Providing well characterized biomaterials from cancer patients
Tissue slide staining of paraffin-embedded tumors/tissues © NCT Gewebebank Heidelberg
The CCP Bio is one of four essential Task Forces coordinating the data harmonization of biomaterial collections to be integrated into a joint database.
Human biobanks are collections of biomaterial like tissue, blood or DNA/RNA that is associated with patient and medical data. Well characterized biomaterial from cancer patients is crucial for medical research and the development of new therapies. For cancers with a high incidence like colorectal carcinomas or breast cancer, high numbers of cases are stored at respective sites that can be used for research and yield significant outcomes. However, for rare entities often only small numbers of cases are available making the scientific relevance and research difficult.
Existing biomaterial collections and associated medical data are a result of multiple efforts of physicians and scientists that are often heterogenously documentated and stored at each site. The CCP Bio is the central supportive structure for biobanking in the consortium that connects all participating biobanks, supervises ethical and data protection issues, and coordinates the data harmonization and quality management of biobank operations. By this, biobanking technology and high quality and well characterized biomaterials of cancer patients will be provided for scientists and physicians of the consortium for the facilitation of scientific projects and clinical trials.
In close collaboration with the CCP IT, information on biomaterial collections and clinical data sets of cancer patients were integrated in a joint database to pool available data in the consortium. Scientists can search through this pool of data sets performing a feasibility request via the central search tool. The provision for biomaterial and associated medical data is operated via the decentral search tool and relies on the principle of an inquiry which is formulated centrally and forwarded to all partner sites afterwards. An application for the respective data or material is administered by a central project management located at the CCP Coordination Office, but decisions on the provision of biomaterials and data for joint research projects always remains subject to local rules and regulations.
In the following, all participating biobanks in the consortium are displayed:
Prof Peter Schirmacher (Heidelberg)
Experts of Task Force CCP Bio
- Esmeralda Heiden, Alexandra Stege (Berlin)
- Daniela Aust (Dresden)
- Katharina Jockers, Stefan Palm (Essen)
- Daniel Brucker, Martina Komor (Frankfurt)
- Peter Bronsert, Hannah Füllgraf, Martin Werner, Kristin Werner (Freiburg)
- Esther Herpel (Heidelberg)
- Wilfried Roth (Mainz)
- Corinna Eichelser, Jens Neumann, Julia Slotta-Huspenina (München LMU/TU)
- Falko Fend, Marcus Scharpf (Tübingen)