Li, G. ; Tasdogan, A. ; Ubellacker, J. M. ; Zhao, H. ; Fang, S. ; Shen, B.
Deep imaging of LepR+ stromal cells in optically cleared murine bone hemisections.
Bone research 13(1), 6 (2025) [10.1038/s41413-024-00387-9]2025
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Venkataramani, V. (First author) ; Yang, Y. ; Ille, S. ; Suchorska, B. ; Loges, S. ; Tost, H. ; Sahm, F. ; Pfister, S. ; Trumpp, A. ; Krieg, S. M. ; Kuner, T. ; Wick, W. ; Winkler, F. (Last author)
Cancer Neuroscience of Brain Tumors: From Multicellular Networks to Neuroscience-Instructed Cancer Therapies.
Cancer discovery 15(1), 39 - 51 (2025) [10.1158/2159-8290.CD-24-0194]2025
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Ribrag, V. ; Iglesias, L. ; De Braud, F. ; Ma, B. ; Yokota, T. ; Zander, T. ; Spreafico, A. ; Subbiah, V. ; Illert, A. L. ; Tan, D. ; Santoro, A. ; Munster, P. N. ; Suehiro, Y. ; Wang, Y. ; Ji, D.-M. ; Chen, S. ; Beltz, K. ; Suenaga, N. ; Ramkumar, T. ; Luo, F. ; Lai, C. ; Wainberg, Z. A.
A first-in-human phase 1/2 dose-escalation study of MAK683 (EED inhibitor) in patients with advanced malignancies.
European journal of cancer 216, 115122 (2025) [10.1016/j.ejca.2024.115122]2025
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Kerle, I. ; Gross, T. ; Kögler, A. ; Arnold, J. ; Werner, M. ; Eckardt, J.-N. ; Möhrmann, E. E. ; Arlt, M. ; Hutter, B. ; Hüllein, J. ; Richter, D. ; Schneider, M. M. K. ; Hlevnjak, M. ; Möhrmann, L. ; Hanf, D. ; Heilig, C. ; Kreutzfeldt, S. ; Teleanu, M.-V. ; Schröck, E. ; Hübschmann, D. ; Horak, P. ; Heining, C. ; Fröhling, S. ; Glimm, H.
Translational and clinical comparison of whole genome and transcriptome to panel sequencing in precision oncology.
npj precision oncology 9(1), 9 (2025) [10.1038/s41698-024-00788-3]2025
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Kersting, D. ; Borys, K. ; Küper, A. ; Kim, M. ; Haubold, J. ; Goerttler, T. ; Umutlu, L. ; Costa, P. F. ; Kleesiek, J. ; Rischpler, C. ; Nensa, F. ; Herrmann, K. ; Fendler, W. P. ; Weber, M. ; Hosch, R. ; Seifert, R.
Staging of prostate Cancer with ultra-fast PSMA-PET scans enhanced by AI.
European journal of nuclear medicine and molecular imaging nn, nn (2025) [10.1007/s00259-024-07060-7]2025
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Abdullah, A. ; Kumbrink, J. ; Liokatis, P. ; Mock, A. ; Abdullah, A. ; Dewenter, I. ; Obermeier, K. T.
The Role of Glucose-6-Phosphate Dehydrogenase in Skin Cancer Metabolism: A Paradigm Shift in Treatment Approaches.
Cancers 17(1), 48 (2025) [10.3390/cancers17010048]2025
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Stork, T. ; Ranft, A. ; Aigner, C. ; Jurgens, H. ; Ladenstein, R. L. ; Timmermann, B. ; Van den Berg, H. ; Dirksen, U. ; Collaud, S.
Primary Mediastinal Ewing's Sarcoma: Post Hoc Analysis from Two International Multicenter Prospective Randomized Trials.
Cancers 17(1), 118 (2025) [10.3390/cancers17010118]2025
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Haller, V. ; Reiff, C. ; Hamacher, R. ; Kostbade, K. ; Kaths, M. ; Treckmann, J. ; Bertram, S. ; Zaun, Y. ; Bauer, S. ; Falkenhorst, J.
Correction: Overall survival of patients with KIT-mutant metastatic GIST in the era of multiple kinase inhibitor availability.
Journal of cancer research and clinical oncology 151(1), 33 (2025) [10.1007/s00432-024-06056-y]2025
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Guberina, N. ; Guberina, M. ; Alberti, Y. ; Stuschke, M.
