DKTK School of Oncology Tech Talk: "State of the Art in Immune Monitoring"

The DKTK School of Oncology will host its third and final Tech Talk featuring Dr. Isabel Poschke, Head of the Immune Monitoring Unit at NCT Heidelberg and scientific team lead within the Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology at the DKFZ.

In her talk, titled “State of the Art in Immune Monitoring”, Dr. Poschke will explore how immune profiling helps researchers understand treatment-induced immune responses and their relationship with clinical outcomes. As immunotherapeutic strategies become increasingly sophisticated, conventional measures of immune activation often fail to capture the breadth, quality and dynamics of T-cell responses.

The seminar will review approaches ranging from multiparametric flow cytometry and functional T-cell assays to T-cell receptor repertoire sequencing, single-cell technologies and antigen-specific T-cell receptor identification. Dr. Poschke will discuss their strengths, limitations and applications in immuno-oncology trials, illustrating how these methods reveal changes in overall immune composition and provide insights into individual antigen-reactive T-cell populations.

The session will conclude with an open discussion and an opportunity for questions.

Registration