Summary

Prof. Dr. med. Louisa von Baumgarten is a senior physician specializing in neuro-oncology at the Department of Neurosurgery at LMU Klinikum in Munich. Her research group focuses on the clinical and experimental study of brain tumor biology and therapy. They investigate the cellular processes involved in the development and spread of primary brain tumors and brain metastases. Additionally, they evaluate the effectiveness of new treatment approaches based on these biological insights. The team uses advanced imaging techniques such as in vivo multiphoton laser scanning microscopy to observe tumor cells, blood vessels, and immune cells in living organisms over time. Their research employs transgenic mouse models and modern molecular biological methods to deepen the understanding of brain tumor biology.

Clinically, Prof. von Baumgarten’s work centers on the management of brain tumors, including both primary tumors and metastases. She studies the effects and side effects of immunotherapies, such as CAR-T cells, immune checkpoint inhibitors, and bispecific antibodies. Furthermore, her group aims to identify biomarkers that can support diagnosis, monitor therapy response, and predict therapy-related toxicity in brain tumor patients. Beyond her research and clinical duties, Prof. von Baumgarten is actively involved in educational and collaborative initiatives in neuro-oncology, including organizing events like the NOA Spring School focused on diagnostic and therapeutic innovations in the field.