Definitive Radiochemotherapie des Ösophaguskarzinoms: etablierte Therapie und neue StandardsDefinitive radiochemotherapy of esophageal cancer: established treatment and new standards
Die Onkologie nn, nn (2025) [10.1007/s00761-024-01645-5]2025
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Lazaro-Navarro, J. ; Alcon, C. ; Dorel, M. ; Alasfar, L. ; Bastian, L. ; Baldus, C. ; Astrahantseff, K. ; Yaspo, M.-L. ; Montero, J. ; Eckert, C.
Inhibiting H3K27 Demethylases Downregulates CREB-CREBBP, Overcoming Resistance in Relapsed Acute Lymphoblastic Leukemia.
Cancer medicine 14(1), 1 - 7 (2025) [10.1002/cam4.70596]2025
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Schiele, P. ; Kolling, S. ; Rosnev, S. ; Junkuhn, C. ; Walter, A. L. ; von Einem, J. C. ; Stintzing, S. ; Schöning, W. ; Sauer, I. M. ; Modest, D. P. ; Heinrich, K. ; Weiss, L. ; Heinemann, V. ; Bullinger, L. ; Frentsch, M. ; Na, I.-K.
Flow Cytometric Assessment of FcγRIIIa-V158F Polymorphisms and NK Cell Mediated ADCC Revealed Reduced NK Cell Functionality in Colorectal Cancer Patients.
Cells 14(1), 32 (2025) [10.3390/cells14010032]2025
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Trapp, C. ; Schmidt-Hegemann, N. ; Keilholz, M. ; Brose, S. F. ; Marschner, S. N. ; Schönecker, S. ; Maier, S. H. ; Dehelean, D.-C. ; Rottler, M. ; Konnerth, D. ; Belka, C. ; Corradini, S. ; Rogowski, P.
Patient- and clinician-based evaluation of large language models for patient education in prostate cancer radiotherapy.
Strahlentherapie und Onkologie nn, nn (2025) [10.1007/s00066-024-02342-3]2025
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Warmbrunn, J. ; Straube, C. ; Haase, H.-U. ; Sinnecker, D. ; Laugwitz, K.-L. ; Combs, S. E. ; Schneider, S. ; Habermehl, D.
Influence of radiotherapy on cardiac implantable devices and leads-a single-institution analysis and critical evaluation of current guidelines.
Strahlentherapie und Onkologie nn, nn (2025) [10.1007/s00066-024-02345-0]2025
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Piroth, M. D. ; Krug, D. ; Baumann, R. ; Strnad, V. ; Borm, K. ; Combs, S. ; Corradini, S. ; Duma, M. N. ; Dunst, J. ; Fastner, G. ; Feyer, P. ; Fietkau, R. ; Harms, W. ; Hehr, T. ; Hörner-Rieber, J. ; Matuschek, C. ; Schmeel, C. ; Budach, W. ; Oncology, B. C. E. P. o. t. G. S. o. R. (Collaboration Author)
Implant-based reconstruction and adjuvant radiotherapy in breast cancer patients-current status and DEGRO recommendations.
Strahlentherapie und Onkologie nn, nn (2025) [10.1007/s00066-024-02334-3]2025
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Zirngibl, F. ; Gebert, P. ; Materne, B. ; Launspach, M. ; Künkele, A. ; Hundsdoerfer, P. ; Cyrull, S. ; Deubzer, H. E. ; Kühl, J.-S. ; Eggert, A. ; Lang, P. ; Oevermann, L. ; von Stackelberg, A. ; Schulte, J.
Everolimus with or without mycophenolate mofetil for GVHD prophylaxis after allogeneic HSCT in children with acute kidney injury - a single-center retrospective analysis.
Transplantation and cellular therapy nn, nn (2025) [10.1016/j.jtct.2025.01.002]2025
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Bourdier, S. ; Fisch, A.-S. ; Alp, K. M. ; Das, R. ; Mertins, P. ; Tinhofer, I.
High Ano1 expression as key driver of resistance to radiation and cisplatin in HPV-negative head and neck squamous cell carcinoma.
