Summary

Molecular Tumorpathology

Our research group is interested in “molecular tumorpathology”, focussing on the biology of solid tumours by translational approaches. Our aim is to decipher basic molecular mechanisms of tumour development and progression, in particular with respect to (epi-)genetic instability and signalling pathways. We envisage using this basic molecular knowledge to evaluate novel applications of molecular pathology in a clinically-relevant setting, specifically addressing the issue of therapy prediction. In this context, we continuously work on new development or the “fine-tuning” of “state of the art” techniques for application to human tissue specimens. Close collaboration with other pathology- and clinic-based research groups as well as with research groups in the field of material and natural sciences and biostatistics greatly support our research goals. Our scientific research is embedded within the German Cancer Consortium (DKTK Program “Molecular Diagnostics”, “Molecular Targeted Therapies”) and the Deutsche Forschungsgemeinschaft (SFB850, SFB992).