Scientific reports 15(1), 1555 (2025) [10.1038/s41598-025-85214-9]2025
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Safizadeh, F. (First author) ; Mandic, M. ; Hoffmeister, M. ; Brenner, H. (Last author)
To what extent is the association between obesity and colorectal cancer risk mediated by systemic inflammation?
Cancer communications nn, nn (2025) [DOI:10.1002/cac2.12659]2025
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Stanger, A. M. ; Arnone, M. ; Hanns, P. ; Kimmich, L. M. ; Kübler, J. ; Gekeler, S. ; Görsch, E. S. ; Kramer, L. ; Baer, M. ; Schroeder, J. C. ; Mills, T. S. ; Konantz, M. ; Rudat, S. ; Lengerke, C.
Recipient sex and donor leukemic cell characteristics determine leukemogenesis in patient-derived models.
Haematologica nn, nn (2025) [10.3324/haematol.2023.284647]2025
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Zu, F. ; Chen, C. ; Geng, Q. ; Li, H. ; Chan, B. ; Luo, G. ; Wu, M. ; Ilmer, M. ; Renz, B. W. ; Bentum-Ennin, L. ; Gu, H. ; Sheng, W.
Smad2 Cooperating with TGIF2 Contributes to EMT and Cancer Stem Cells Properties in Pancreatic Cancer via Co-Targeting SOX2.
International journal of biological sciences 21(2), 524 - 543 (2025) [10.7150/ijbs.102381]2025
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Foltyn-Dumitru, M. ; Rastogi, A. ; Cho, J. ; Schell, M. ; Mahmutoglu, M. A. ; Kessler, T. ; Sahm, F. ; Wick, W. ; Bendszus, M. ; Brugnara, G. ; Vollmuth, P. (Last author)
The potential of GPT-4 advanced data analysis for radiomics-based machine learning models.
Neuro-oncology advances 7(1), vdae230 (2025) [10.1093/noajnl/vdae230]2025
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Müller, J. ; Bayer, F. P. ; Wilhelm, M. ; Schuh, M. G. ; Kuster, B. ; The, M.
PTMNavigator: interactive visualization of differentially regulated post-translational modifications in cellular signaling pathways.
Nature Communications 16(1), 510 (2025) [10.1038/s41467-024-55533-y]2025
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Hoffmann, S. ; Hoffmann, T. ; Potkrajcic, V. ; Deinzer, C. K. W. ; Benzler, K. ; Zender, L. ; Daigeler, A. ; Thiel, J. T.
SarkoLife: quality of life in patients undergoing multimodal soft tissue sarcoma treatment.
World journal of surgical oncology 23(1), 10 (2025) [10.1186/s12957-024-03632-x]2025
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Landry, A. P. ; Wang, J. Z. ; Liu, J. ; Patil, V. ; Gui, C. ; Patel, Z. ; Ajisebutu, A. ; Ellenbogen, Y. ; Wei, Q. ; Singh, O. ; Sosa, J. ; Mansouri, S. ; Wilson, C. ; Cohen-Gadol, A. A. ; Zaazoue, M. A. ; Tabatabai, G. ; Tatagiba, M. ; Behling, F. ; Barnholtz-Sloan, J. S. ; Sloan, A. E. ; Chotai, S. ; Chambless, L. B. ; Rebchuk, A. D. ; Makarenko, S. ; Yip, S. ; Mansouri, A. ; Tsang, D. S. ; Aldape, K. ; Gao, A. ; Meningiomas, I. C. o. (Collaboration Author) ; Nassiri, F. ; Zadeh, G.
Development and validation of a molecular classifier of meningiomas.
Neuro-Oncology nn, nn (2025) [10.1093/neuonc/noae242]2025
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Roth, P. ; Capper, D. ; Calabrese, E. ; Halasz, L. M. ; Jakola, A. S.
Role of the tumor board when prescribing mutant isocitrate dehydrogenase inhibitors to patients with isocitrate dehydrogenase-mutant glioma.
Neuro-oncology practice 12(Suppl 1), i29 - i37 (2025) [10.1093/nop/npae100]2025
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Szychot, E. ; Giraud, G. ; Hargrave, D. ; van Vuurden, D. ; Grill, J. ; Biassoni, V. ; Massimo, M. ; Von Büren, A. O. ; Kebudi, R. ; Gil-da-Costa, M. J. ; van Zanten, S. V. ; Bailey, S. ; Karremann, M. ; Bolle, S. ; Ajithkumar, T. ; Krause, M. ; Lassen-Ramshad, Y. ; Janssens, G. ; Morana, G. ; Löbel, U. ; Avula, S. ; Bison, B. ; Lequin, M. ; Aquilina, K. ; Thomale, U. ; Nilsson, P. ; Hamdeh, S. B. A. ; Pietsch, T. ; Varlet, P. ; Jacques, T. S. ; Wesseling, P. ; Jones, D. ; Tabori, U. ; Das, A. ; Mulligan, D. ; Kozmann, F. ; Kramm, C. M.
European standard clinical practice recommendations for paediatric high-grade gliomas
EJC paediatric oncology 5, 100210 (2025) [10.1016/j.ejcped.2024.100210]2025
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Würth, R. (First author) ; Donato, E. (First author) ; Michel, L. L. ; Saini, M. (First author) ; Becker, L. (First author) ; Cheytan, T. ; Doncevic, D. ; Messmer, T. ; Gutjahr, E. ; Weber, R. ; Klein, C. ; Alborzinia, H. ; Yildiz, U. ; Vogel, V. ; Hlevnjak, M. ; Kozyulina, P. ; Neuberth, S.-J. ; Schwerd-Kleine, P. ; Jakab, S. ; Pfarr, N. ; Angeles, A. ; Laut, A. ; Karpova, D. ; Falcone, M. ; Hardt, O. ; Theek, B. ; Wagner, C. V. ; Becker, M. ; Wagner, S. ; Haselmayr, M. ; Schmitt, A. ; Müller-Tidow, C. ; Riethdorf, S. ; Pantel, K. ; Zapatka, M. ; Sültmann, H. ; Herrmann, C. ; Thewes, V. ; Lichter, P. ; Schneeweiss, A. ; Sprick, M. (Last author) ; Trumpp, A. (Last author)
Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1-HER3 signaling.
Nature cancer 6(1), 67-85 (2025) [10.1038/s43018-024-00882-2]2025
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Unterrainer, L. M. ; Hope, T. A. ; Fendler, W. P. ; Grogan, T. ; Ndlovu, H. ; Armstrong, W. ; Barbato, F. ; Benz, M. R. ; Rettig, M. B. ; Kishan, A. U. ; Sathekge, M. ; Herrmann, K. ; Czernin, J. ; Calais, J.
Low- and High-Volume Disease in Metastatic Hormone-Sensitive Prostate Cancer: From CHAARTED to PSMA PET-An International Multicenter Retrospective Study.
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Haeusser, L. A. ; Becker, H. ; Kuhlburger, L. ; Zago, M. ; Walter, B. ; Tsiami, F. ; Erdmann, S. ; Trampert, J. ; Surender, S. ; Stahl, A. ; Templin, M. ; Wegner, E. ; Schmidt, T. ; Schmees, C. ; Casadei, N. ; Sevenich, L. ; Claassen, M. ; Nahnsen, S. ; Beck, S. ; Merk, D. J. ; Tabatabai, G.
Genome-wide CRISPR-Cas 9 screens identify BCL family members as modulators of response to regorafenib in experimental glioma.
Neuro-Oncology nn, nn (2025) [10.1093/neuonc/noae278]2025
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Chicón-Bosch, M. ; Sánchez-Serra, S. ; Rosàs-Lapeña, M. ; Costa-Fraga, N. ; Besalú-Velázquez, J. ; Illa-Bernadí, J. ; Mateo-Lozano, S. ; Cidre-Aranaz, F. ; Grünewald, T. G. P. ; Díaz-Lagares, Á. ; Lopez-Alemany, R. ; Tirado, Ò. M.
Multi-omics profiling reveals key factors involved in Ewing sarcoma metastasis.
Molecular oncology nn, nn (2025) [10.1002/1878-0261.13788]2025
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Hoechstetter, M. A. ; Hollwich, E.-M. ; Illner, D. ; Pham, T.-T. ; von Bergwelt-Baildon, M. ; Dreyling, M. ; Wendtner, C.-M.
SARS-COV-2 Pre-Exposure Prophylaxis With Tixagevimab-Cilgavimab in Haematological, Immunocompromised Patients in the Omicron Era.
European journal of haematology nn, nn (2025) [10.1111/ejh.14377]2025
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Nägler, F. ; Vorbach, S. ; Mohamed, A. A. ; Thaqi, S. ; Adebahr, S. ; Ehret, F. ; Kraft, J. ; Fabian, A. ; Weissmann, T. ; Kaufmann, J. ; Drabke, S. ; Looman, E. L. ; Waltenberger, M. ; Kraus, K. M. ; Grohmann, M. ; Dehl, K. ; Rogers, S. ; Gawish, A. ; Becker, J.-N. ; Klement, R. J. ; Partl, R. ; Trommer, M. ; Grosu, A.-L. ; Rimner, A. ; Gkika, E. ; Riesterer, O. ; Putz, F. ; Ganswindt, U. ; Moustakis, C. ; Nicolay, N. H. ; Brunner, T. B. ; Blanck, O. ; Wittig-Sauerwein, A. ; Balermpas, P. ; Rühle, A.
Pulmonary Stereotactic Body Radiotherapy of Oligometastatic Head-and-Neck Squamous Cell Carcinoma - A multicenter retrospective study.
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Okonechnikov, K. (First author) ; Ghasemi, D. R. ; Schrimpf, D. ; Tonn, S. ; Mynarek, M. ; Koster, J. ; Milde, T. ; Zheng, T. ; Sievers, P. ; Sahm, F. ; Jones, D. T. W. ; von Deimling, A. ; Pfister, S. M. ; Kool, M. ; Pajtler, K. W. ; Korshunov, A. (Last author)
Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.
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Kasan, M. (First author) ; Geyer, F. ; Siebenlist, J. ; Sill, M. ; Öllinger, R. ; Faehling, T. ; de Álava, E. ; Surdez, D. ; Dirksen, U. ; Oehme, I. ; Scotlandi, K. ; Delattre, O. ; Müller-Nurasyid, M. ; Rad, R. ; Strauch, K. ; Grünewald, T. ; Cidre-Aranaz, F. (Last author)
Genomic and phenotypic stability of fusion-driven pediatric sarcoma cell lines.
Nature Communications 16(1), 380 (2025) [10.1038/s41467-024-55340-5]2025
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Schwalm, M. P. ; Menge, A. ; Elson, L. ; Greco, F. A. ; Robers, M. B. ; Müller, S. ; Knapp, S.
Functional Characterization of Pathway Inhibitors for the Ubiquitin-Proteasome System (UPS) as Tool Compounds for CRBN and VHL-Mediated Targeted Protein Degradation.
ACS chemical biology 20(1), 94-104 (2025) [10.1021/acschembio.4c00450]2025
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Sergeev, D. (First author) ; Heisser, T. ; Hoffmeister, M. ; Brenner, H. (Last author)
Potential for enhancing efficacy of screening colonoscopy by lowering starting ages and extending screening intervals: A modelling study for Germany.
International journal of cancer nn, nn (2025) [10.1002/ijc.35322]2025
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Lee, J. J. Y. ; Tao, R. ; You, Z. ; et al
ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip
Nature genetics 57(1), 88-102 (2025) [10.1038/s41588-024-02014-z]2025
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Shin, J. Y. ; Rimner, A. ; Simone, C. B.
In Regard to Ghirardelli et al
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Tschaidse, T. ; Hofmann, F. O. ; Renz, B. ; Hungbauer, M. ; Klinger, C. ; Buhr, H. J. ; Uhl, W. ; Mees, S. T. ; Keck, T. ; Reissfelder, C. ; Ghadimi, M. ; D'Haese, J. G. ; Werner, J. ; Ilmer, M.
Perioperative outcomes in an age-adapted analysis of the German StuDoQ|Pancreas registry for PDAC.
BMC surgery 25(1), 4 (2025) [10.1186/s12893-024-02647-1]2025
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Roohani, S. ; Handtke, J. ; Hummedah, K. ; et al
The sarcoma ring trial: a case-based analysis of inter-center agreement across 21 German-speaking sarcoma centers.
Journal of cancer research and clinical oncology 151(1), 30 (2025) [10.1007/s00432-024-06063-z]2025
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Hricak, H. ; Mayerhoefer, M. E. ; Herrmann, K. ; Lewis, J. S. ; Pomper, M. G. ; Hess, C. P. ; Riklund, K. ; Scott, A. M. ; Weissleder, R.
Advances and challenges in precision imaging
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Braitsch, K. ; Lorenzini, T. ; Hefter, M. ; Koch, K. ; Nickel, K. ; Peeken, J. C. ; Götze, K. S. ; Weber, W. ; Allmann, A. ; D'Alessandria, C. ; Brosch-Lenz, J. ; Bassermann, F. ; Rudelius, M. ; Verbeek, M. ; Eiber, M. ; Herhaus, P.
CXCR4-directed endoradiotherapy with [177Lu]Pentixather added to total body irradiation for myeloablative conditioning in patients with relapsed/refractory acute myeloid leukemia.
Theranostics 15(1), 19 - 29 (2025) [10.7150/thno.101215]2025
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Zein, L. ; Dietrich, M. ; Balta, D. ; Bader, V. ; Scheuer, C. ; Zellner, S. ; Weinelt, N. ; Vandrey, J. ; Mari, M. C. ; Behrends, C. ; Zunke, F. ; Winklhofer, K. F. ; van Wijk, S.
Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival.
Autophagy nn, nn (2025) [10.1080/15548627.2024.2443945]2025
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Tasdogan, A. ; Schadendorf, D. ; Ugurel, S.
Topical ruxolitinib for treatment-induced vitiligo in a patient with metastatic melanoma
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Marmé, F. ; Krieghoff-Henning, E. I. ; Kiehl, L. ; Wies, C. ; Hauke, J. ; Hahnen, E. ; Harter, P. ; Schouten, P. C. ; Brodkorb, T. ; Kayali, M. ; Heitz, F. ; Zamagni, C. ; González-Martin, A. ; Treilleux, I. ; Kommoss, S. ; Prieske, K. ; Gaiser, T. ; Fröhling, S. ; Ray-Coquard, I. ; Pujade-Lauraine, E. ; Brinker, T. (Last author)
Predicting benefit from PARP inhibitors using deep learning on H&E-stained ovarian cancer slides.
European journal of cancer 216, 115199 (2025) [10.1016/j.ejca.2024.115199]2025
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Doglioni, G. ; Fernández-García, J. ; Igelmann, S. ; Altea-Manzano, P. ; Blomme, A. ; La Rovere, R. ; Liu, X.-Z. ; Liu, Y. ; Tricot, T. ; Nobis, M. ; An, N. ; Leclercq, M. ; El Kharraz, S. ; Karras, P. ; Hsieh, Y.-H. ; Solari, F. A. ; Martins Nascentes Melo, L. ; Allies, G. ; Scopelliti, A. ; Rossi, M. ; Vermeire, I. ; Broekaert, D. ; Ferreira Campos, A. M. ; Neven, P. ; Maetens, M. ; Van Baelen, K. ; Alkan, H. F. ; Planque, M. ; Floris, G. ; Sickmann, A. ; Tasdogan, A. ; Marine, J.-C. ; Scheele, C. L. G. J. ; Desmedt, C. ; Bultynck, G. ; Close, P. ; Fendt, S.-M.
Aspartate signalling drives lung metastasis via alternative translation.
Nature 638(8049), 244-250 (2025) [10.1038/s41586-024-08335-7]2025
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Rühle, A. ; Weymann, M. ; Behrens, M. ; Olbrich, J. ; Kut, C. ; Marschner, S. N. ; Haderlein, M. ; Fabian, A. ; Senger, C. ; Bakst, B. P. ; Kraft, J. ; von der Grün, J. ; Looman, E. L. ; Chen, E. ; Domschikowski, J. ; Altay-Langguth, A. ; Kalinauskaite, G. ; Lewitzki, V. ; Bonomi, M. ; Blakaj, D. ; Jhawar, S. R. ; Baliga, S. ; Elguindy, A. N. ; Ferentinos, K. ; Zamboglou, C. ; Müller, J. A. ; Leucht, C. ; Dickstein, D. R. ; Schnellhardt, S. ; Haehl, E. ; Hambsch, P. ; Kuhnt, T. ; Seidel, C. ; Belka, C. ; Mayer, A. ; Schmidberger, H. ; Grosu, A.-L. ; Balermpas, P. ; Stromberger, C. ; Binder, H. ; Quon, H. ; Nicolay, N. H.
Predicting cisplatin tolerability in older adults with head and neck cancer - Insights for improved chemoradiation outcomes.
Radiotherapy and oncology 204, 110697 (2025) [10.1016/j.radonc.2024.110697]2025
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Kießler, M. ; Jäger, C. ; Mota Reyes, C. ; Pergolini, I. ; Schorn, S. ; Göß, R. ; Safak, O. ; Martignoni, M. E. ; Novotny, A. R. ; Uhl, W. ; Werner, J. ; Ghadimi, M. ; Hartwig, W. ; Ruppert, R. ; Keck, T. ; Bruns, C. J. ; Oldhafer, K.-J. ; Schnitzbauer, A. ; Germer, C.-T. ; Sommer, F. ; Mees, S. T. ; Brunner, M. ; Köninger, J. ; Glowka, T. R. ; Kalff, J. C. ; Reißfelder, C. ; Bartsch, D. K. ; Kraus, T. ; Padberg, W. ; Piso, P. ; Lammers, B. J. ; Rudolph, H. ; Moench, C. ; Farkas, S. ; Friess, H. ; Ceyhan, G. O. ; Demir, I. E.
A retrospective, multicentric, nationwide analysis of the impact of splenectomy on survival of pancreatic cancer patients.
Langenbeck's archives of surgery 410(1), 14 (2025) [10.1007/s00423-024-03570-y]2025
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Blöcker, T. ; Lombardo, E. ; Marschner, S. N. ; Belka, C. ; Corradini, S. ; Palacios, M. A. ; Riboldi, M. ; Kurz, C. ; Landry, G.
MRgRT real-time target localization using foundation models for contour point tracking and promptable mask refinement.
Physics in medicine and biology 70(1), 015004 (2025) [10.1088/1361-6560/ad9dad]2025
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Stahler, A. ; Karthaus, M. ; Fruehauf, S. ; Graeven, U. ; Müller, L. ; Fischer von Weikersthal, L. ; Caca, K. ; Goekkurt, E. ; Ballhausen, A. ; Sommerhäuser, G. ; Alig, A. H. S. ; Held, S. ; Jarosch, A. ; Horst, D. ; Reinacher-Schick, A. ; Kasper, S. ; Heinemann, V. ; Stintzing, S. ; Trarbach, T. ; Modest, D. P.
Panitumumab plus 5-fluorouracil and folinic acid or 5-fluorouracil and folinic acid alone as maintenance therapy in RAS wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212): final efficacy analysis of a randomised, open-label, phase 2 trial
EClinicalMedicine 79, 103004 (2025) [10.1016/j.eclinm.2024.103004]2025
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Kurowski, K. ; Föll, M. ; Werner, T. ; Schilling, O. ; Werner, M. ; Fichtner-Feigl, S. ; Bengsch, B. ; Bronsert, P. ; Holzner, P. A. ; Timme, S.
Impact of ALDH1A1 Expression in Intrahepatic Cholangiocellular Carcinoma
Journal of cancer 16(1), 1 - 11 (2025) [10.7150/jca.99944]2025
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Wang, G. ; Liu, D. ; Al-Masri, T. M. ; Otto, C. C. ; Siveke, J. ; Lang, S. A. ; Ulmer, T. F. ; Olde Damink, S. W. ; Luedde, T. ; Dahl, E. ; Neumann, U. P. ; Heij, L. R. ; Bednarsch, J.
Body Composition in Cholangiocarcinoma Affects Immune Cell Populations in the Tumor and Normal Liver Parenchyma
Journal of Clinical and Experimental Hepatology 15(2), 102460 (2025) [10.1016/j.jceh.2024.102460]2025
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Robert, C. ; Long, G. V. ; Larkin, J. ; Wolchok, J. D. ; Hassel, J. C. ; Schadendorf, D. ; Hodi, F. S. ; Lebbé, C. ; Grob, J.-J. ; Hyngstrom, J. R. ; Wagstaff, J. ; Chesney, J. ; Butler, M. O. ; Bechter, O. ; Márquez-Rodas, I. ; Pavlick, A. C. ; Durani, P. ; Pe Benito, M. ; Wang, P. ; Postow, M. A. ; Ascierto, P. A.
Long-term outcomes among patients who respond within the first year to nivolumab plus ipilimumab or nivolumab monotherapy: A pooled analysis in 935 patients
European journal of cancer 214, 115119 (2025) [10.1016/j.ejca.2024.115119]2025
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